List of variants in gene SDHB reported as uncertain significance for Gastrointestinal stromal tumor

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 74

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HGVS	dbSNP	gnomAD frequency
NM_003000.3(SDHB):c.403G>A (p.Val135Met)	rs201585157	0.00012
NM_003000.3(SDHB):c.455C>T (p.Ser152Phe)	rs200414835	0.00012
NM_003000.3(SDHB):c.440A>G (p.Tyr147Cys)	rs774568101	0.00010
NM_003000.3(SDHB):c.178A>G (p.Thr60Ala)	rs34599281	0.00007
NM_003000.3(SDHB):c.112C>T (p.Arg38Cys)	rs202119350	0.00006
NM_003000.3(SDHB):c.317A>G (p.Asn106Ser)	rs934514080	0.00006
NM_003000.3(SDHB):c.269G>A (p.Arg90Gln)	rs570278423	0.00004
NM_003000.3(SDHB):c.307A>G (p.Met103Val)	rs140178341	0.00004
NM_003000.3(SDHB):c.530G>A (p.Arg177His)	rs150437793	0.00004
NM_003000.3(SDHB):c.695C>T (p.Ala232Val)	rs746224555	0.00004
NM_003000.3(SDHB):c.200+4A>C	rs774908929	0.00003
NM_003000.3(SDHB):c.344G>A (p.Arg115Gln)	rs200973284	0.00003
NM_003000.3(SDHB):c.130A>G (p.Ile44Val)	rs200418115	0.00002
NM_003000.3(SDHB):c.400T>C (p.Tyr134His)	rs771004483	0.00002
NM_003000.3(SDHB):c.41C>T (p.Pro14Leu)	rs764089231	0.00002
NM_003000.3(SDHB):c.529C>T (p.Arg177Cys)	rs149091125	0.00002
NM_003000.3(SDHB):c.736A>G (p.Ile246Val)	rs146800605	0.00002
NM_003000.3(SDHB):c.739A>G (p.Met247Val)	rs200896502	0.00002
NM_003000.3(SDHB):c.820A>G (p.Lys274Glu)	rs1273897502	0.00002
NM_003000.3(SDHB):c.14T>G (p.Val5Gly)	rs760565241	0.00001
NM_003000.3(SDHB):c.172A>G (p.Met58Val)	rs1201188410	0.00001
NM_003000.3(SDHB):c.214G>A (p.Val72Ile)	rs1060503766	0.00001
NM_003000.3(SDHB):c.31C>T (p.Arg11Cys)	rs200868378	0.00001
NM_003000.3(SDHB):c.323G>A (p.Gly108Asp)	rs767062764	0.00001
NM_003000.3(SDHB):c.362T>C (p.Leu121Pro)	rs775925040	0.00001
NM_003000.3(SDHB):c.457A>G (p.Ile153Val)	rs1450956956	0.00001
NM_003000.3(SDHB):c.458T>C (p.Ile153Thr)	rs1396860069	0.00001
NM_003000.3(SDHB):c.47C>G (p.Thr16Arg)	rs775350144	0.00001
NM_003000.3(SDHB):c.482A>G (p.Asp161Gly)	rs1049317868	0.00001
NM_003000.3(SDHB):c.527A>G (p.Glu176Gly)	rs201082445	0.00001
NM_003000.3(SDHB):c.541G>A (p.Asp181Asn)	rs201385062	0.00001
NM_003000.3(SDHB):c.607G>A (p.Gly203Arg)	rs201517260	0.00001
NM_003000.3(SDHB):c.638T>C (p.Met213Thr)	rs202014362	0.00001
NM_003000.3(SDHB):c.73-6T>A	rs1252798981	0.00001
NM_003000.3(SDHB):c.749C>T (p.Thr250Ile)	rs1057517537	0.00001
NM_003000.3(SDHB):c.7G>A (p.Ala3Thr)	rs765429934	0.00001
NM_003000.3(SDHB):c.101C>G (p.Ala34Gly)	rs867908217
NM_003000.3(SDHB):c.14T>C (p.Val5Ala)	rs760565241
NM_003000.3(SDHB):c.19C>G (p.Leu7Val)	rs745664191
NM_003000.3(SDHB):c.211A>G (p.Met71Val)	rs1557742895
NM_003000.3(SDHB):c.233A>G (p.Lys78Arg)	rs774960237
NM_003000.3(SDHB):c.23C>T (p.Ser8Phe)	rs199848267
NM_003000.3(SDHB):c.241A>T (p.Asn81Tyr)	rs1315623287
NM_003000.3(SDHB):c.256A>T (p.Thr86Ser)	rs1570951385
NM_003000.3(SDHB):c.263C>G (p.Thr88Ser)	rs915794675
NM_003000.3(SDHB):c.269G>T (p.Arg90Leu)	rs570278423
NM_003000.3(SDHB):c.286+5G>A	rs768966871
NM_003000.3(SDHB):c.287-6T>C
NM_003000.3(SDHB):c.29G>A (p.Arg10Lys)	rs1570963545
NM_003000.3(SDHB):c.305C>T (p.Ala102Val)
NM_003000.3(SDHB):c.374C>T (p.Ser125Leu)	rs786203506
NM_003000.3(SDHB):c.379A>C (p.Ile127Leu)	rs201372280
NM_003000.3(SDHB):c.379A>G (p.Ile127Val)	rs201372280
NM_003000.3(SDHB):c.395A>G (p.His132Arg)	rs74315372
NM_003000.3(SDHB):c.397A>G (p.Met133Val)	rs1392546433
NM_003000.3(SDHB):c.398T>C (p.Met133Thr)	rs553392349
NM_003000.3(SDHB):c.447G>T (p.Gln149His)	rs200353146
NM_003000.3(SDHB):c.472AAG[2] (p.Lys160del)	rs1173714647
NM_003000.3(SDHB):c.481G>A (p.Asp161Asn)	rs1553177682
NM_003000.3(SDHB):c.493G>A (p.Glu165Lys)	rs2101521665
NM_003000.3(SDHB):c.540+11C>T	rs1160578491
NM_003000.3(SDHB):c.559A>G (p.Ile187Val)	rs1557739989
NM_003000.3(SDHB):c.5C>T (p.Ala2Val)	rs199948437
NM_003000.3(SDHB):c.614A>G (p.Lys205Arg)	rs774090318
NM_003000.3(SDHB):c.637A>T (p.Met213Leu)	rs770622939
NM_003000.3(SDHB):c.658A>G (p.Ile220Val)	rs1188548211
NM_003000.3(SDHB):c.695C>G (p.Ala232Gly)
NM_003000.3(SDHB):c.708C>G (p.Asp236Glu)
NM_003000.3(SDHB):c.716C>G (p.Ser239Cys)	rs201098090
NM_003000.3(SDHB):c.716C>T (p.Ser239Phe)	rs201098090
NM_003000.3(SDHB):c.721T>G (p.Tyr241Asp)	rs1060503758
NM_003000.3(SDHB):c.782A>C (p.Lys261Thr)	rs1553176980
NM_003000.3(SDHB):c.79C>G (p.Arg27Gly)	rs74315369
NM_003000.3(SDHB):c.822G>T (p.Lys274Asn)

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