List of variants in gene LZTR1 reported as likely pathogenic for Hereditary cancer-predisposing syndrome; Cardiovascular phenotype

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 86

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HGVS	dbSNP	gnomAD frequency
NM_006767.4(LZTR1):c.1397G>A (p.Arg466Gln)	rs587777180	0.00006
NM_006767.4(LZTR1):c.2062C>T (p.Arg688Cys)	rs587777178	0.00006
NM_006767.4(LZTR1):c.2387T>C (p.Ile796Thr)	rs141672122	0.00005
NM_006767.4(LZTR1):c.1943-1G>A	rs1189015572	0.00004
NM_006767.4(LZTR1):c.842C>T (p.Pro281Leu)	rs1390048261	0.00003
NM_006767.4(LZTR1):c.2326-2A>G	rs1475060729	0.00002
NM_006767.4(LZTR1):c.1785+1G>A	rs145594158	0.00001
NM_006767.4(LZTR1):c.2002G>T (p.Asp668Tyr)	rs776005012	0.00001
NM_006767.4(LZTR1):c.2406+1G>A	rs770322736	0.00001
NM_006767.4(LZTR1):c.320G>C (p.Arg107Thr)	rs1301901369	0.00001
NM_006767.4(LZTR1):c.401-2_401-1del	rs769200796	0.00001
NM_006767.4(LZTR1):c.510-2A>G	rs1458682620	0.00001
NM_006767.4(LZTR1):c.651+1G>T	rs1450044732	0.00001
NM_006767.4(LZTR1):c.1150-1G>T
NM_006767.4(LZTR1):c.1247T>G (p.Met416Arg)
NM_006767.4(LZTR1):c.1260+1G>T
NM_006767.4(LZTR1):c.1260G>A (p.Gln420=)
NM_006767.4(LZTR1):c.1353+1G>T
NM_006767.4(LZTR1):c.1397G>T (p.Arg466Leu)	rs587777180
NM_006767.4(LZTR1):c.1449+1G>C
NM_006767.4(LZTR1):c.1449+1G>T
NM_006767.4(LZTR1):c.1449+2T>C
NM_006767.4(LZTR1):c.1449+2T>G
NM_006767.4(LZTR1):c.1449G>A (p.Gln483=)
NM_006767.4(LZTR1):c.1449G>C (p.Gln483His)
NM_006767.4(LZTR1):c.1615+1G>A
NM_006767.4(LZTR1):c.1616-1G>A
NM_006767.4(LZTR1):c.1616-1G>C
NM_006767.4(LZTR1):c.1616-2A>C
NM_006767.4(LZTR1):c.1616-2A>G	rs1328046881
NM_006767.4(LZTR1):c.1616-2_1616-1delinsCC
NM_006767.4(LZTR1):c.1785+2T>A
NM_006767.4(LZTR1):c.1785+2T>C
NM_006767.4(LZTR1):c.1785+2T>G
NM_006767.4(LZTR1):c.1786-1_1786dup
NM_006767.4(LZTR1):c.1942+1G>C
NM_006767.4(LZTR1):c.1942+1G>T
NM_006767.4(LZTR1):c.1942+2T>C
NM_006767.4(LZTR1):c.1943-1G>T
NM_006767.4(LZTR1):c.1943-320G>C
NM_006767.4(LZTR1):c.200+1G>T
NM_006767.4(LZTR1):c.200+1dup
NM_006767.4(LZTR1):c.200+2T>A
NM_006767.4(LZTR1):c.200G>C (p.Arg67Pro)
NM_006767.4(LZTR1):c.2069+2T>G
NM_006767.4(LZTR1):c.2070-1G>A
NM_006767.4(LZTR1):c.2070-2A>G	rs774954465
NM_006767.4(LZTR1):c.2325+1G>C
NM_006767.4(LZTR1):c.2325+2T>C
NM_006767.4(LZTR1):c.2348_2351del (p.Thr783fs)	rs587777179
NM_006767.4(LZTR1):c.2353_2360delinsTG (p.Ala785_Asp787delinsCys)
NM_006767.4(LZTR1):c.2406+1G>C
NM_006767.4(LZTR1):c.2406+2T>C
NM_006767.4(LZTR1):c.263+1del	rs1924258572
NM_006767.4(LZTR1):c.263G>A (p.Gly88Glu)
NM_006767.4(LZTR1):c.263G>T (p.Gly88Val)	rs1051725799
NM_006767.4(LZTR1):c.264-2A>C
NM_006767.4(LZTR1):c.320+1G>A	rs943939913
NM_006767.4(LZTR1):c.320+1G>C	rs943939913
NM_006767.4(LZTR1):c.320+2T>G
NM_006767.4(LZTR1):c.320+5del	rs1924365049
NM_006767.4(LZTR1):c.321-1G>A
NM_006767.4(LZTR1):c.347C>T (p.Ala116Val)
NM_006767.4(LZTR1):c.400+1G>A
NM_006767.4(LZTR1):c.400+1G>C	rs1555927561
NM_006767.4(LZTR1):c.400+5G>A
NM_006767.4(LZTR1):c.401-1G>C	rs747225246
NM_006767.4(LZTR1):c.401-2del
NM_006767.4(LZTR1):c.509+3G>C
NM_006767.4(LZTR1):c.509G>T (p.Arg170Leu)	rs781431741
NM_006767.4(LZTR1):c.565A>T (p.Ile189Phe)
NM_006767.4(LZTR1):c.577T>C (p.Tyr193His)	rs2147962725
NM_006767.4(LZTR1):c.594-3C>G
NM_006767.4(LZTR1):c.650A>T (p.Glu217Val)
NM_006767.4(LZTR1):c.651+1G>A
NM_006767.4(LZTR1):c.651G>A (p.Glu217=)
NM_006767.4(LZTR1):c.652-1G>A
NM_006767.4(LZTR1):c.652-2A>C
NM_006767.4(LZTR1):c.791+1G>A	rs148031742
NM_006767.4(LZTR1):c.791+1G>T
NM_006767.4(LZTR1):c.792-1G>A
NM_006767.4(LZTR1):c.792-2A>G
NM_006767.4(LZTR1):c.993+2T>G
NM_006767.4(LZTR1):c.994-1G>A
NM_006767.4(LZTR1):c.994-1G>T	rs758238174
NM_006767.4(LZTR1):c.994-2A>G

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