List of variants in gene STK11 reported as pathogenic for Hereditary cancer-predisposing syndrome

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 101

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HGVS	dbSNP	gnomAD frequency
NM_000455.5(STK11):c.290+1G>A	rs1131690950	0.00001
NM_000455.5(STK11):c.106del (p.Tyr36fs)	rs1131690924
NM_000455.5(STK11):c.107dup (p.Tyr36Ter)
NM_000455.5(STK11):c.108C>G (p.Tyr36Ter)	rs137853079
NM_000455.5(STK11):c.109C>T (p.Gln37Ter)	rs121913324
NM_000455.5(STK11):c.134_145del (p.Leu45_Tyr49delinsHis)	rs730881958
NM_000455.5(STK11):c.156_157del (p.Asp53fs)	rs1131690917
NM_000455.5(STK11):c.156_157dup (p.Asp53fs)
NM_000455.5(STK11):c.157del (p.Asp53fs)
NM_000455.5(STK11):c.157dup (p.Asp53fs)	rs1131690917
NM_000455.5(STK11):c.169dup (p.Glu57fs)	rs121913319
NM_000455.5(STK11):c.179_180insAA (p.Tyr60Ter)	rs876661012
NM_000455.5(STK11):c.180C>A (p.Tyr60Ter)	rs778376925
NM_000455.5(STK11):c.180C>G (p.Tyr60Ter)	rs778376925
NM_000455.5(STK11):c.180del (p.Ser59_Tyr60insTer)	rs1555735008
NM_000455.5(STK11):c.195_198del (p.Glu65fs)	rs1131690936
NM_000455.5(STK11):c.209dup (p.Thr71fs)	rs1131690929
NM_000455.5(STK11):c.218_230del (p.Cys73fs)	rs730881959
NM_000455.5(STK11):c.242del (p.Lys81fs)	rs1599915235
NM_000455.5(STK11):c.246del (p.Lys83fs)
NM_000455.5(STK11):c.250A>T (p.Lys84Ter)	rs137853076
NM_000455.5(STK11):c.256del (p.Arg86fs)
NM_000455.5(STK11):c.267del (p.Asn90fs)
NM_000455.5(STK11):c.288_289dup (p.Lys97fs)	rs2080673579
NM_000455.5(STK11):c.290+1G>T	rs1131690950
NM_000455.5(STK11):c.291-1G>A	rs112675807
NM_000455.5(STK11):c.291-2A>G	rs876658584
NM_000455.5(STK11):c.357del (p.Asn119fs)	rs1555737444
NM_000455.5(STK11):c.358G>T (p.Glu120Ter)	rs775595174
NM_000455.5(STK11):c.363_367dup (p.Gln123fs)	rs1131690933
NM_000455.5(STK11):c.367C>T (p.Gln123Ter)	rs1131690925
NM_000455.5(STK11):c.373dup (p.Met125fs)	rs1131690952
NM_000455.5(STK11):c.374+1A>G	rs1131690951
NM_000455.5(STK11):c.388G>T (p.Glu130Ter)	rs1599925303
NM_000455.5(STK11):c.396C>A (p.Cys132Ter)	rs730881969
NM_000455.5(STK11):c.402_403del (p.Cys134fs)	rs587782424
NM_000455.5(STK11):c.409C>T (p.Gln137Ter)	rs730881970
NM_000455.5(STK11):c.418del (p.Leu140fs)	rs397518440
NM_000455.5(STK11):c.446del (p.Pro149fs)	rs1131690926
NM_000455.5(STK11):c.462dup (p.Gly155fs)
NM_000455.5(STK11):c.464+1G>T	rs730881971
NM_000455.5(STK11):c.475C>T (p.Gln159Ter)
NM_000455.5(STK11):c.479_489del (p.Leu160fs)
NM_000455.5(STK11):c.487_490del (p.Gly163fs)
NM_000455.5(STK11):c.488G>A (p.Gly163Asp)	rs137853078
NM_000455.5(STK11):c.497_500dup (p.His168fs)	rs1131690922
NM_000455.5(STK11):c.526G>A (p.Asp176Asn)	rs730881979
NM_000455.5(STK11):c.526del (p.Asp176fs)	rs1599926521
NM_000455.5(STK11):c.540del (p.Asn181fs)	rs1131690939
NM_000455.5(STK11):c.540dup (p.Asn181fs)	rs1131690939
NM_000455.5(STK11):c.541_542dup (p.Asn181fs)
NM_000455.5(STK11):c.542A>G (p.Asn181Ser)	rs886037859
NM_000455.5(STK11):c.543C>G (p.Asn181Lys)	rs730881973
NM_000455.5(STK11):c.574del (p.Ile192fs)	rs587781856
NM_000455.5(STK11):c.580G>A (p.Asp194Asn)	rs121913315
NM_000455.5(STK11):c.580G>T (p.Asp194Tyr)	rs121913315
NM_000455.5(STK11):c.597+1G>A
NM_000455.5(STK11):c.598-1G>A	rs1555738319
NM_000455.5(STK11):c.598-2A>G	rs1131690934
NM_000455.5(STK11):c.608dup (p.Phe204fs)	rs1131690946
NM_000455.5(STK11):c.630C>A (p.Cys210Ter)	rs786201213
NM_000455.5(STK11):c.640C>T (p.Gln214Ter)	rs1131690923
NM_000455.5(STK11):c.645del (p.Ser216fs)
NM_000455.5(STK11):c.658C>T (p.Gln220Ter)	rs1131690940
NM_000455.5(STK11):c.663_675del (p.Pro222fs)
NM_000455.5(STK11):c.677del (p.Asn226fs)
NM_000455.5(STK11):c.67del (p.Asp23fs)	rs1555734904
NM_000455.5(STK11):c.719C>A (p.Ser240Ter)	rs730881976
NM_000455.5(STK11):c.734+1G>A	rs587782018
NM_000455.5(STK11):c.734+1G>C	rs587782018
NM_000455.5(STK11):c.734+1G>T	rs587782018
NM_000455.5(STK11):c.735-1G>A	rs1057517830
NM_000455.5(STK11):c.752del (p.Gly251fs)	rs1131690948
NM_000455.5(STK11):c.790_793del (p.Phe264fs)	rs121913320
NM_000455.5(STK11):c.792del (p.Phe264fs)	rs1599927622
NM_000455.5(STK11):c.806del (p.Lys269fs)	rs1599927645
NM_000455.5(STK11):c.816C>A (p.Tyr272Ter)
NM_000455.5(STK11):c.816C>G (p.Tyr272Ter)	rs9282859
NM_000455.5(STK11):c.824del (p.Pro275fs)
NM_000455.5(STK11):c.827del (p.Gly276fs)
NM_000455.5(STK11):c.830_836dup (p.Pro280fs)	rs1599927689
NM_000455.5(STK11):c.842del (p.Pro281fs)	rs121913321
NM_000455.5(STK11):c.842dup (p.Leu282fs)	rs121913321
NM_000455.5(STK11):c.843dup (p.Leu282fs)	rs1131690949
NM_000455.5(STK11):c.862+1G>T	rs1131690921
NM_000455.5(STK11):c.869T>C (p.Leu290Pro)	rs1057524439
NM_000455.5(STK11):c.876C>G (p.Tyr292Ter)	rs148928808
NM_000455.5(STK11):c.876del (p.Glu291_Tyr292insTer)	rs1131690947
NM_000455.5(STK11):c.885del (p.Lys296fs)
NM_000455.5(STK11):c.899del (p.Ile300fs)	rs786203624
NM_000455.5(STK11):c.901del (p.Arg301fs)
NM_000455.5(STK11):c.910C>T (p.Arg304Trp)	rs786201090
NM_000455.5(STK11):c.910del (p.Arg304fs)	rs1064793427
NM_000455.5(STK11):c.911G>C (p.Arg304Pro)	rs376280361
NM_000455.5(STK11):c.913C>T (p.Gln305Ter)	rs1131690945
NM_000455.5(STK11):c.920+1G>A	rs1131690920
NM_000455.5(STK11):c.921-1G>C	rs398123406
NM_000455.5(STK11):c.922_931delinsCC (p.Trp308fs)	rs1599929258
NM_000455.5(STK11):c.923G>A (p.Trp308Ter)	rs864622488
NM_000455.5(STK11):c.93dup (p.Thr32fs)	rs1131690930
NM_000455.5(STK11):c.965del (p.Ile322fs)

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