ClinVar Miner

List of variants reported as pathogenic for Hereditary diffuse gastric adenocarcinoma by Myriad Genetics, Inc.

Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 270
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HGVS dbSNP gnomAD frequency
NM_001903.5(CTNNA1):c.385C>T (p.Arg129Ter) rs758599826 0.00001
NM_004360.5(CDH1):c.1003C>T (p.Arg335Ter) rs587780784 0.00001
NC_000016.10:g.68815516del rs2152134667
NM_001903.5(CTNNA1):c.1006del (p.Glu336fs)
NM_001903.5(CTNNA1):c.1046C>A (p.Ser349Ter)
NM_001903.5(CTNNA1):c.1053C>A (p.Tyr351Ter)
NM_001903.5(CTNNA1):c.1075G>T (p.Glu359Ter)
NM_001903.5(CTNNA1):c.1078_1081del (p.Arg360fs) rs1753991365
NM_001903.5(CTNNA1):c.1134dup (p.Arg379fs)
NM_001903.5(CTNNA1):c.1246_1249del (p.Val416fs) rs1426385729
NM_001903.5(CTNNA1):c.1292_1295del (p.Ile431fs) rs1754363697
NM_001903.5(CTNNA1):c.1325_1328del (p.Asn442fs)
NM_001903.5(CTNNA1):c.1330dup (p.Glu444fs) rs1758714268
NM_001903.5(CTNNA1):c.1350del (p.Arg451fs)
NM_001903.5(CTNNA1):c.1351C>T (p.Arg451Ter) rs201498915
NM_001903.5(CTNNA1):c.1430_1433del (p.Ser477fs)
NM_001903.5(CTNNA1):c.1450dup (p.Met484fs)
NM_001903.5(CTNNA1):c.1464dup (p.Glu489fs)
NM_001903.5(CTNNA1):c.1473G>A (p.Trp491Ter)
NM_001903.5(CTNNA1):c.1474dup (p.Glu492fs)
NM_001903.5(CTNNA1):c.1480C>T (p.Gln494Ter)
NM_001903.5(CTNNA1):c.151_152del (p.Lys51fs) rs2149656252
NM_001903.5(CTNNA1):c.1544C>G (p.Ser515Ter) rs1762138459
NM_001903.5(CTNNA1):c.157_158del (p.Gly53fs)
NM_001903.5(CTNNA1):c.1581dup (p.Ile528fs) rs2150288001
NM_001903.5(CTNNA1):c.1598dup (p.Asp534fs)
NM_001903.5(CTNNA1):c.1613_1617dup (p.Arg540fs) rs1580854940
NM_001903.5(CTNNA1):c.1636C>T (p.Arg546Ter) rs1763609978
NM_001903.5(CTNNA1):c.1636del (p.Arg546fs)
NM_001903.5(CTNNA1):c.1768C>T (p.Gln590Ter) rs926691029
NM_001903.5(CTNNA1):c.1815del (p.Met606fs)
NM_001903.5(CTNNA1):c.1822G>T (p.Glu608Ter)
NM_001903.5(CTNNA1):c.1904_1905del (p.Pro635fs)
NM_001903.5(CTNNA1):c.1906del (p.Glu636fs)
NM_001903.5(CTNNA1):c.1928_1929del (p.Asp642_Phe643insTer)
NM_001903.5(CTNNA1):c.1969C>T (p.Gln657Ter) rs1764805365
NM_001903.5(CTNNA1):c.2023C>T (p.Gln675Ter) rs1580907792
NM_001903.5(CTNNA1):c.214_215del (p.Phe72fs)
NM_001903.5(CTNNA1):c.222_223del (p.Lys75fs) rs1580984414
NM_001903.5(CTNNA1):c.292C>T (p.Arg98Ter) rs773235871
NM_001903.5(CTNNA1):c.361C>T (p.Arg121Ter) rs1043413100
NM_001903.5(CTNNA1):c.382dup (p.Ala128fs)
NM_001903.5(CTNNA1):c.39G>A (p.Trp13Ter)
NM_001903.5(CTNNA1):c.406dup (p.Thr136fs) rs1581105774
NM_001903.5(CTNNA1):c.580del (p.Arg194fs)
NM_001903.5(CTNNA1):c.583C>T (p.Gln195Ter)
NM_001903.5(CTNNA1):c.608_623del (p.His203fs)
NM_001903.5(CTNNA1):c.660_666del (p.Tyr222fs)
NM_001903.5(CTNNA1):c.68dup (p.Ala24fs) rs2149651992
NM_001903.5(CTNNA1):c.739C>T (p.Gln247Ter)
NM_001903.5(CTNNA1):c.86del (p.Leu29fs) rs745411817
NM_001903.5(CTNNA1):c.887dup (p.Ser297fs)
NM_001903.5(CTNNA1):c.892G>T (p.Glu298Ter)
NM_001903.5(CTNNA1):c.919del (p.Glu307fs) rs1760848495
NM_001903.5(CTNNA1):c.994C>T (p.Arg332Ter)
NM_001903.5(CTNNA1):c.99del (p.Thr34fs)
NM_004360.5(CDH1):c.1009_1010del (p.Ser337Phefs) rs786201045
NM_004360.5(CDH1):c.1020_1051del (p.Tyr341fs)
NM_004360.5(CDH1):c.103G>T (p.Glu35Ter) rs1597838625
NM_004360.5(CDH1):c.1040_1041dup (p.Ala348fs)
NM_004360.5(CDH1):c.1051C>T (p.Gln351Ter) rs1555515726
NM_004360.5(CDH1):c.1062dup (p.Leu355fs)
NM_004360.5(CDH1):c.1064del (p.Gly354_Leu355insTer) rs1555515731
NM_004360.5(CDH1):c.1064dup (p.Leu355fs) rs1555515731
NM_004360.5(CDH1):c.1078del (p.Thr360fs)
NM_004360.5(CDH1):c.1091_1092del (p.Thr364fs)
NM_004360.5(CDH1):c.1097_1112del (p.Thr366fs)
NM_004360.5(CDH1):c.1098_1099insAA (p.Asp367fs)
NM_004360.5(CDH1):c.1098_1101del (p.Asp367fs)
NM_004360.5(CDH1):c.1123_1129del (p.Phe375fs)
NM_004360.5(CDH1):c.1131del (p.Thr378fs) rs1131690812
NM_004360.5(CDH1):c.1143_1145delinsA (p.Gly382fs)
NM_004360.5(CDH1):c.1145del (p.Gly382fs) rs1555515863
NM_004360.5(CDH1):c.1155dup (p.Glu386Ter)
NM_004360.5(CDH1):c.1162G>T (p.Glu388Ter)
NM_004360.5(CDH1):c.11G>A (p.Trp4Ter) rs1962423346
NM_004360.5(CDH1):c.1212del (p.Asn405fs) rs1597895871
NM_004360.5(CDH1):c.1212dup (p.Asn405fs) rs1597895871
NM_004360.5(CDH1):c.1222dup (p.Ala408fs)
NM_004360.5(CDH1):c.1226G>A (p.Trp409Ter)
NM_004360.5(CDH1):c.1228G>T (p.Glu410Ter)
NM_004360.5(CDH1):c.1234_1235dup (p.Ile415fs) rs1567507825
NM_004360.5(CDH1):c.124_126delinsT (p.Pro42fs) rs876658865
NM_004360.5(CDH1):c.1273del (p.Val425fs)
NM_004360.5(CDH1):c.1295_1296delinsTTTT (p.Asn432fs)
NM_004360.5(CDH1):c.12G>A (p.Trp4Ter) rs1555509636
NM_004360.5(CDH1):c.1301del (p.Gly434fs)
NM_004360.5(CDH1):c.1312del (p.Thr438fs) rs1555515920
NM_004360.5(CDH1):c.1315_1316delinsCAA (p.Ala439fs)
NM_004360.5(CDH1):c.1338_1345del (p.Lys447fs)
NM_004360.5(CDH1):c.1340_1346del (p.Lys447fs)
NM_004360.5(CDH1):c.1342C>T (p.Gln448Ter)
NM_004360.5(CDH1):c.1343dup (p.Gln449fs)
NM_004360.5(CDH1):c.1350C>G (p.Tyr450Ter)
NM_004360.5(CDH1):c.1354_1357del (p.Leu452fs) rs886039612
NM_004360.5(CDH1):c.1369del (p.Thr457fs) rs1960959718
NM_004360.5(CDH1):c.136del (p.Leu46fs)
NM_004360.5(CDH1):c.137del (p.Leu46fs)
NM_004360.5(CDH1):c.1380del (p.Pro461fs) rs1567508847
NM_004360.5(CDH1):c.1386del (p.Phe462fs)
NM_004360.5(CDH1):c.1397_1398del (p.Leu466fs) rs1597897893
NM_004360.5(CDH1):c.1438_1453del (p.Val480fs)
NM_004360.5(CDH1):c.1450_1463del (p.Pro484fs)
NM_004360.5(CDH1):c.1467del (p.Glu490fs)
NM_004360.5(CDH1):c.1476_1477del (p.Arg492fs) rs876659208
NM_004360.5(CDH1):c.1480G>T (p.Glu494Ter) rs778871891
NM_004360.5(CDH1):c.1488_1494del (p.Glu497fs) rs876658261
NM_004360.5(CDH1):c.1489G>T (p.Glu497Ter)
NM_004360.5(CDH1):c.1492del (p.Asp498fs)
NM_004360.5(CDH1):c.1531C>T (p.Gln511Ter) rs1131690810
NM_004360.5(CDH1):c.1541_1565delinsTGTAGT (p.Asp514_Thr522delinsValTer)
NM_004360.5(CDH1):c.1543dup (p.Thr515fs)
NM_004360.5(CDH1):c.1544_1545del (p.Thr515fs)
NM_004360.5(CDH1):c.1555C>T (p.Gln519Ter)
NM_004360.5(CDH1):c.1569T>A (p.Tyr523Ter) rs876659716
NM_004360.5(CDH1):c.1569T>G (p.Tyr523Ter) rs876659716
NM_004360.5(CDH1):c.1577G>A (p.Trp526Ter) rs1596960298
NM_004360.5(CDH1):c.1578G>A (p.Trp526Ter) rs886039590
NM_004360.5(CDH1):c.1582_1583del (p.Asp528fs)
NM_004360.5(CDH1):c.1587dup (p.Ala530fs) rs1555516532
NM_004360.5(CDH1):c.1590dup (p.Asn531fs) rs1555516535
NM_004360.5(CDH1):c.1595G>A (p.Trp532Ter) rs1596960368
NM_004360.5(CDH1):c.1600dup (p.Glu534fs)
NM_004360.5(CDH1):c.1605del (p.Asn536fs) rs1596960393
NM_004360.5(CDH1):c.1629del (p.Thr544fs)
NM_004360.5(CDH1):c.1660G>T (p.Glu554Ter)
NM_004360.5(CDH1):c.1679dup (p.Tyr561fs) rs1555516567
NM_004360.5(CDH1):c.1682dup (p.Tyr561Ter)
NM_004360.5(CDH1):c.1689_1694delinsACGTA (p.Leu564fs)
NM_004360.5(CDH1):c.1710del (p.Asn570fs) rs1961081411
NM_004360.5(CDH1):c.172G>T (p.Glu58Ter)
NM_004360.5(CDH1):c.1746dup (p.Leu583fs) rs1131690817
NM_004360.5(CDH1):c.1779del (p.Ile594fs) rs876661118
NM_004360.5(CDH1):c.1779dup (p.Ile594fs) rs876661118
NM_004360.5(CDH1):c.1792C>T (p.Arg598Ter) rs121964877
NM_004360.5(CDH1):c.1795del (p.Thr599fs)
NM_004360.5(CDH1):c.1828C>T (p.Gln610Ter)
NM_004360.5(CDH1):c.1840del (p.Ile614fs)
NM_004360.5(CDH1):c.1878_1885del (p.Phe626fs) rs2152138505
NM_004360.5(CDH1):c.187C>T (p.Arg63Ter) rs587783047
NM_004360.5(CDH1):c.1889del (p.Leu630fs)
NM_004360.5(CDH1):c.1893dup (p.His632fs) rs1596963827
NM_004360.5(CDH1):c.1895_1896del (p.His632fs) rs1060501224
NM_004360.5(CDH1):c.1913G>A (p.Trp638Ter) rs1567512585
NM_004360.5(CDH1):c.1914G>A (p.Trp638Ter) rs1961170989
NM_004360.5(CDH1):c.1921C>T (p.Gln641Ter) rs587782750
NM_004360.5(CDH1):c.1928del (p.Asn643fs)
NM_004360.5(CDH1):c.1935_1936+9del
NM_004360.5(CDH1):c.1939C>T (p.Gln647Ter) rs778195664
NM_004360.5(CDH1):c.1942G>T (p.Glu648Ter) rs971882211
NM_004360.5(CDH1):c.1948_1949del (p.Ile650fs) rs1555517074
NM_004360.5(CDH1):c.1955dup (p.Leu652fs)
NM_004360.5(CDH1):c.1979dup (p.Gly661_Asp662insTer) rs730881653
NM_004360.5(CDH1):c.1982del (p.Gly661fs) rs1596965628
NM_004360.5(CDH1):c.1993del (p.Ile665fs) rs1567513227
NM_004360.5(CDH1):c.1999del (p.Leu667fs) rs786202033
NM_004360.5(CDH1):c.2029dup (p.Gln677fs) rs1555517100
NM_004360.5(CDH1):c.202del (p.Tyr68fs) rs786202151
NM_004360.5(CDH1):c.2049_2056del (p.Val683_Ser684insTer)
NM_004360.5(CDH1):c.2064_2065del (p.Cys688_Glu689delinsTer) rs587781276
NM_004360.5(CDH1):c.2095C>T (p.Gln699Ter) rs121964874
NM_004360.5(CDH1):c.2100del (p.Val701fs) rs1555517136
NM_004360.5(CDH1):c.2114del (p.Leu705fs)
NM_004360.5(CDH1):c.2144del (p.Gly715fs) rs1555517153
NM_004360.5(CDH1):c.2200A>T (p.Arg734Ter)
NM_004360.5(CDH1):c.220C>T (p.Arg74Ter) rs876658932
NM_004360.5(CDH1):c.2220del (p.Leu741fs)
NM_004360.5(CDH1):c.2222T>G (p.Leu741Ter)
NM_004360.5(CDH1):c.2275G>T (p.Gly759Ter)
NM_004360.5(CDH1):c.2276del (p.Gly759fs) rs1555517680
NM_004360.5(CDH1):c.2287G>T (p.Glu763Ter) rs587780787
NM_004360.5(CDH1):c.228dup (p.Val77fs)
NM_004360.5(CDH1):c.2293C>T (p.Gln765Ter) rs876658575
NM_004360.5(CDH1):c.2293dup (p.Gln765fs)
NM_004360.5(CDH1):c.2296-1G>A rs1057517542
NM_004360.5(CDH1):c.2297_2307delinsTTGA (p.Asp766fs)
NM_004360.5(CDH1):c.2301del (p.Phe767fs)
NM_004360.5(CDH1):c.2311C>T (p.Gln771Ter) rs1131690813
NM_004360.5(CDH1):c.2351_2352del (p.Arg784fs)
NM_004360.5(CDH1):c.2355_2356insCAACCCTCATGGT (p.Asp786delinsGlnProSerTrpTer)
NM_004360.5(CDH1):c.2386dup (p.Arg796fs) rs1375617541
NM_004360.5(CDH1):c.2398del (p.Arg800fs) rs587783048
NM_004360.5(CDH1):c.2416G>T (p.Glu806Ter)
NM_004360.5(CDH1):c.2422G>T (p.Gly808Ter)
NM_004360.5(CDH1):c.2430del (p.Phe810fs) rs786203752
NM_004360.5(CDH1):c.244_248del (p.Val82fs)
NM_004360.5(CDH1):c.2474dup (p.Pro826fs) rs1555518221
NM_004360.5(CDH1):c.247delinsGTGTGG (p.Ile83fs)
NM_004360.5(CDH1):c.2480dup (p.Tyr827Ter) rs1596976243
NM_004360.5(CDH1):c.259dup (p.Arg87fs)
NM_004360.5(CDH1):c.25_26del (p.Ser9fs)
NM_004360.5(CDH1):c.261del (p.Arg87fs) rs1555514429
NM_004360.5(CDH1):c.267dup (p.Arg90fs)
NM_004360.5(CDH1):c.26C>A (p.Ser9Ter) rs1555509646
NM_004360.5(CDH1):c.283C>T (p.Gln95Ter) rs781409616
NM_004360.5(CDH1):c.294delinsTT (p.Leu99fs)
NM_004360.5(CDH1):c.301_314del (p.Tyr101fs)
NM_004360.5(CDH1):c.303C>G (p.Tyr101Ter)
NM_004360.5(CDH1):c.308G>A (p.Trp103Ter) rs1555514464
NM_004360.5(CDH1):c.309G>A (p.Trp103Ter) rs2152126900
NM_004360.5(CDH1):c.315del (p.Thr106fs) rs1064795703
NM_004360.5(CDH1):c.321C>G (p.Tyr107Ter) rs765929630
NM_004360.5(CDH1):c.326del (p.Lys109fs)
NM_004360.5(CDH1):c.331del (p.Ser111fs)
NM_004360.5(CDH1):c.333del (p.Thr112fs)
NM_004360.5(CDH1):c.360dup (p.His121fs) rs878854690
NM_004360.5(CDH1):c.376_382del (p.Pro126fs)
NM_004360.5(CDH1):c.376_382dup (p.His128fs) rs1567501500
NM_004360.5(CDH1):c.377del (p.Pro126fs) rs1060501215
NM_004360.5(CDH1):c.377dup (p.Pro127fs) rs1060501215
NM_004360.5(CDH1):c.382del (p.His128fs) rs1555514492
NM_004360.5(CDH1):c.384dup (p.Gln129fs)
NM_004360.5(CDH1):c.385C>T (p.Gln129Ter)
NM_004360.5(CDH1):c.414_415dup (p.Leu139fs)
NM_004360.5(CDH1):c.419_420del (p.Leu140fs)
NM_004360.5(CDH1):c.42dup (p.Leu15fs)
NM_004360.5(CDH1):c.438_439del (p.Pro147fs) rs1555515197
NM_004360.5(CDH1):c.454_460del (p.Gln152fs) rs1131690815
NM_004360.5(CDH1):c.454_460dup (p.Arg154fs) rs1131690815
NM_004360.5(CDH1):c.455_465del (p.Gln152fs) rs1555515210
NM_004360.5(CDH1):c.456_457delinsTT (p.Gln152_Lys153delinsHisTer)
NM_004360.5(CDH1):c.464_467dup (p.Trp156Ter)
NM_004360.5(CDH1):c.46C>T (p.Gln16Ter)
NM_004360.5(CDH1):c.47dup (p.Val17fs)
NM_004360.5(CDH1):c.48+1G>A rs1440280370
NM_004360.5(CDH1):c.48+1G>C
NM_004360.5(CDH1):c.480_486delinsAGAATA (p.Ile161fs) rs1555515217
NM_004360.5(CDH1):c.484_485delinsT (p.Cys163fs)
NM_004360.5(CDH1):c.504del (p.Gly169fs) rs864622655
NM_004360.5(CDH1):c.506del (p.Gly169fs)
NM_004360.5(CDH1):c.521dup (p.Asn174fs) rs587781290
NM_004360.5(CDH1):c.553G>T (p.Glu185Ter)
NM_004360.5(CDH1):c.570C>A (p.Tyr190Ter) rs761753486
NM_004360.5(CDH1):c.570C>G (p.Tyr190Ter)
NM_004360.5(CDH1):c.59G>A (p.Trp20Ter) rs121964875
NM_004360.5(CDH1):c.602_603del (p.Pro201fs)
NM_004360.5(CDH1):c.602dup (p.Val202fs)
NM_004360.5(CDH1):c.603del (p.Val202fs) rs1131690809
NM_004360.5(CDH1):c.60G>A (p.Trp20Ter) rs786203576
NM_004360.5(CDH1):c.628G>T (p.Glu210Ter)
NM_004360.5(CDH1):c.632_633del (p.Thr211fs)
NM_004360.5(CDH1):c.634G>T (p.Gly212Ter)
NM_004360.5(CDH1):c.638G>A (p.Trp213Ter)
NM_004360.5(CDH1):c.639G>A (p.Trp213Ter)
NM_004360.5(CDH1):c.640del (p.Trp213_Leu214insTer)
NM_004360.5(CDH1):c.64_80del (p.Cys22fs)
NM_004360.5(CDH1):c.656del (p.Pro219fs) rs1555515284
NM_004360.5(CDH1):c.67C>T (p.Gln23Ter) rs1962456814
NM_004360.5(CDH1):c.696_697del (p.His233fs) rs1060501214
NM_004360.5(CDH1):c.696_750del (p.His233fs)
NM_004360.5(CDH1):c.698dup (p.His233fs)
NM_004360.5(CDH1):c.720del (p.Asn240fs) rs1131690819
NM_004360.5(CDH1):c.737_760delinsGGGC (p.Met246fs)
NM_004360.5(CDH1):c.763C>T (p.Gln255Ter)
NM_004360.5(CDH1):c.76G>T (p.Glu26Ter) rs786201058
NM_004360.5(CDH1):c.807dup (p.Ser270fs)
NM_004360.5(CDH1):c.817G>T (p.Glu273Ter)
NM_004360.5(CDH1):c.81del (p.Cys28fs)
NM_004360.5(CDH1):c.830del (p.Pro277fs)
NM_004360.5(CDH1):c.846_847delinsTT (p.Met282_Glu283delinsIleTer)
NM_004360.5(CDH1):c.84C>A (p.Cys28Ter)
NM_004360.5(CDH1):c.878dup (p.Asn294fs)
NM_004360.5(CDH1):c.885del (p.Tyr296fs)
NM_004360.5(CDH1):c.888C>G (p.Tyr296Ter)
NM_004360.5(CDH1):c.919C>T (p.Gln307Ter)
NM_004360.5(CDH1):c.943_944del (p.Asn315fs) rs2152132067
NM_004360.5(CDH1):c.943_946del (p.Asn315fs)
NM_004360.5(CDH1):c.944del (p.Asn315fs)
NM_004360.5(CDH1):c.968del (p.Thr323fs)
NM_004360.5(CDH1):c.970G>T (p.Gly324Ter)

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