List of variants reported as pathogenic for Li-Fraumeni syndrome by Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine

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Total variants: 11

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HGVS	dbSNP	gnomAD frequency
NM_000546.6(TP53):c.375G>A (p.Thr125=)	rs55863639	0.00001
NM_000546.6(TP53):c.455C>T (p.Pro152Leu)	rs587782705	0.00001
NM_000546.6(TP53):c.473G>A (p.Arg158His)	rs587782144	0.00001
NM_000546.6(TP53):c.524G>A (p.Arg175His)	rs28934578	0.00001
NM_000546.6(TP53):c.733G>A (p.Gly245Ser)	rs28934575	0.00001
NM_000546.6(TP53):c.1024C>T (p.Arg342Ter)	rs730882029
NM_000546.6(TP53):c.586C>T (p.Arg196Ter)	rs397516435
NM_000546.6(TP53):c.637C>T (p.Arg213Ter)	rs397516436
NM_000546.6(TP53):c.638G>A (p.Arg213Gln)	rs587778720
NM_000546.6(TP53):c.742C>T (p.Arg248Trp)	rs121912651
NM_000546.6(TP53):c.949C>T (p.Gln317Ter)	rs764735889

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