List of variants in gene MSH2 reported as likely benign for Lynch syndrome 1; Muir-Torré syndrome; Mismatch repair cancer syndrome 2

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 42

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HGVS	dbSNP	gnomAD frequency
NM_000251.3(MSH2):c.1511-9A>T	rs12998837	0.09123
NM_000251.3(MSH2):c.380A>G (p.Asn127Ser)	rs17217772	0.02317
NM_000251.3(MSH2):c.1666T>C (p.Leu556=)	rs61756466	0.00471
NM_000251.3(MSH2):c.23C>T (p.Thr8Met)	rs17217716	0.00184
NM_000251.3(MSH2):c.819A>G (p.Val273=)	rs146577635	0.00101
NM_000251.3(MSH2):c.55T>C (p.Phe19Leu)	rs141711342	0.00063
NM_000251.3(MSH2):c.1680T>C (p.Asn560=)	rs200056411	0.00043
NM_000251.3(MSH2):c.1661+11C>T	rs377154011	0.00030
NM_000251.3(MSH2):c.1255C>A (p.Gln419Lys)	rs63750006	0.00019
NM_000251.3(MSH2):c.138C>G (p.His46Gln)	rs33946261	0.00019
NM_000251.3(MSH2):c.2537A>G (p.Gln846Arg)	rs140754514	0.00015
NM_000251.3(MSH2):c.766G>A (p.Ala256Thr)	rs377403073	0.00014
NM_000251.3(MSH2):c.505A>G (p.Ile169Val)	rs63750716	0.00013
NM_000251.3(MSH2):c.1690A>G (p.Thr564Ala)	rs55778204	0.00008
NM_000251.3(MSH2):c.843A>T (p.Ser281=)	rs150197753	0.00005
NM_000251.3(MSH2):c.336C>A (p.Ser112=)	rs34312619	0.00004
NM_000251.3(MSH2):c.1617T>C (p.Phe539=)	rs730881759	0.00003
NM_000251.3(MSH2):c.594A>G (p.Glu198=)	rs369685768	0.00003
NM_000251.3(MSH2):c.2459-9T>C	rs776644342	0.00002
NM_000251.3(MSH2):c.2621A>G (p.Tyr874Cys)	rs775390721	0.00002
NM_000251.3(MSH2):c.1221C>G (p.Leu407=)	rs63750813	0.00001
NM_000251.3(MSH2):c.1485A>G (p.Thr495=)	rs767039383	0.00001
NM_000251.3(MSH2):c.2082T>C (p.Phe694=)	rs748210094	0.00001
NM_000251.3(MSH2):c.2224G>A (p.Asp742Asn)	rs879254183	0.00001
NM_000251.3(MSH2):c.2248T>C (p.Leu750=)	rs527725593	0.00001
NM_000251.3(MSH2):c.996G>A (p.Lys332=)	rs863224343	0.00001
NM_000251.3(MSH2):c.1005C>T (p.Thr335=)	rs749117915
NM_000251.3(MSH2):c.1401A>G (p.Glu467=)	rs1558508085
NM_000251.3(MSH2):c.1485A>T (p.Thr495=)
NM_000251.3(MSH2):c.1746C>A (p.Val582=)	rs786201486
NM_000251.3(MSH2):c.2052G>T (p.Val684=)
NM_000251.3(MSH2):c.212-5_212-4del	rs746333570
NM_000251.3(MSH2):c.2210+7G>A	rs374675118
NM_000251.3(MSH2):c.2230T>C (p.Leu744=)	rs1188205467
NM_000251.3(MSH2):c.2670G>A (p.Lys890=)	rs1196909514
NM_000251.3(MSH2):c.2714C>G (p.Thr905Arg)	rs267608022
NM_000251.3(MSH2):c.273TCT[2] (p.Leu94del)	rs267607919
NM_000251.3(MSH2):c.2757T>C (p.Asn919=)	rs1354355913
NM_000251.3(MSH2):c.45C>T (p.Ala15=)	rs876659170
NM_000251.3(MSH2):c.606C>G (p.Pro202=)	rs63750600
NM_000251.3(MSH2):c.690T>C (p.Ala230=)	rs1553351595
NM_000251.3(MSH2):c.930T>C (p.Leu310=)

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