ClinVar Miner

Variants studied for Lynch syndrome II

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
51 30 151 88 24 1 305

Gene and significance breakdown #

Total genes and gene combinations: 1
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
MLH1 51 30 151 88 24 1 305

Submitter and significance breakdown #

Total submitters: 18
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Counsyl 17 14 78 49 4 0 162
Mendelics 1 6 25 34 12 0 78
Illumina Clinical Services Laboratory,Illumina 0 0 51 12 5 0 68
OMIM 27 0 3 0 0 0 30
Center for Human Genetics, Inc,Center for Human Genetics, Inc 3 3 7 2 1 0 16
Diagnostic Laboratory, Department of Genetics,University Medical Center Groningen 2 0 1 2 6 0 11
Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics 1 2 2 0 0 0 5
Institute of Human Genetics, University of Leipzig Medical Center 2 1 1 0 0 0 4
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 2 1 0 0 0 0 3
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology 3 0 0 0 0 0 3
Genome Diagnostics Laboratory,VU University Medical Center Amsterdam 0 0 0 0 3 0 3
Soonchunhyang University Bucheon Hospital,Soonchunhyang University Medical Center 0 0 2 0 0 0 2
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center 0 0 0 0 2 0 2
Genetic Services Laboratory,University of Chicago 1 0 0 0 0 0 1
Centogene AG - the Rare Disease Company 0 1 0 0 0 0 1
Genomic Research Center, Shahid Beheshti University of Medical Sciences 0 1 0 0 0 0 1
Bioscientia Institut fuer Medizinische Diagnostik GmbH,Sonic Healthcare 0 1 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1

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