List of variants studied for Lynch syndrome by CSER _CC_NCGL, University of Washington

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Total variants: 16

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HGVS	dbSNP	gnomAD frequency
NM_000535.7(PMS2):c.2466T>C (p.Leu822=)	rs10000	0.11447
NM_000251.3(MSH2):c.339G>A (p.Lys113=)	rs35898375	0.00313
NM_000179.3(MSH6):c.1526T>C (p.Val509Ala)	rs63751005	0.00067
NM_001040108.2(MLH3):c.3440A>T (p.Asn1147Ile)	rs142124529	0.00035
NM_000251.3(MSH2):c.471C>A (p.Gly157=)	rs61756463	0.00029
NM_000535.7(PMS2):c.944G>A (p.Arg315Gln)	rs116314131	0.00006
NM_000535.7(PMS2):c.1096G>C (p.Asp366His)	rs141769057	0.00003
NM_000179.3(MSH6):c.892C>T (p.Arg298Ter)	rs146816935	0.00001
NM_000249.4(MLH1):c.1637A>G (p.Lys546Arg)	rs587779954	0.00001
NM_000535.7(PMS2):c.1144+1G>A	rs373885654	0.00001
NM_000179.3(MSH6):c.3299C>T (p.Thr1100Met)	rs63750442
NM_000179.3(MSH6):c.383G>T (p.Arg128Leu)	rs63750143
NM_000251.3(MSH2):c.1571G>C (p.Arg524Pro)	rs63751207
NM_000251.3(MSH2):c.1803G>C (p.Gln601His)	rs1553368556
NM_000535.7(PMS2):c.1840A>T (p.Lys614Ter)	rs63750490
NM_002354.3(EPCAM):c.267G>C (p.Gln89His)	rs146480420

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