List of variants in gene MEN1 reported as likely pathogenic for Multiple endocrine neoplasia, type 1

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 104

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HGVS	dbSNP	gnomAD frequency
NM_001370259.2(MEN1):c.1169C>T (p.Pro390Leu)	rs761102084	0.00001
NM_001370259.2(MEN1):c.466G>A (p.Gly156Ser)	rs1085307471	0.00001
NM_001370259.2(MEN1):c.1009G>C (p.Ala337Pro)	rs2071312
NM_001370259.2(MEN1):c.1013dup (p.Gln339fs)	rs386134245
NM_001370259.2(MEN1):c.1024G>C (p.Ala342Pro)	rs776561706
NM_001370259.2(MEN1):c.1049+2T>C	rs1555164946
NM_001370259.2(MEN1):c.1049A>T (p.Asp350Val)
NM_001370259.2(MEN1):c.1063del (p.Arg355fs)	rs386134246
NM_001370259.2(MEN1):c.1102del (p.Ala368fs)	rs2136110242
NM_001370259.2(MEN1):c.1117C>T (p.Pro373Ser)	rs794728627
NM_001370259.2(MEN1):c.113C>A (p.Ser38Tyr)
NM_001370259.2(MEN1):c.113C>T (p.Ser38Phe)	rs794728616
NM_001370259.2(MEN1):c.1174dup (p.Glu392fs)	rs386134247
NM_001370259.2(MEN1):c.1185+1G>A	rs1941661315
NM_001370259.2(MEN1):c.1230del (p.Phe410fs)
NM_001370259.2(MEN1):c.1231G>C (p.Ala411Pro)
NM_001370259.2(MEN1):c.1232C>T (p.Ala411Val)
NM_001370259.2(MEN1):c.1247_1254del (p.Phe416fs)	rs1114167542
NM_001370259.2(MEN1):c.1256G>T (p.Gly419Val)	rs1941615895
NM_001370259.2(MEN1):c.1262G>A (p.Cys421Tyr)	rs386134249
NM_001370259.2(MEN1):c.1267T>C (p.Trp423Arg)	rs1555164270
NM_001370259.2(MEN1):c.1281T>A (p.Ser427Arg)	rs1114167528
NM_001370259.2(MEN1):c.1306T>A (p.Trp436Arg)	rs104894259
NM_001370259.2(MEN1):c.1306T>C (p.Trp436Arg)	rs104894259
NM_001370259.2(MEN1):c.1308G>T (p.Trp436Cys)	rs398124435
NM_001370259.2(MEN1):c.1311dup (p.Thr438fs)	rs1555164184
NM_001370259.2(MEN1):c.1328C>A (p.Ser443Tyr)	rs1060499981
NM_001370259.2(MEN1):c.1340T>C (p.Phe447Ser)	rs1941604532
NM_001370259.2(MEN1):c.1350G>C (p.Gln450His)	rs1592636161
NM_001370259.2(MEN1):c.1354C>G (p.Arg452Gly)
NM_001370259.2(MEN1):c.1355G>C (p.Arg452Pro)	rs775922507
NM_001370259.2(MEN1):c.135G>C (p.Glu45Asp)	rs778670301
NM_001370259.2(MEN1):c.1364T>A (p.Val455Glu)	rs878855189
NM_001370259.2(MEN1):c.137A>C (p.His46Pro)	rs2136192730
NM_001370259.2(MEN1):c.137A>G (p.His46Arg)
NM_001370259.2(MEN1):c.137A>T (p.His46Leu)
NM_001370259.2(MEN1):c.1397_1410del (p.Glu466fs)
NM_001370259.2(MEN1):c.1471G>T (p.Glu491Ter)
NM_001370259.2(MEN1):c.1548dup (p.Lys517fs)	rs761695866
NM_001370259.2(MEN1):c.154C>G (p.Arg52Gly)	rs1555166664
NM_001370259.2(MEN1):c.1564dup (p.Val522fs)	rs1941522995
NM_001370259.2(MEN1):c.1663A>G (p.Ser555Gly)
NM_001370259.2(MEN1):c.1664G>A (p.Ser555Asn)	rs863224527
NM_001370259.2(MEN1):c.1665_1668del (p.Ser555fs)	rs1114167510
NM_001370259.2(MEN1):c.1667AGA[1] (p.Lys557del)	rs794728661
NM_001370259.2(MEN1):c.1673T>C (p.Met558Thr)
NM_001370259.2(MEN1):c.1732C>T (p.Gln578Ter)
NM_001370259.2(MEN1):c.1739del (p.Thr580fs)	rs864622617
NM_001370259.2(MEN1):c.1756C>T (p.Gln586Ter)
NM_001370259.2(MEN1):c.1A>G (p.Met1Val)	rs386134250
NM_001370259.2(MEN1):c.231C>G (p.Tyr77Ter)	rs1555166567
NM_001370259.2(MEN1):c.252dup (p.Ile85fs)	rs386134253
NM_001370259.2(MEN1):c.274del (p.Arg92fs)	rs2136186754
NM_001370259.2(MEN1):c.320dup (p.Arg108fs)
NM_001370259.2(MEN1):c.35C>G (p.Pro12Arg)
NM_001370259.2(MEN1):c.3G>A (p.Met1Ile)	rs786204242
NM_001370259.2(MEN1):c.416A>C (p.His139Pro)
NM_001370259.2(MEN1):c.416A>G (p.His139Arg)	rs1114167515
NM_001370259.2(MEN1):c.417C>A (p.His139Gln)	rs386134254
NM_001370259.2(MEN1):c.417C>G (p.His139Gln)	rs386134254
NM_001370259.2(MEN1):c.428T>G (p.Leu143Arg)
NM_001370259.2(MEN1):c.430T>G (p.Phe144Val)	rs1114167543
NM_001370259.2(MEN1):c.445+1G>A
NM_001370259.2(MEN1):c.445+1G>T
NM_001370259.2(MEN1):c.458A>C (p.Asp153Ala)	rs1565648789
NM_001370259.2(MEN1):c.465_466insAATT (p.Gly156fs)	rs386134255
NM_001370259.2(MEN1):c.466G>T (p.Gly156Cys)	rs1085307471
NM_001370259.2(MEN1):c.491C>T (p.Ala164Val)	rs1565648547
NM_001370259.2(MEN1):c.494G>A (p.Cys165Tyr)	rs1057521111
NM_001370259.2(MEN1):c.503T>C (p.Leu168Pro)	rs386134256
NM_001370259.2(MEN1):c.526G>C (p.Ala176Pro)	rs376872829
NM_001370259.2(MEN1):c.643G>A (p.Val215Met)	rs794728621
NM_001370259.2(MEN1):c.649_654+2del	rs386134258
NM_001370259.2(MEN1):c.64C>A (p.Leu22Met)
NM_001370259.2(MEN1):c.654+3A>G	rs1064793168
NM_001370259.2(MEN1):c.655-15_658del	rs1592649598
NM_001370259.2(MEN1):c.65T>G (p.Leu22Arg)	rs104894256
NM_001370259.2(MEN1):c.721T>C (p.Cys241Arg)	rs1592649108
NM_001370259.2(MEN1):c.725C>T (p.Ala242Val)	rs2136141530
NM_001370259.2(MEN1):c.758C>A (p.Ser253Ter)	rs386134259
NM_001370259.2(MEN1):c.758C>T (p.Ser253Leu)	rs386134259
NM_001370259.2(MEN1):c.762_768dup (p.Leu257fs)	rs1555165488
NM_001370259.2(MEN1):c.763G>A (p.Glu255Lys)	rs104894268
NM_001370259.2(MEN1):c.763G>C (p.Glu255Gln)	rs104894268
NM_001370259.2(MEN1):c.766C>T (p.Leu256Phe)	rs878855198
NM_001370259.2(MEN1):c.767T>C (p.Leu256Pro)
NM_001370259.2(MEN1):c.783+2del
NM_001370259.2(MEN1):c.784-1G>A	rs1555165377
NM_001370259.2(MEN1):c.784-1G>C	rs1555165377
NM_001370259.2(MEN1):c.784-2A>T
NM_001370259.2(MEN1):c.784-9G>A	rs794728625
NM_001370259.2(MEN1):c.818T>C (p.Leu273Pro)	rs1592647281
NM_001370259.2(MEN1):c.818T>G (p.Leu273Arg)
NM_001370259.2(MEN1):c.825-1_825del	rs2136130282
NM_001370259.2(MEN1):c.830C>A (p.Pro277His)	rs1060499973
NM_001370259.2(MEN1):c.912G>T (p.Lys304Asn)	rs1592646211
NM_001370259.2(MEN1):c.955dup (p.Tyr319fs)	rs386134261
NM_001370259.2(MEN1):c.958C>A (p.Pro320Thr)
NM_001370259.2(MEN1):c.959C>T (p.Pro320Leu)	rs1114167469
NM_001370259.2(MEN1):c.970_984del (p.Leu324_His328del)	rs1941723156
NM_001370259.2(MEN1):c.970del (p.Leu324fs)	rs1114167508
NM_001370259.2(MEN1):c.97G>C (p.Asp33His)
NM_001370259.2(MEN1):c.97G>T (p.Asp33Tyr)
NM_001370259.2(MEN1):c.983A>C (p.His328Pro)

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