Variants studied for Neurofibromatosis, familial spinal; Juvenile myelomonocytic leukemia; Neurofibromatosis, type 1; Neurofibromatosis-Noonan syndrome; Café-au-lait macules with pulmonary stenosis

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
69	46	297	98	9	513

Gene and significance breakdown #

Total genes and gene combinations: 2

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
NF1	68	44	294	97	9	506
LOC111811965, MIR4733HG, NF1	1	2	3	1	0	7

Submitter and significance breakdown #

Total submitters: 7

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Fulgent Genetics, Fulgent Genetics	41	29	284	93	0	447
Juno Genomics, Hangzhou Juno Genomics, Inc	26	13	7	0	0	46
Department of Pathology and Laboratory Medicine, Sinai Health System	0	4	4	6	8	22
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago	6	0	4	0	1	11
Diagnostics Services (NGS), CSIR - Centre For Cellular And Molecular Biology	1	0	0	0	0	1
Molecular Genetics Lab, CHRU Brest	1	0	0	0	0	1
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn	1	0	0	0	0	1

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