Variants studied for Non-syndromic X-linked intellectual disability

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
3	3	30	10	11	1	58

Gene and significance breakdown #

Total genes and gene combinations: 17

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
BRWD3	0	0	5	1	3	0	9
POF1B, ZNF711	0	0	0	4	4	0	8
ARHGEF6	0	0	3	4	0	0	7
ZNF81	0	0	5	0	0	0	5
IL1RAPL1	0	0	3	0	1	0	4
RAB39B	0	0	4	0	0	0	4
ZNF711	0	0	2	1	1	0	4
PAK3	0	0	2	0	1	0	3
ACSL4	0	0	2	0	0	0	2
HUWE1	1	0	1	0	0	0	2
PTCHD1	1	1	0	0	0	0	2
ZNF41	0	0	2	0	0	0	2
ZNF674	0	0	1	0	1	0	2
ATP6AP1, FAM50A, GDI1	0	1	0	0	0	0	1
MECP2	1	0	0	0	0	0	1
RLIM	0	1	0	0	0	0	1
TSPAN7	0	0	0	0	0	1	1

Submitter and significance breakdown #

Total submitters: 9

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Illumina Laboratory Services, Illumina	0	0	26	10	11	0	47
Center for Human Genetics, Inc, Center for Human Genetics, Inc	0	0	2	0	0	0	2
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute	1	0	1	0	0	0	2
GenomeConnect - Simons Searchlight	1	1	0	0	0	0	2
Women's Health and Genetics/Laboratory Corporation of America, LabCorp	1	0	0	0	0	0	1
Department of Clinical Science, University of Bergen	0	1	0	0	0	0	1
Center For Human Genetics And Laboratory Diagnostics, Dr. Klein, Dr. Rost And Colleagues	0	0	1	0	0	0	1
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen	0	1	0	0	0	0	1
GenomeConnect - Brain Gene Registry	0	0	0	0	0	1	1

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