List of variants in gene SOS1 reported as benign for Noonan syndrome 4

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 30

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HGVS	dbSNP	gnomAD frequency
NM_005633.4(SOS1):c.2964+43C>A	rs1454223	0.94284
NM_005633.4(SOS1):c.*2567T>A	rs6704656	0.93582
NM_005633.4(SOS1):c.720+25C>G	rs997344	0.92405
NM_005633.4(SOS1):c.*1844A>G	rs10166395	0.81008
NM_005633.4(SOS1):c.*3918T>C	rs1043793	0.79508
NM_005633.4(SOS1):c.*3539T>C	rs1037495	0.79504
NM_005633.4(SOS1):c.*328A>G	rs1059310	0.52005
NM_005633.4(SOS1):c.*805C>A	rs1059313	0.14564
NM_005633.4(SOS1):c.*3724T>C	rs11124658	0.04852
NM_005633.4(SOS1):c.195A>C (p.Arg65=)	rs7609455	0.03624
NM_005633.4(SOS1):c.3081+32A>G	rs6723430	0.02350
NM_005633.4(SOS1):c.1203-20T>C	rs112906251	0.01029
NM_005633.4(SOS1):c.*3458A>C	rs114232209	0.00673
NM_005633.4(SOS1):c.*3569T>C	rs115465194	0.00421
NM_005633.4(SOS1):c.345+15C>T	rs75937422	0.00374
NM_005633.4(SOS1):c.1230G>A (p.Gln410=)	rs141390073	0.00238
NM_005633.4(SOS1):c.3081+13A>G	rs189695571	0.00209
NM_005633.4(SOS1):c.213+16T>C	rs150536159	0.00115
NM_005633.4(SOS1):c.*44T>C	rs182657531	0.00060
NM_005633.4(SOS1):c.1203-13T>A	rs145166996	0.00049
NM_005633.4(SOS1):c.345+12_345+13dup	rs397517167	0.00048
NM_005633.4(SOS1):c.2964+17A>G	rs201906525	0.00018
NM_005633.4(SOS1):c.214-10A>G	rs371447614	0.00014
NM_005633.4(SOS1):c.510+9C>G	rs553448375	0.00004
NM_005633.4(SOS1):c.1333_1336dup	rs35969619
NM_005633.4(SOS1):c.2167+16del	rs79984786
NM_005633.4(SOS1):c.2167+16dup	rs79984786
NM_005633.4(SOS1):c.2511-9del	rs727503436
NM_005633.4(SOS1):c.2674-22C>G	rs61601281
NM_005633.4(SOS1):c.2792-50dup	rs869215095

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