List of variants reported as benign for Noonan syndrome by ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories

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Total variants: 20

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HGVS	dbSNP	gnomAD frequency
NM_005633.4(SOS1):c.2791+53C>T	rs7577088	0.94549
NM_005633.4(SOS1):c.720+25C>G	rs997344	0.92897
NM_002834.5(PTPN11):c.1600-95C>T	rs3741983	0.37076
NM_002834.5(PTPN11):c.14+25G>C	rs7972574	0.05545
NM_002834.5(PTPN11):c.854-21C>T	rs41279090	0.05308
NM_002834.5(PTPN11):c.14+54C>A	rs7973432	0.04259
NM_005633.4(SOS1):c.3081+32A>G	rs6723430	0.02350
NM_002834.5(PTPN11):c.854-30T>C	rs144391508	0.00909
NM_002834.5(PTPN11):c.854-32A>C	rs187389813	0.00867
NM_002834.5(PTPN11):c.757-69T>C	rs150087259	0.00468
NM_005633.4(SOS1):c.3081+26G>A	rs186106971	0.00284
NM_005633.4(SOS1):c.1230G>A (p.Gln410=)	rs141390073	0.00217
NM_002834.5(PTPN11):c.137+35G>A	rs727505387	0.00036
NM_002834.5(PTPN11):c.1599+33A>G	rs727505380	0.00008
NM_002834.5(PTPN11):c.1599+26G>A	rs727505390	0.00001
NM_005633.4(SOS1):c.3347-20T>G	rs727505382	0.00001
NM_002834.3:c.1-140delG
NM_002834.5(PTPN11):c.15-38C>T	rs727505378
NM_005633.3:c.213+15C>G
NM_005633.4(SOS1):c.2964+32T>G	rs727505384

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