List of variants in gene LEP reported as pathogenic for Obesity due to congenital leptin deficiency

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 4

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_000230.3(LEP):c.175G>A (p.Gly59Ser)	rs200575914	0.00001
NM_000230.3(LEP):c.190C>T (p.Pro64Ser)	rs2485445933
NM_000230.3(LEP):c.313C>T (p.Arg105Trp)	rs104894023
NM_000230.3(LEP):c.398del (p.Gly133fs)	rs771139087

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.