ClinVar Miner

List of variants studied for Obesity by Illumina Laboratory Services, Illumina

Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 88
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_000939.4(POMC):c.*63C>T rs1042571 0.15332
NM_138711.6(PPARG):c.1341C>T (p.His447=) rs3856806 0.11181
NM_138711.6(PPARG):c.-8-28078C>G rs1801282 0.08996
NM_005912.3(MC4R):c.-178A>C rs34114122 0.04521
NM_000939.4(POMC):c.282C>T (p.Ser94=) rs28930368 0.02915
NM_000939.4(POMC):c.585C>T (p.Ala195=) rs2071345 0.01639
NM_005912.3(MC4R):c.307G>A (p.Val103Ile) rs2229616 0.01559
NM_005912.3(MC4R):c.594C>T (p.Ile198=) rs61741819 0.01121
NM_005912.3(MC4R):c.751A>C (p.Ile251Leu) rs52820871 0.00746
NM_138711.6(PPARG):c.1281A>G (p.Ser427=) rs41516544 0.00627
NM_000939.4(POMC):c.18C>T (p.Cys6=) rs8192605 0.00562
NM_000939.4(POMC):c.641A>G (p.Glu214Gly) rs80326661 0.00552
NM_001035256.2(POMC):c.-203A>G rs139229417 0.00551
NM_005912.3(MC4R):c.-176A>G rs78877161 0.00427
NM_000939.4(POMC):c.261C>A (p.Phe87Leu) rs199636726 0.00328
NM_005912.3(MC4R):c.606C>A (p.Phe202Leu) rs138281308 0.00282
NM_000939.4(POMC):c.346C>T (p.Leu116=) rs34650613 0.00250
NM_138711.6(PPARG):c.1362C>T (p.Ile454=) rs149367249 0.00244
NM_000939.4(POMC):c.158A>G (p.Asp53Gly) rs28932470 0.00173
NM_138711.6(PPARG):c.150C>T (p.Asp50=) rs112174008 0.00154
NM_000939.4(POMC):c.662A>G (p.Tyr221Cys) rs149540566 0.00096
NM_005912.3(MC4R):c.335C>T (p.Thr112Met) rs13447329 0.00062
NM_005912.3(MC4R):c.468G>A (p.Gln156=) rs144393256 0.00060
NM_138711.6(PPARG):c.348T>C (p.Ala116=) rs147975759 0.00058
NM_005912.3(MC4R):c.-216C>T rs139025325 0.00036
NM_005912.3(MC4R):c.677T>C (p.Ile226Thr) rs193922686 0.00034
NM_005912.3(MC4R):c.523G>A (p.Ala175Thr) rs121913563 0.00029
NM_005912.3(MC4R):c.-386G>A rs756482194 0.00021
NM_000939.4(POMC):c.429C>G (p.His143Gln) rs201519174 0.00019
NM_138711.6(PPARG):c.391-3C>T rs370830238 0.00017
NM_138711.6(PPARG):c.417G>A (p.Leu139=) rs41415646 0.00015
NM_005912.3(MC4R):c.-60C>G rs763156013 0.00014
NM_005912.2(MC4R):c.105C>A (p.Tyr35Ter) rs13447324 0.00012
NM_005912.2(MC4R):c.110A>T (p.Asp37Val) rs13447325 0.00012
NM_005912.3(MC4R):c.972C>T (p.Gly324=) rs150448918 0.00011
NM_000939.4(POMC):c.*120A>G rs886055853 0.00010
NM_000939.4(POMC):c.-20-906C>T rs886055855 0.00010
NM_005912.3(MC4R):c.-220G>A rs772697287 0.00008
NM_000939.4(POMC):c.116C>T (p.Thr39Met) rs200370644 0.00007
NM_005912.3(MC4R):c.-121G>A rs541962206 0.00007
NM_005912.3(MC4R):c.-295A>G rs926966481 0.00006
NM_005912.3(MC4R):c.405A>C (p.Ala135=) rs140773238 0.00006
NM_000939.4(POMC):c.638C>T (p.Ala213Val) rs757423347 0.00004
NM_005912.3(MC4R):c.534G>A (p.Thr178=) rs146056286 0.00004
NM_138711.6(PPARG):c.198C>T (p.Asp66=) rs753817211 0.00004
NM_000939.4(POMC):c.498C>T (p.Asp166=) rs760352559 0.00003
NM_005912.3(MC4R):c.776C>T (p.Ala259Val) rs762825773 0.00003
NM_005912.3(MC4R):c.-64G>A rs1485034384 0.00002
NM_005912.3(MC4R):c.15C>T (p.Thr5=) rs199862517 0.00002
NM_138711.6(PPARG):c.1224A>G (p.Gln408=) rs28763894 0.00002
NM_138711.6(PPARG):c.145G>A (p.Glu49Lys) rs777334819 0.00002
NM_138711.6(PPARG):c.393T>C (p.Gly131=) rs201126401 0.00002
NM_000939.4(POMC):c.491C>T (p.Ala164Val) rs773522618 0.00001
NM_000939.4(POMC):c.4C>T (p.Pro2Ser) rs752925315 0.00001
NM_000939.4(POMC):c.801G>A (p.Glu267=) rs779850714 0.00001
NM_005912.3(MC4R):c.-263A>G rs1915374953 0.00001
NM_005912.3(MC4R):c.-359C>A rs982798124 0.00001
NM_005912.3(MC4R):c.-375G>T rs886054080 0.00001
NM_005912.3(MC4R):c.-66C>T rs886054078 0.00001
NM_005912.3(MC4R):c.21T>C (p.Arg7=) rs760074702 0.00001
NM_005912.3(MC4R):c.373A>G (p.Ile125Val) rs1598932263 0.00001
NM_005912.3(MC4R):c.494G>A (p.Arg165Gln) rs747681609 0.00001
NM_005912.3(MC4R):c.645G>A (p.Met215Ile) rs768687497 0.00001
NM_005912.3(MC4R):c.821A>G (p.Asn274Ser) rs121913561 0.00001
NM_005912.3(MC4R):c.929G>A (p.Arg310Lys) rs1429906794 0.00001
NM_138711.6(PPARG):c.-8-28133C>T rs200479885 0.00001
NM_138711.6(PPARG):c.629G>A (p.Arg210Gln) rs150296212 0.00001
NM_000939.4(POMC):c.-20-904T>C rs886055854
NM_000939.4(POMC):c.283A>G (p.Ser95Gly) rs550376110
NM_000939.4(POMC):c.394C>G (p.Pro132Ala) rs8192606
NM_000939.4(POMC):c.474G>T (p.Lys158Asn) rs373721473
NM_000939.4(POMC):c.642G>A (p.Glu214=) rs1671345551
NM_001035256.2(POMC):c.-263C>A rs556369764
NM_005912.3(MC4R):c.-161C>T rs886054079
NM_005912.3(MC4R):c.-18T>C rs886054077
NM_005912.3(MC4R):c.-360G>A rs530787706
NM_005912.3(MC4R):c.-59G>A rs750662653
NM_005912.3(MC4R):c.201G>A (p.Val67=) rs886054076
NM_005912.3(MC4R):c.655G>T (p.Ala219Ser) rs1915344558
NM_005912.3(MC4R):c.815C>G (p.Pro272Arg) rs1915338291
NM_005912.3(MC4R):c.836G>A (p.Cys279Tyr) rs1915337291
NM_005912.3(MC4R):c.947T>G (p.Ile316Ser) rs121913564
NM_005912.3(MC4R):c.949A>T (p.Ile317Phe) rs778685158
NM_138711.6(PPARG):c.1116C>A (p.Phe372Leu) rs886057902
NM_138711.6(PPARG):c.1419C>T (p.Asp473=) rs886057903
NM_138711.6(PPARG):c.431A>G (p.Asp144Gly) rs1211829538
NM_138711.6(PPARG):c.56A>C (p.Asp19Ala) rs762280243
NM_138711.6(PPARG):c.801C>G (p.Pro267=) rs13306747

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.