ClinVar Miner

List of variants in gene SOS1 reported as uncertain significance for RASopathy

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 466
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HGVS dbSNP gnomAD frequency
NM_005633.4(SOS1):c.233T>G (p.Phe78Cys) rs201352584 0.00019
NM_005633.4(SOS1):c.3286T>A (p.Ser1096Thr) rs376722127 0.00017
NM_005633.4(SOS1):c.3347-1G>A rs141565234 0.00017
NM_005633.4(SOS1):c.2966G>A (p.Arg989Lys) rs202043599 0.00016
NM_005633.4(SOS1):c.3706C>A (p.Pro1236Thr) rs727504636 0.00016
NM_005633.4(SOS1):c.2165G>A (p.Arg722Lys) rs142666652 0.00010
NM_005633.4(SOS1):c.244A>G (p.Ile82Val) rs397517157 0.00009
NM_005633.4(SOS1):c.3322G>A (p.Asp1108Asn) rs199856844 0.00009
NM_005633.4(SOS1):c.1490G>A (p.Arg497Gln) rs371314838 0.00004
NM_005633.4(SOS1):c.1859-3T>C rs199727062 0.00004
NM_005633.4(SOS1):c.2571G>C (p.Glu857Asp) rs757460662 0.00004
NM_005633.4(SOS1):c.2587C>A (p.Gln863Lys) rs141501083 0.00004
NM_005633.4(SOS1):c.3392G>A (p.Arg1131Lys) rs768113420 0.00004
NM_005633.4(SOS1):c.3857C>T (p.Ser1286Phe) rs374341202 0.00004
NM_005633.4(SOS1):c.1523A>G (p.Asn508Ser) rs751404198 0.00003
NM_005633.4(SOS1):c.1558G>A (p.Asp520Asn) rs754115060 0.00003
NM_005633.4(SOS1):c.1988T>C (p.Ile663Thr) rs1048869073 0.00003
NM_005633.4(SOS1):c.2987C>T (p.Pro996Leu) rs200747626 0.00003
NM_005633.4(SOS1):c.3697C>A (p.Leu1233Ile) rs777373438 0.00003
NM_005633.4(SOS1):c.3703C>T (p.Pro1235Ser) rs397517168 0.00003
NM_005633.4(SOS1):c.1010A>G (p.Tyr337Cys) rs724160007 0.00002
NM_005633.4(SOS1):c.1202+5A>G rs1021449471 0.00002
NM_005633.4(SOS1):c.169A>T (p.Asn57Tyr) rs765764610 0.00002
NM_005633.4(SOS1):c.1892A>T (p.Tyr631Phe) rs770664679 0.00002
NM_005633.4(SOS1):c.2138G>A (p.Arg713Gln) rs483352826 0.00002
NM_005633.4(SOS1):c.2369T>C (p.Leu790Ser) rs139859866 0.00002
NM_005633.4(SOS1):c.2513G>A (p.Cys838Tyr) rs747801798 0.00002
NM_005633.4(SOS1):c.2567T>C (p.Ile856Thr) rs778865680 0.00002
NM_005633.4(SOS1):c.3502C>G (p.Pro1168Ala) rs756406841 0.00002
NM_005633.4(SOS1):c.3821C>G (p.Pro1274Arg) rs886041565 0.00002
NM_005633.4(SOS1):c.1000G>A (p.Ala334Thr) rs765820430 0.00001
NM_005633.4(SOS1):c.1007A>G (p.Gln336Arg) rs765028553 0.00001
NM_005633.4(SOS1):c.1170A>G (p.Ile390Met) rs1380491347 0.00001
NM_005633.4(SOS1):c.1202+3G>A rs904487658 0.00001
NM_005633.4(SOS1):c.1266G>A (p.Met422Ile) rs1212129369 0.00001
NM_005633.4(SOS1):c.127G>C (p.Asp43His) rs730881052 0.00001
NM_005633.4(SOS1):c.1303A>G (p.Lys435Glu) rs138920742 0.00001
NM_005633.4(SOS1):c.1385T>A (p.Phe462Tyr) rs730881043 0.00001
NM_005633.4(SOS1):c.143T>C (p.Val48Ala) rs373898570 0.00001
NM_005633.4(SOS1):c.1564A>C (p.Asn522His) rs761094509 0.00001
NM_005633.4(SOS1):c.1568G>A (p.Ser523Asn) rs1156669922 0.00001
NM_005633.4(SOS1):c.1627T>C (p.Ser543Pro) rs981234810 0.00001
NM_005633.4(SOS1):c.1640G>A (p.Arg547Gln) rs149775695 0.00001
NM_005633.4(SOS1):c.1768G>A (p.Glu590Lys) rs730881047 0.00001
NM_005633.4(SOS1):c.1828A>G (p.Ile610Val) rs763425122 0.00001
NM_005633.4(SOS1):c.1931T>C (p.Ile644Thr) rs769891933 0.00001
NM_005633.4(SOS1):c.199G>A (p.Ala67Thr) rs730881053 0.00001
NM_005633.4(SOS1):c.2012G>C (p.Ser671Thr) rs1060503525 0.00001
NM_005633.4(SOS1):c.2089G>T (p.Val697Leu) rs966388444 0.00001
NM_005633.4(SOS1):c.2097C>A (p.His699Gln) rs765074047 0.00001
NM_005633.4(SOS1):c.2105A>G (p.Tyr702Cys) rs757094189 0.00001
NM_005633.4(SOS1):c.2137C>A (p.Arg713=) rs1572822400 0.00001
NM_005633.4(SOS1):c.2279C>T (p.Thr760Ile) rs730881027 0.00001
NM_005633.4(SOS1):c.2344A>G (p.Ile782Val) rs778580742 0.00001
NM_005633.4(SOS1):c.2351T>C (p.Ile784Thr) rs1335137808 0.00001
NM_005633.4(SOS1):c.2489A>G (p.Asn830Ser) rs397517158 0.00001
NM_005633.4(SOS1):c.2684G>A (p.Ser895Asn) rs1164976822 0.00001
NM_005633.4(SOS1):c.2728G>C (p.Asp910His) rs369277679 0.00001
NM_005633.4(SOS1):c.2945G>A (p.Arg982Gln) rs1553351453 0.00001
NM_005633.4(SOS1):c.2998A>T (p.Ser1000Cys) rs730881031 0.00001
NM_005633.4(SOS1):c.2999G>A (p.Ser1000Asn) rs891035934 0.00001
NM_005633.4(SOS1):c.3197G>C (p.Ser1066Thr) rs1428068201 0.00001
NM_005633.4(SOS1):c.3229G>A (p.Ala1077Thr) rs775100470 0.00001
NM_005633.4(SOS1):c.3358G>A (p.Val1120Ile) rs368767111 0.00001
NM_005633.4(SOS1):c.3391+3T>C rs761579423 0.00001
NM_005633.4(SOS1):c.3413T>A (p.Ile1138Lys) rs1433351757 0.00001
NM_005633.4(SOS1):c.3531C>A (p.Asp1177Glu) rs730881049 0.00001
NM_005633.4(SOS1):c.3602G>A (p.Arg1201Gln) rs1422169849 0.00001
NM_005633.4(SOS1):c.3662G>C (p.Arg1221Thr) rs768987761 0.00001
NM_005633.4(SOS1):c.3707C>T (p.Pro1236Leu) rs533661246 0.00001
NM_005633.4(SOS1):c.3721A>G (p.Lys1241Glu) rs367693130 0.00001
NM_005633.4(SOS1):c.3734G>T (p.Gly1245Val) rs397517169 0.00001
NM_005633.4(SOS1):c.3763C>A (p.Pro1255Thr) rs972166211 0.00001
NM_005633.4(SOS1):c.3772C>A (p.Pro1258Thr) rs956446097 0.00001
NM_005633.4(SOS1):c.3884G>A (p.Arg1295Gln) rs1668542997 0.00001
NM_005633.4(SOS1):c.464A>G (p.Tyr155Cys) rs1188280924 0.00001
NM_005633.4(SOS1):c.473C>T (p.Thr158Ile) rs776744951 0.00001
NM_005633.4(SOS1):c.560C>A (p.Ser187Tyr) rs730881038 0.00001
NM_005633.4(SOS1):c.571G>A (p.Glu191Lys) rs886041241 0.00001
NM_005633.4(SOS1):c.643T>C (p.Tyr215His) rs730881039 0.00001
NM_005633.4(SOS1):c.688T>G (p.Phe230Val) rs397517177 0.00001
NM_005633.4(SOS1):c.754A>C (p.Ile252Leu) rs1158811958 0.00001
NM_005633.4(SOS1):c.835G>A (p.Val279Ile) rs188055807 0.00001
NM_005633.4(SOS1):c.847T>C (p.Phe283Leu) rs1222945881 0.00001
NM_005633.4(SOS1):c.864+3A>G rs201119821 0.00001
NM_005633.4(SOS1):c.985G>A (p.Glu329Lys) rs756679265 0.00001
NC_000002.11:g.(?_39249778)_(39255748_?)del
NC_000002.11:g.(?_39278265)_(39347563_?)del
NC_000002.11:g.(?_39278265)_(39347563_?)dup
NC_000002.11:g.(?_39283823)_(39347563_?)dup
NC_000002.11:g.(?_39347457)_(39347563_?)dup
NM_005633.4(SOS1):c.1034C>A (p.Ala345Asp)
NM_005633.4(SOS1):c.1047C>G (p.His349Gln)
NM_005633.4(SOS1):c.1074+12_1074+14delinsGAA
NM_005633.4(SOS1):c.1093G>C (p.Glu365Gln)
NM_005633.4(SOS1):c.1098T>A (p.Asp366Glu) rs730881040
NM_005633.4(SOS1):c.1099C>G (p.Gln367Glu)
NM_005633.4(SOS1):c.1100A>G (p.Gln367Arg)
NM_005633.4(SOS1):c.1100A>T (p.Gln367Leu) rs2124539658
NM_005633.4(SOS1):c.1127C>G (p.Ala376Gly)
NM_005633.4(SOS1):c.1129A>G (p.Ile377Val)
NM_005633.4(SOS1):c.1150C>G (p.Gln384Glu)
NM_005633.4(SOS1):c.1165A>G (p.Lys389Glu) rs2124539595
NM_005633.4(SOS1):c.1166A>C (p.Lys389Thr)
NM_005633.4(SOS1):c.1175C>T (p.Ser392Phe)
NM_005633.4(SOS1):c.1180A>C (p.Ser394Arg)
NM_005633.4(SOS1):c.1199dup (p.Ser401fs) rs2124539539
NM_005633.4(SOS1):c.1206A>C (p.Glu402Asp)
NM_005633.4(SOS1):c.1210G>C (p.Ala404Pro)
NM_005633.4(SOS1):c.1220T>A (p.Phe407Tyr)
NM_005633.4(SOS1):c.1235T>C (p.Met412Thr)
NM_005633.4(SOS1):c.124G>A (p.Asp42Asn) rs1402273679
NM_005633.4(SOS1):c.1252G>C (p.Ala418Pro)
NM_005633.4(SOS1):c.1255A>G (p.Ile419Val)
NM_005633.4(SOS1):c.1262A>T (p.Lys421Met)
NM_005633.4(SOS1):c.1276C>A (p.Gln426Lys) rs1558474706
NM_005633.4(SOS1):c.1285A>G (p.Ile429Val) rs2124537717
NM_005633.4(SOS1):c.1291G>A (p.Gly431Ser) rs1223347034
NM_005633.4(SOS1):c.1306G>C (p.Asp436His)
NM_005633.4(SOS1):c.1333A>G (p.Ile445Val) rs2124537533
NM_005633.4(SOS1):c.1337T>C (p.Met446Thr) rs1669849037
NM_005633.4(SOS1):c.1338G>C (p.Met446Ile)
NM_005633.4(SOS1):c.1352C>G (p.Thr451Arg) rs730880218
NM_005633.4(SOS1):c.1357G>A (p.Val453Ile) rs1669848256
NM_005633.4(SOS1):c.135dup (p.Gln46fs)
NM_005633.4(SOS1):c.1370A>G (p.His457Arg) rs1060503524
NM_005633.4(SOS1):c.1376G>C (p.Arg459Thr)
NM_005633.4(SOS1):c.1405A>T (p.Ile469Phe)
NM_005633.4(SOS1):c.1422T>A (p.Asn474Lys)
NM_005633.4(SOS1):c.1426G>T (p.Gly476Trp)
NM_005633.4(SOS1):c.1432C>T (p.Pro478Ser)
NM_005633.4(SOS1):c.1454A>G (p.Asn485Ser) rs140671910
NM_005633.4(SOS1):c.1466G>A (p.Arg489His) rs994463655
NM_005633.4(SOS1):c.1478A>G (p.Lys493Arg) rs2124537230
NM_005633.4(SOS1):c.1479G>T (p.Lys493Asn) rs2124537221
NM_005633.4(SOS1):c.1487T>A (p.Met496Lys)
NM_005633.4(SOS1):c.148G>A (p.Glu50Lys) rs2148140584
NM_005633.4(SOS1):c.1490G>C (p.Arg497Pro) rs371314838
NM_005633.4(SOS1):c.1493A>G (p.Lys498Arg)
NM_005633.4(SOS1):c.1495G>A (p.Val499Ile) rs1315811250
NM_005633.4(SOS1):c.1495G>T (p.Val499Leu) rs1315811250
NM_005633.4(SOS1):c.1511A>C (p.Lys504Thr) rs2124537140
NM_005633.4(SOS1):c.1534C>T (p.His512Tyr)
NM_005633.4(SOS1):c.1542T>A (p.Phe514Leu)
NM_005633.4(SOS1):c.1548A>G (p.Ile516Met)
NM_005633.4(SOS1):c.1558G>T (p.Asp520Tyr) rs754115060
NM_005633.4(SOS1):c.1569T>G (p.Ser523Arg)
NM_005633.4(SOS1):c.1589C>T (p.Ser530Leu)
NM_005633.4(SOS1):c.1597G>A (p.Glu533Lys)
NM_005633.4(SOS1):c.1611G>C (p.Trp537Cys)
NM_005633.4(SOS1):c.1619C>T (p.Ala540Val) rs2124536870
NM_005633.4(SOS1):c.1645A>G (p.Thr549Ala) rs1558474335
NM_005633.4(SOS1):c.1648_1650del (p.Leu550del) rs1669838767
NM_005633.4(SOS1):c.1658T>C (p.Met553Thr)
NM_005633.4(SOS1):c.1664A>C (p.Asp555Ala)
NM_005633.4(SOS1):c.1666G>A (p.Val556Ile) rs753909912
NM_005633.4(SOS1):c.1670C>T (p.Thr557Ile) rs1245953394
NM_005633.4(SOS1):c.1675C>A (p.Leu559Ile)
NM_005633.4(SOS1):c.1686G>T (p.Glu562Asp) rs199778219
NM_005633.4(SOS1):c.1690G>A (p.Glu564Lys) rs1386900583
NM_005633.4(SOS1):c.1691A>G (p.Glu564Gly)
NM_005633.4(SOS1):c.1709C>T (p.Pro570Leu)
NM_005633.4(SOS1):c.1711A>C (p.Ser571Arg)
NM_005633.4(SOS1):c.1727G>T (p.Arg576Ile) rs1553356023
NM_005633.4(SOS1):c.172A>G (p.Met58Val) rs2148140531
NM_005633.4(SOS1):c.1739C>G (p.Pro580Arg) rs1669835119
NM_005633.4(SOS1):c.1748A>T (p.Glu583Val)
NM_005633.4(SOS1):c.1750G>A (p.Glu584Lys)
NM_005633.4(SOS1):c.1758_1775dup (p.Asn591_Met592insIleIlePheGluGluAsn)
NM_005633.4(SOS1):c.1768G>C (p.Glu590Gln) rs730881047
NM_005633.4(SOS1):c.1790G>T (p.Gly597Val) rs2124536324
NM_005633.4(SOS1):c.1798A>C (p.Ile600Leu) rs373139450
NM_005633.4(SOS1):c.1814C>A (p.Thr605Asn)
NM_005633.4(SOS1):c.182A>T (p.Gln61Leu) rs1671636707
NM_005633.4(SOS1):c.1846C>A (p.His616Asn)
NM_005633.4(SOS1):c.1850T>C (p.Met617Thr) rs775105134
NM_005633.4(SOS1):c.1865A>G (p.Asn622Ser)
NM_005633.4(SOS1):c.1870G>T (p.Val624Phe) rs1669579574
NM_005633.4(SOS1):c.1880T>G (p.Phe627Cys) rs1057518197
NM_005633.4(SOS1):c.191C>T (p.Pro64Leu)
NM_005633.4(SOS1):c.1934T>G (p.Ile645Arg)
NM_005633.4(SOS1):c.1935A>G (p.Ile645Met) rs2124520154
NM_005633.4(SOS1):c.1952C>T (p.Pro651Leu) rs773205186
NM_005633.4(SOS1):c.1960G>C (p.Glu654Gln) rs1669547011
NM_005633.4(SOS1):c.1961A>G (p.Glu654Gly) rs1669546886
NM_005633.4(SOS1):c.1963C>G (p.Pro655Ala) rs2124518554
NM_005633.4(SOS1):c.1979G>A (p.Arg660His)
NM_005633.4(SOS1):c.1981A>T (p.Ile661Leu) rs1181488319
NM_005633.4(SOS1):c.1988T>A (p.Ile663Lys)
NM_005633.4(SOS1):c.198T>G (p.Ser66Arg)
NM_005633.4(SOS1):c.1993A>T (p.Asn665Tyr)
NM_005633.4(SOS1):c.2051C>T (p.Pro684Leu) rs397517155
NM_005633.4(SOS1):c.2059C>G (p.Leu687Val) rs1669541910
NM_005633.4(SOS1):c.205G>C (p.Asp69His)
NM_005633.4(SOS1):c.2063G>A (p.Arg688Gln) rs2124518275
NM_005633.4(SOS1):c.2086T>C (p.Trp696Arg)
NM_005633.4(SOS1):c.2098C>G (p.His700Asp)
NM_005633.4(SOS1):c.2100C>G (p.His700Gln) rs1461692001
NM_005633.4(SOS1):c.2103C>G (p.Phe701Leu) rs2124517580
NM_005633.4(SOS1):c.2123C>T (p.Ala708Val)
NM_005633.4(SOS1):c.213+11_213+12delinsAT
NM_005633.4(SOS1):c.213+4T>A
NM_005633.4(SOS1):c.213+4T>C rs1325380102
NM_005633.4(SOS1):c.2147A>T (p.Glu716Val)
NM_005633.4(SOS1):c.2153T>C (p.Ile718Thr)
NM_005633.4(SOS1):c.2156G>A (p.Gly719Glu) rs200794965
NM_005633.4(SOS1):c.2167+1G>A rs1558469557
NM_005633.4(SOS1):c.2167+6T>A
NM_005633.4(SOS1):c.2171A>T (p.Lys724Ile)
NM_005633.4(SOS1):c.2206A>G (p.Ile736Val)
NM_005633.4(SOS1):c.2223A>C (p.Lys741Asn) rs2124515138
NM_005633.4(SOS1):c.2230A>G (p.Arg744Gly) rs1669494952
NM_005633.4(SOS1):c.2237A>G (p.Asn746Ser) rs975491573
NM_005633.4(SOS1):c.2249ATA[1] (p.Asn751del)
NM_005633.4(SOS1):c.224A>G (p.Gln75Arg)
NM_005633.4(SOS1):c.2258C>T (p.Thr753Ile)
NM_005633.4(SOS1):c.2267G>A (p.Ser756Asn)
NM_005633.4(SOS1):c.2282T>C (p.Val761Ala)
NM_005633.4(SOS1):c.228_229del (p.Ser77fs)
NM_005633.4(SOS1):c.2305G>C (p.Gly769Arg)
NM_005633.4(SOS1):c.2326C>G (p.Leu776Val)
NM_005633.4(SOS1):c.2339_2354del (p.His780fs) rs2124514866
NM_005633.4(SOS1):c.2350A>G (p.Ile784Val)
NM_005633.4(SOS1):c.2356C>T (p.Arg786Ter) rs2124514851
NM_005633.4(SOS1):c.2359C>T (p.Gln787Ter)
NM_005633.4(SOS1):c.2404T>C (p.Ser802Pro)
NM_005633.4(SOS1):c.2436A>C (p.Glu812Asp)
NM_005633.4(SOS1):c.2446A>G (p.Ile816Val) rs2124511484
NM_005633.4(SOS1):c.245T>C (p.Ile82Thr)
NM_005633.4(SOS1):c.2468A>G (p.Lys823Arg) rs1558467976
NM_005633.4(SOS1):c.2489A>T (p.Asn830Ile) rs397517158
NM_005633.4(SOS1):c.2491C>G (p.Leu831Val) rs2124511437
NM_005633.4(SOS1):c.2512T>C (p.Cys838Arg)
NM_005633.4(SOS1):c.2516T>C (p.Ile839Thr)
NM_005633.4(SOS1):c.2522A>C (p.Glu841Ala)
NM_005633.4(SOS1):c.2533T>A (p.Leu845Ile)
NM_005633.4(SOS1):c.2546T>C (p.Val849Ala)
NM_005633.4(SOS1):c.2554G>A (p.Val852Met)
NM_005633.4(SOS1):c.2554G>T (p.Val852Leu)
NM_005633.4(SOS1):c.256G>A (p.Ala86Thr)
NM_005633.4(SOS1):c.2571G>T (p.Glu857Asp)
NM_005633.4(SOS1):c.2590G>A (p.Glu864Lys)
NM_005633.4(SOS1):c.2593T>G (p.Leu865Val) rs2124503349
NM_005633.4(SOS1):c.2595G>C (p.Leu865Phe) rs2124503338
NM_005633.4(SOS1):c.2632A>G (p.Met878Val) rs2124503272
NM_005633.4(SOS1):c.2633T>C (p.Met878Thr)
NM_005633.4(SOS1):c.2639dup (p.Ser881fs)
NM_005633.4(SOS1):c.2655A>T (p.Arg885Ser) rs2124503237
NM_005633.4(SOS1):c.2660A>C (p.Asp887Ala)
NM_005633.4(SOS1):c.2661C>A (p.Asp887Glu) rs2124503229
NM_005633.4(SOS1):c.2670T>A (p.Phe890Leu)
NM_005633.4(SOS1):c.2671G>A (p.Glu891Lys) rs1553353452
NM_005633.4(SOS1):c.267T>A (p.Asp89Glu) rs2124610871
NM_005633.4(SOS1):c.2686C>T (p.Arg896Cys) rs2124501933
NM_005633.4(SOS1):c.2702T>C (p.Leu901Ser) rs2124501920
NM_005633.4(SOS1):c.2708A>C (p.Glu903Ala)
NM_005633.4(SOS1):c.2764A>G (p.Ile922Val) rs780420674
NM_005633.4(SOS1):c.2788T>A (p.Phe930Ile) rs1558465734
NM_005633.4(SOS1):c.2792-6T>G
NM_005633.4(SOS1):c.2803A>C (p.Thr935Pro)
NM_005633.4(SOS1):c.2804C>G (p.Thr935Ser)
NM_005633.4(SOS1):c.2836G>C (p.Glu946Gln) rs1558460847
NM_005633.4(SOS1):c.283G>A (p.Glu95Lys) rs1558493384
NM_005633.4(SOS1):c.283G>C (p.Glu95Gln)
NM_005633.4(SOS1):c.2874T>G (p.Phe958Leu) rs2124479605
NM_005633.4(SOS1):c.2877C>G (p.Ser959Arg)
NM_005633.4(SOS1):c.2980T>G (p.Leu994Val)
NM_005633.4(SOS1):c.3002T>C (p.Met1001Thr) rs2124478911
NM_005633.4(SOS1):c.3010G>A (p.Glu1004Lys)
NM_005633.4(SOS1):c.3011A>G (p.Glu1004Gly) rs2124478876
NM_005633.4(SOS1):c.3012A>C (p.Glu1004Asp)
NM_005633.4(SOS1):c.3017C>T (p.Thr1006Ile)
NM_005633.4(SOS1):c.3032A>C (p.Asn1011Thr) rs8192671
NM_005633.4(SOS1):c.3043G>A (p.Glu1015Lys)
NM_005633.4(SOS1):c.3043G>C (p.Glu1015Gln) rs772348571
NM_005633.4(SOS1):c.3062C>A (p.Pro1021His) rs771279973
NM_005633.4(SOS1):c.3068C>A (p.Pro1023His)
NM_005633.4(SOS1):c.3081+6C>T
NM_005633.4(SOS1):c.3095G>C (p.Ser1032Thr) rs2124475811
NM_005633.4(SOS1):c.3100C>A (p.Pro1034Thr)
NM_005633.4(SOS1):c.311C>A (p.Ser104Tyr)
NM_005633.4(SOS1):c.3134C>T (p.Pro1045Leu)
NM_005633.4(SOS1):c.313C>T (p.Leu105Phe)
NM_005633.4(SOS1):c.3145A>T (p.Thr1049Ser) rs1668858649
NM_005633.4(SOS1):c.3158C>T (p.Pro1053Leu)
NM_005633.4(SOS1):c.3160A>T (p.Thr1054Ser)
NM_005633.4(SOS1):c.3175G>A (p.Glu1059Lys)
NM_005633.4(SOS1):c.3175G>C (p.Glu1059Gln)
NM_005633.4(SOS1):c.3176A>G (p.Glu1059Gly)
NM_005633.4(SOS1):c.3182G>A (p.Arg1061Lys)
NM_005633.4(SOS1):c.3193T>A (p.Tyr1065Asn)
NM_005633.4(SOS1):c.3220G>A (p.Glu1074Lys)
NM_005633.4(SOS1):c.3220G>C (p.Glu1074Gln)
NM_005633.4(SOS1):c.3221A>C (p.Glu1074Ala) rs773504580
NM_005633.4(SOS1):c.3223A>G (p.Ser1075Gly)
NM_005633.4(SOS1):c.3226A>G (p.Thr1076Ala)
NM_005633.4(SOS1):c.3235G>A (p.Ala1079Thr) rs1668854594
NM_005633.4(SOS1):c.3238C>G (p.Pro1080Ala)
NM_005633.4(SOS1):c.3248C>G (p.Pro1083Arg)
NM_005633.4(SOS1):c.3254dup (p.Pro1086fs)
NM_005633.4(SOS1):c.3257C>A (p.Pro1086Gln) rs730881028
NM_005633.4(SOS1):c.3258_3288dup (p.Ser1097fs)
NM_005633.4(SOS1):c.3260dup (p.Leu1087fs) rs1558459711
NM_005633.4(SOS1):c.3265C>T (p.Pro1089Ser)
NM_005633.4(SOS1):c.3268C>T (p.Pro1090Ser)
NM_005633.4(SOS1):c.3272C>G (p.Pro1091Arg)
NM_005633.4(SOS1):c.3287C>G (p.Ser1096Cys)
NM_005633.4(SOS1):c.328A>G (p.Ile110Val) rs1276127499
NM_005633.4(SOS1):c.3298G>C (p.Asp1100His)
NM_005633.4(SOS1):c.329T>A (p.Ile110Asn)
NM_005633.4(SOS1):c.3305G>A (p.Cys1102Tyr) rs2124475187
NM_005633.4(SOS1):c.3311T>A (p.Val1104Glu)
NM_005633.4(SOS1):c.3318T>G (p.Asp1106Glu)
NM_005633.4(SOS1):c.3322G>C (p.Asp1108His) rs199856844
NM_005633.4(SOS1):c.3325C>A (p.His1109Asn)
NM_005633.4(SOS1):c.332A>G (p.His111Arg) rs1572860651
NM_005633.4(SOS1):c.3334C>G (p.Pro1112Ala)
NM_005633.4(SOS1):c.3334C>T (p.Pro1112Ser)
NM_005633.4(SOS1):c.3335C>G (p.Pro1112Arg) rs1668848728
NM_005633.4(SOS1):c.3346+4G>C rs1204153026
NM_005633.4(SOS1):c.3349A>G (p.Asn1117Asp) rs2124462850
NM_005633.4(SOS1):c.3373A>C (p.Thr1125Pro)
NM_005633.4(SOS1):c.338T>C (p.Leu113Ser)
NM_005633.4(SOS1):c.3391+3T>A
NM_005633.4(SOS1):c.3391+3_3391+6del rs756201866
NM_005633.4(SOS1):c.3391+5G>C rs1668654438
NM_005633.4(SOS1):c.3391+6T>G
NM_005633.4(SOS1):c.3392-16A>G
NM_005633.4(SOS1):c.3409T>C (p.Ser1137Pro)
NM_005633.4(SOS1):c.3412A>C (p.Ile1138Leu) rs56248239
NM_005633.4(SOS1):c.3436G>C (p.Glu1146Gln)
NM_005633.4(SOS1):c.3439G>A (p.Val1147Met)
NM_005633.4(SOS1):c.3440T>C (p.Val1147Ala) rs1558455818
NM_005633.4(SOS1):c.345+6G>A
NM_005633.4(SOS1):c.3451C>T (p.Pro1151Ser) rs2124458641
NM_005633.4(SOS1):c.3472C>T (p.Arg1158Ter)
NM_005633.4(SOS1):c.3473G>A (p.Arg1158Gln)
NM_005633.4(SOS1):c.347A>T (p.Glu116Val) rs2124607524
NM_005633.4(SOS1):c.3481T>C (p.Ser1161Pro)
NM_005633.4(SOS1):c.3485C>T (p.Ala1162Val) rs1022820895
NM_005633.4(SOS1):c.3494A>C (p.Glu1165Ala)
NM_005633.4(SOS1):c.3511-14_3511-10del rs760713912
NM_005633.4(SOS1):c.3511A>G (p.Ile1171Val)
NM_005633.4(SOS1):c.3512T>G (p.Ile1171Ser)
NM_005633.4(SOS1):c.3520A>G (p.Lys1174Glu)
NM_005633.4(SOS1):c.3526T>A (p.Leu1176Met)
NM_005633.4(SOS1):c.3526T>G (p.Leu1176Val) rs771115389
NM_005633.4(SOS1):c.3534T>A (p.Ser1178Arg) rs1572796568
NM_005633.4(SOS1):c.3559C>T (p.Pro1187Ser)
NM_005633.4(SOS1):c.3563C>T (p.Thr1188Ile)
NM_005633.4(SOS1):c.3568A>G (p.Lys1190Glu) rs1553349579
NM_005633.4(SOS1):c.356G>A (p.Gly119Asp)
NM_005633.4(SOS1):c.3575A>G (p.Tyr1192Cys)
NM_005633.4(SOS1):c.3575A>T (p.Tyr1192Phe)
NM_005633.4(SOS1):c.3580C>T (p.Pro1194Ser)
NM_005633.4(SOS1):c.3584G>A (p.Arg1195Gln)
NM_005633.4(SOS1):c.3598_3599delinsAC (p.Asp1200Thr) rs1572796492
NM_005633.4(SOS1):c.3600C>A (p.Asp1200Glu) rs141594736
NM_005633.4(SOS1):c.3601C>T (p.Arg1201Trp) rs752395541
NM_005633.4(SOS1):c.3609_3614del (p.Ile1204_Ser1205del)
NM_005633.4(SOS1):c.3644C>T (p.Pro1215Leu) rs730881050
NM_005633.4(SOS1):c.3646C>A (p.Pro1216Thr) rs762129481
NM_005633.4(SOS1):c.3665C>T (p.Thr1222Ile)
NM_005633.4(SOS1):c.3667C>T (p.Pro1223Ser) rs1353982573
NM_005633.4(SOS1):c.3671A>T (p.Asp1224Val)
NM_005633.4(SOS1):c.3673G>A (p.Val1225Ile)
NM_005633.4(SOS1):c.3688C>T (p.Pro1230Ser)
NM_005633.4(SOS1):c.3697C>G (p.Leu1233Val)
NM_005633.4(SOS1):c.3709C>T (p.Pro1237Ser) rs371408734
NM_005633.4(SOS1):c.3718A>G (p.Lys1240Glu)
NM_005633.4(SOS1):c.371A>G (p.His124Arg) rs2124607473
NM_005633.4(SOS1):c.3724dup (p.Ser1242fs) rs1558454973
NM_005633.4(SOS1):c.3731A>G (p.His1244Arg)
NM_005633.4(SOS1):c.3748C>T (p.Pro1250Ser) rs1668548624
NM_005633.4(SOS1):c.3753C>G (p.Asn1251Lys) rs2124454963
NM_005633.4(SOS1):c.3764C>G (p.Pro1255Arg) rs1376446157
NM_005633.4(SOS1):c.3770C>T (p.Thr1257Ile) rs962478091
NM_005633.4(SOS1):c.3775C>G (p.Pro1259Ala)
NM_005633.4(SOS1):c.3778C>G (p.Pro1260Ala) rs779336305
NM_005633.4(SOS1):c.3781C>G (p.Pro1261Ala)
NM_005633.4(SOS1):c.3781C>T (p.Pro1261Ser)
NM_005633.4(SOS1):c.3793T>G (p.Ser1265Ala) rs886056023
NM_005633.4(SOS1):c.3799C>T (p.His1267Tyr)
NM_005633.4(SOS1):c.3802G>C (p.Gly1268Arg)
NM_005633.4(SOS1):c.3808A>G (p.Arg1270Gly)
NM_005633.4(SOS1):c.3832T>A (p.Leu1278Met)
NM_005633.4(SOS1):c.3838C>G (p.Gln1280Glu) rs548519280
NM_005633.4(SOS1):c.3839AAG[3] (p.Glu1281dup) rs1175436231
NM_005633.4(SOS1):c.3841G>A (p.Glu1281Lys)
NM_005633.4(SOS1):c.3866G>A (p.Gly1289Glu)
NM_005633.4(SOS1):c.3869C>T (p.Pro1290Leu)
NM_005633.4(SOS1):c.388A>G (p.Ile130Val) rs2124607438
NM_005633.4(SOS1):c.3901C>G (p.His1301Asp)
NM_005633.4(SOS1):c.3901C>T (p.His1301Tyr)
NM_005633.4(SOS1):c.3914T>G (p.Leu1305Arg)
NM_005633.4(SOS1):c.392T>G (p.Val131Gly)
NM_005633.4(SOS1):c.3935G>C (p.Arg1312Thr)
NM_005633.4(SOS1):c.3944C>G (p.Thr1315Arg) rs779904535
NM_005633.4(SOS1):c.3947A>C (p.His1316Pro)
NM_005633.4(SOS1):c.3950C>T (p.Pro1317Leu) rs2124454104
NM_005633.4(SOS1):c.3955A>G (p.Met1319Val)
NM_005633.4(SOS1):c.3958C>G (p.His1320Asp)
NM_005633.4(SOS1):c.3959A>C (p.His1320Pro)
NM_005633.4(SOS1):c.3960C>G (p.His1320Gln) rs1553349464
NM_005633.4(SOS1):c.3962G>C (p.Arg1321Thr) rs1054147959
NM_005633.4(SOS1):c.3964G>A (p.Asp1322Asn) rs1167931335
NM_005633.4(SOS1):c.3971C>G (p.Pro1324Arg) rs727503434
NM_005633.4(SOS1):c.3980T>C (p.Leu1327Ser)
NM_005633.4(SOS1):c.3987T>A (p.Asn1329Lys) rs936986823
NM_005633.4(SOS1):c.3998C>T (p.Ser1333Phe) rs2124453911
NM_005633.4(SOS1):c.433G>A (p.Val145Ile)
NM_005633.4(SOS1):c.440A>T (p.Asn147Ile)
NM_005633.4(SOS1):c.457del (p.Arg153fs)
NM_005633.4(SOS1):c.458G>A (p.Arg153Gln)
NM_005633.4(SOS1):c.482A>G (p.Asp161Gly)
NM_005633.4(SOS1):c.493G>A (p.Ala165Thr)
NM_005633.4(SOS1):c.494C>G (p.Ala165Gly) rs1558492346
NM_005633.4(SOS1):c.500G>A (p.Cys167Tyr) rs768975865
NM_005633.4(SOS1):c.503C>T (p.Ala168Val)
NM_005633.4(SOS1):c.505G>C (p.Asp169His)
NM_005633.4(SOS1):c.511-4A>G rs2124603917
NM_005633.4(SOS1):c.512T>G (p.Val171Gly) rs397517174
NM_005633.4(SOS1):c.524T>C (p.Met175Thr) rs2124603907
NM_005633.4(SOS1):c.538G>A (p.Val180Ile)
NM_005633.4(SOS1):c.542A>G (p.Glu181Gly)
NM_005633.4(SOS1):c.544G>A (p.Asp182Asn) rs1553362279
NM_005633.4(SOS1):c.548T>C (p.Ile183Thr) rs772569423
NM_005633.4(SOS1):c.548_552delinsATATATTA (p.Ile183_Asn184delinsAsnIleLeu)
NM_005633.4(SOS1):c.554T>C (p.Ile185Thr)
NM_005633.4(SOS1):c.558_562del (p.Leu186fs) rs1553362269
NM_005633.4(SOS1):c.576G>C (p.Glu192Asp)
NM_005633.4(SOS1):c.646A>T (p.Ile216Leu)
NM_005633.4(SOS1):c.647T>C (p.Ile216Thr)
NM_005633.4(SOS1):c.668T>C (p.Ile223Thr) rs397517176
NM_005633.4(SOS1):c.670A>G (p.Lys224Glu) rs889231089
NM_005633.4(SOS1):c.681A>C (p.Arg227Ser)
NM_005633.4(SOS1):c.688T>C (p.Phe230Leu) rs397517177
NM_005633.4(SOS1):c.691G>A (p.Val231Ile) rs1671141416
NM_005633.4(SOS1):c.701C>T (p.Ser234Leu) rs2124603499
NM_005633.4(SOS1):c.715G>C (p.Ala239Pro)
NM_005633.4(SOS1):c.720T>C (p.Asn240=) rs779699814
NM_005633.4(SOS1):c.734T>C (p.Ile245Thr) rs2124597097
NM_005633.4(SOS1):c.735A>G (p.Ile245Met) rs2124597094
NM_005633.4(SOS1):c.742C>T (p.Arg248Cys) rs1671008126
NM_005633.4(SOS1):c.746T>C (p.Ile249Thr) rs1324979194
NM_005633.4(SOS1):c.774G>C (p.Lys258Asn) rs1671006816
NM_005633.4(SOS1):c.782G>A (p.Gly261Asp)
NM_005633.4(SOS1):c.788T>C (p.Ile263Thr) rs1310500908
NM_005633.4(SOS1):c.796A>G (p.Thr266Ala)
NM_005633.4(SOS1):c.800T>C (p.Val267Ala)
NM_005633.4(SOS1):c.800T>G (p.Val267Gly) rs748234666
NM_005633.4(SOS1):c.818G>A (p.Gly273Asp)
NM_005633.4(SOS1):c.845G>T (p.Cys282Phe)
NM_005633.4(SOS1):c.847T>A (p.Phe283Ile) rs1222945881
NM_005633.4(SOS1):c.864+5G>C rs1671003663
NM_005633.4(SOS1):c.868C>A (p.Leu290Met)
NM_005633.4(SOS1):c.88-3T>C
NM_005633.4(SOS1):c.888A>C (p.Glu296Asp)
NM_005633.4(SOS1):c.906T>G (p.Ile302Met) rs2124562866
NM_005633.4(SOS1):c.911G>C (p.Arg304Pro)
NM_005633.4(SOS1):c.919T>A (p.Phe307Ile) rs1670310935
NM_005633.4(SOS1):c.922C>T (p.His308Tyr)
NM_005633.4(SOS1):c.967T>C (p.Tyr323His) rs1670309576
NM_005633.4(SOS1):c.976-3dup rs745490729
NM_005633.4(SOS1):c.982G>A (p.Gly328Ser)
NM_005633.4(SOS1):c.982G>C (p.Gly328Arg)

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