List of variants in gene MPL reported as likely benign for Thrombocythemia 1

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 31

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HGVS	dbSNP	gnomAD frequency
NM_005373.3(MPL):c.*662C>T	rs1763698	0.02711
NM_005373.3(MPL):c.117G>T (p.Lys39Asn)	rs17292650	0.01420
NM_005373.3(MPL):c.*1054G>A	rs139528456	0.01153
NM_005373.3(MPL):c.543T>C (p.Gly181=)	rs17572791	0.00819
NM_005373.3(MPL):c.*709C>T	rs185654501	0.00766
NM_005373.3(MPL):c.1565+5C>T	rs41269541	0.00488
NM_005373.3(MPL):c.210G>A (p.Pro70=)	rs6086	0.00482
NM_005373.3(MPL):c.1653+3G>A	rs149625825	0.00367
NM_005373.3(MPL):c.*1506G>A	rs115780311	0.00362
NM_005373.3(MPL):c.*364C>T	rs138892634	0.00233
NM_005373.3(MPL):c.1654-10T>A	rs200460456	0.00196
NM_005373.3(MPL):c.*1603A>C	rs142139493	0.00182
NM_005373.3(MPL):c.*1180G>A	rs117166528	0.00181
NM_005373.3(MPL):c.*1116G>A	rs144177827	0.00175
NM_005373.3(MPL):c.*573G>A	rs192016153	0.00093
NM_005373.3(MPL):c.*748C>T	rs190071085	0.00087
NM_005373.3(MPL):c.1120A>G (p.Thr374Ala)	rs190983971	0.00082
NM_005373.3(MPL):c.962G>A (p.Arg321Gln)	rs149265851	0.00072
NM_005373.3(MPL):c.1003G>A (p.Glu335Lys)	rs139770726	0.00059
NM_005373.3(MPL):c.1570C>T (p.Leu524=)	rs146372205	0.00055
NM_005373.3(MPL):c.1102G>T (p.Val368Leu)	rs149810307	0.00039
NM_005373.3(MPL):c.*94C>A	rs77858532	0.00027
NM_005373.3(MPL):c.1794C>T (p.Cys598=)	rs143457144	0.00025
NM_005373.3(MPL):c.1666G>T (p.Val556Phe)	rs150004498	0.00023
NM_005373.3(MPL):c.*1486T>C	rs149940158	0.00020
NM_005373.3(MPL):c.690+11C>T	rs144769485	0.00012
NM_005373.3(MPL):c.*1674A>T	rs536844021	0.00010
NM_005373.3(MPL):c.*400C>T	rs558390922	0.00004
NM_005373.3(MPL):c.1609C>T (p.Arg537Trp)	rs148784027	0.00004
NM_005373.3(MPL):c.854-3T>C	rs201514537	0.00001
NM_005373.3(MPL):c.*1126A>G	rs543250497

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