ClinVar Miner

List of variants in gene WFS1 reported as likely benign for Wolfram syndrome 1

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 58
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_006005.3(WFS1):c.997G>A (p.Val333Ile) rs1801212 0.80149
NM_006005.3(WFS1):c.1832G>A (p.Arg611His) rs734312 0.43085
NM_006005.3(WFS1):c.316-164A>G rs111852841 0.02863
NM_006005.3(WFS1):c.2469C>T (p.Ile823=) rs1801215 0.01494
NM_006005.3(WFS1):c.1495C>T (p.Leu499Phe) rs114152068 0.00810
NM_006005.3(WFS1):c.1675G>A (p.Ala559Thr) rs55814513 0.00396
NM_006005.3(WFS1):c.2596G>A (p.Asp866Asn) rs3821945 0.00185
NM_006005.3(WFS1):c.1277G>A (p.Cys426Tyr) rs35218685 0.00160
NM_006005.3(WFS1):c.1321G>A (p.Val441Met) rs150894674 0.00094
NM_006005.3(WFS1):c.1152C>T (p.Phe384=) rs149846741 0.00076
NM_006005.3(WFS1):c.2085C>T (p.Gly695=) rs150568382 0.00043
NM_006005.3(WFS1):c.772G>A (p.Val258Ile) rs757414862 0.00025
NM_006005.3(WFS1):c.2364C>T (p.Asp788=) rs144030395 0.00023
NM_006005.3(WFS1):c.1792G>A (p.Ala598Thr) rs140125843 0.00022
NM_006005.3(WFS1):c.1893C>T (p.Ser631=) rs773312242 0.00014
NM_006005.3(WFS1):c.2298C>T (p.His766=) rs755328574 0.00010
NM_006005.3(WFS1):c.1657G>A (p.Gly553Ser) rs150840308 0.00009
NM_006005.3(WFS1):c.2347T>C (p.Phe783Leu) rs71526461 0.00009
NM_006005.3(WFS1):c.747G>A (p.Glu249=) rs752638064 0.00009
NM_006005.3(WFS1):c.792C>G (p.Phe264Leu) rs373669861 0.00007
NM_006005.3(WFS1):c.1191C>T (p.Phe397=) rs201394228 0.00006
NM_006005.3(WFS1):c.2310C>T (p.Phe770=) rs34384569 0.00006
NM_006005.3(WFS1):c.-27C>T rs527868928 0.00005
NM_006005.3(WFS1):c.56C>T (p.Pro19Leu) rs376335216 0.00005
NM_006005.3(WFS1):c.1219C>T (p.His407Tyr) rs151244358 0.00004
NM_006005.3(WFS1):c.143C>T (p.Ala48Val) rs397517195 0.00003
NM_006005.3(WFS1):c.1467C>G (p.Ile489Met) rs768029820 0.00003
NM_006005.3(WFS1):c.1769C>T (p.Thr590Met) rs760280308 0.00003
NM_006005.3(WFS1):c.1896G>T (p.Met632Ile) rs1057524890 0.00002
NM_006005.3(WFS1):c.2246C>T (p.Thr749Met) rs199769524 0.00002
NM_006005.3(WFS1):c.*258A>G rs886059533 0.00001
NM_006005.3(WFS1):c.-4C>T rs746340627 0.00001
NM_006005.3(WFS1):c.1204C>T (p.Leu402=) rs766786172 0.00001
NM_006005.3(WFS1):c.1560G>A (p.Gln520=) rs776513501 0.00001
NM_006005.3(WFS1):c.1623T>G (p.Cys541Trp) rs745712429 0.00001
NM_006005.3(WFS1):c.1986C>T (p.Ser662=) rs1055393876 0.00001
NM_006005.3(WFS1):c.2191A>G (p.Met731Val) rs144010362 0.00001
NM_006005.3(WFS1):c.2286G>A (p.Lys762=) rs200663929 0.00001
NM_006005.3(WFS1):c.2388C>T (p.Asp796=) rs71532868 0.00001
NM_006005.3(WFS1):c.2623G>A (p.Val875Met) rs547459104 0.00001
NM_006005.3(WFS1):c.543G>C (p.Leu181=) rs376651857 0.00001
NM_006005.3(WFS1):c.-43G>C rs1578579501
NM_006005.3(WFS1):c.1294C>G (p.Leu432Val) rs35031397
NM_006005.3(WFS1):c.1382C>T (p.Thr461Ile) rs71530925
NM_006005.3(WFS1):c.1468A>G (p.Thr490Ala) rs1553878548
NM_006005.3(WFS1):c.154C>A (p.Pro52Thr) rs111773340
NM_006005.3(WFS1):c.2350A>C (p.Ser784Arg) rs1560421590
NM_006005.3(WFS1):c.2484C>A (p.Ile828=) rs779957380
NM_006005.3(WFS1):c.2516T>C (p.Val839Ala) rs761114952
NM_006005.3(WFS1):c.417C>T (p.Arg139=) rs377209139
NM_006005.3(WFS1):c.445T>C (p.Leu149=) rs1730394064
NM_006005.3(WFS1):c.461-166_461-165insCA rs56102017
NM_006005.3(WFS1):c.461-169_461-168insAGGAGCATG rs55640037
NM_006005.3(WFS1):c.632-5T>C rs1578597647
NM_006005.3(WFS1):c.771C>T (p.Gly257=) rs747170989
NM_006005.3(WFS1):c.831G>A (p.Lys277=) rs532368033
NM_006005.3(WFS1):c.884C>G (p.Ala295Gly) rs1310473702
NM_006005.3(WFS1):c.996C>T (p.Ile332=) rs138674328

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.