List of variants in gene LYST reported as uncertain significance for not provided

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 104

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HGVS	dbSNP	gnomAD frequency
NM_000081.4(LYST):c.8913T>G (p.Asn2971Lys)	rs34702903	0.00276
NM_000081.4(LYST):c.3683A>G (p.Asn1228Ser)	rs145553827	0.00171
NM_000081.4(LYST):c.8027G>T (p.Ser2676Ile)	rs113209379	0.00086
NM_000081.4(LYST):c.10235G>A (p.Arg3412His)	rs148409403	0.00073
NM_000081.4(LYST):c.11086G>A (p.Val3696Ile)	rs147221131	0.00052
NM_000081.4(LYST):c.8806G>A (p.Val2936Ile)	rs2753327	0.00052
NM_000081.4(LYST):c.3083C>G (p.Ser1028Cys)	rs150636017	0.00049
NM_000081.4(LYST):c.9017A>G (p.Lys3006Arg)	rs140934482	0.00047
NM_000081.4(LYST):c.10526G>A (p.Arg3509Gln)	rs138936105	0.00046
NM_000081.4(LYST):c.143A>G (p.His48Arg)	rs200132460	0.00046
NM_000081.4(LYST):c.3208A>G (p.Ile1070Val)	rs150321124	0.00043
NM_000081.4(LYST):c.6682G>C (p.Asp2228His)	rs150270086	0.00042
NM_000081.4(LYST):c.8960C>G (p.Pro2987Arg)	rs147899661	0.00032
NM_000081.4(LYST):c.2963G>A (p.Arg988Gln)	rs150953050	0.00029
NM_000081.4(LYST):c.4578T>A (p.Asn1526Lys)	rs117609949	0.00025
NM_000081.4(LYST):c.8214G>C (p.Glu2738Asp)	rs140944484	0.00022
NM_000081.4(LYST):c.9045-13T>C	rs181450025	0.00021
NM_000081.4(LYST):c.9552G>T (p.Leu3184Phe)	rs556200563	0.00019
NM_000081.4(LYST):c.595G>A (p.Asp199Asn)	rs552391792	0.00018
NM_000081.4(LYST):c.6388G>A (p.Asp2130Asn)	rs148371004	0.00014
NM_000081.4(LYST):c.7806A>G (p.Gln2602=)	rs372754364	0.00014
NM_000081.4(LYST):c.9473A>G (p.Asn3158Ser)	rs143618409	0.00014
NM_000081.4(LYST):c.2438G>A (p.Arg813Gln)	rs558162561	0.00013
NM_000081.4(LYST):c.3311G>A (p.Arg1104Gln)	rs148299757	0.00011
NM_000081.4(LYST):c.4513A>G (p.Ile1505Val)	rs756527927	0.00011
NM_000081.4(LYST):c.9628-15C>T	rs751859873	0.00011
NM_000081.4(LYST):c.4336C>T (p.Arg1446Trp)	rs200276917	0.00010
NM_000081.4(LYST):c.6332C>A (p.Thr2111Asn)	rs138179493	0.00009
NM_000081.4(LYST):c.7627+6A>T	rs749282192	0.00008
NM_000081.4(LYST):c.9520G>A (p.Val3174Ile)	rs199672291	0.00008
NM_000081.4(LYST):c.3931A>G (p.Met1311Val)	rs376718077	0.00007
NM_000081.4(LYST):c.476G>A (p.Arg159Lys)	rs111806240	0.00007
NM_000081.4(LYST):c.5612T>C (p.Ile1871Thr)	rs559869925	0.00006
NM_000081.4(LYST):c.6149G>A (p.Arg2050Gln)	rs376311093	0.00006
NM_000081.4(LYST):c.7862T>C (p.Met2621Thr)	rs368500877	0.00006
NM_000081.4(LYST):c.110C>T (p.Thr37Met)	rs375106444	0.00004
NM_000081.4(LYST):c.11354G>A (p.Arg3785His)	rs370173269	0.00004
NM_000081.4(LYST):c.1290G>A (p.Met430Ile)	rs779163460	0.00004
NM_000081.4(LYST):c.1541G>A (p.Arg514Gln)	rs564745712	0.00004
NM_000081.4(LYST):c.4705A>C (p.Asn1569His)	rs767687843	0.00004
NM_000081.4(LYST):c.6185G>A (p.Gly2062Glu)	rs756651685	0.00004
NM_000081.4(LYST):c.6737T>G (p.Leu2246Arg)	rs200231136	0.00004
NM_000081.4(LYST):c.10870G>A (p.Val3624Ile)	rs776033238	0.00003
NM_000081.4(LYST):c.7997T>A (p.Ile2666Asn)	rs369246831	0.00003
NM_000081.4(LYST):c.10286T>G (p.Ile3429Ser)	rs760815034	0.00002
NM_000081.4(LYST):c.2870T>C (p.Met957Thr)	rs201554916	0.00002
NM_000081.4(LYST):c.3461C>G (p.Thr1154Arg)	rs756226516	0.00002
NM_000081.4(LYST):c.5833G>A (p.Ala1945Thr)	rs750338502	0.00002
NM_000081.4(LYST):c.7631T>C (p.Met2544Thr)	rs1371610729	0.00002
NM_000081.4(LYST):c.10976G>T (p.Ser3659Ile)	rs1659445104	0.00001
NM_000081.4(LYST):c.11116T>A (p.Cys3706Ser)	rs1481260242	0.00001
NM_000081.4(LYST):c.4288C>G (p.Arg1430Gly)	rs1468055437	0.00001
NM_000081.4(LYST):c.440G>A (p.Arg147His)	rs759868763	0.00001
NM_000081.4(LYST):c.4998C>A (p.Asp1666Glu)	rs377563551	0.00001
NM_000081.4(LYST):c.5578A>G (p.Met1860Val)	rs368738466	0.00001
NM_000081.4(LYST):c.5620T>A (p.Phe1874Ile)	rs757494655	0.00001
NM_000081.4(LYST):c.7340C>T (p.Ala2447Val)	rs766272501	0.00001
NM_000081.4(LYST):c.7780+2C>T	rs760108842	0.00001
NM_000081.4(LYST):c.8143G>A (p.Val2715Ile)	rs202010795	0.00001
NM_000081.4(LYST):c.10492G>C (p.Ala3498Pro)	rs1222770569
NM_000081.4(LYST):c.10598G>C (p.Trp3533Ser)
NM_000081.4(LYST):c.10669G>T (p.Val3557Leu)
NM_000081.4(LYST):c.11101T>G (p.Cys3701Gly)	rs1658277094
NM_000081.4(LYST):c.11362C>T (p.Gln3788Ter)	rs1558092244
NM_000081.4(LYST):c.1535A>G (p.His512Arg)	rs759547330
NM_000081.4(LYST):c.1919G>T (p.Cys640Phe)
NM_000081.4(LYST):c.2009CTT[1] (p.Ser671del)
NM_000081.4(LYST):c.2319_2320delinsAT (p.Leu774Phe)	rs2102878203
NM_000081.4(LYST):c.2656C>G (p.Arg886Gly)	rs1037862310
NM_000081.4(LYST):c.2725G>A (p.Val909Ile)
NM_000081.4(LYST):c.285T>G (p.Asp95Glu)	rs747965676
NM_000081.4(LYST):c.2909T>C (p.Ile970Thr)	rs141758032
NM_000081.4(LYST):c.2919G>T (p.Leu973Phe)
NM_000081.4(LYST):c.2954G>A (p.Gly985Asp)
NM_000081.4(LYST):c.3137A>G (p.Asp1046Gly)
NM_000081.4(LYST):c.3650AAG[2] (p.Glu1219del)	rs770679237
NM_000081.4(LYST):c.3710A>T (p.Asp1237Val)	rs1215274878
NM_000081.4(LYST):c.4321G>C (p.Glu1441Gln)
NM_000081.4(LYST):c.4325G>A (p.Ser1442Asn)	rs1271144759
NM_000081.4(LYST):c.4380G>T (p.Leu1460Phe)	rs768247031
NM_000081.4(LYST):c.479A>G (p.Lys160Arg)	rs2102890869
NM_000081.4(LYST):c.5291G>A (p.Gly1764Asp)	rs35413645
NM_000081.4(LYST):c.5325C>A (p.Phe1775Leu)
NM_000081.4(LYST):c.5373_5374delinsAG (p.Asn1792Asp)
NM_000081.4(LYST):c.5488A>T (p.Thr1830Ser)
NM_000081.4(LYST):c.5719A>G (p.Ile1907Val)
NM_000081.4(LYST):c.5776A>G (p.Lys1926Glu)
NM_000081.4(LYST):c.6390C>G (p.Asp2130Glu)	rs1237420442
NM_000081.4(LYST):c.6781C>T (p.Arg2261Cys)
NM_000081.4(LYST):c.6955C>T (p.Pro2319Ser)
NM_000081.4(LYST):c.7070C>G (p.Ala2357Gly)	rs199576020
NM_000081.4(LYST):c.7098A>C (p.Gln2366His)	rs1013368289
NM_000081.4(LYST):c.7184G>T (p.Cys2395Phe)	rs760878646
NM_000081.4(LYST):c.728C>T (p.Ala243Val)
NM_000081.4(LYST):c.7485G>T (p.Leu2495Phe)
NM_000081.4(LYST):c.7489G>C (p.Ala2497Pro)	rs745703349
NM_000081.4(LYST):c.8033C>G (p.Thr2678Ser)
NM_000081.4(LYST):c.8050G>A (p.Glu2684Lys)
NM_000081.4(LYST):c.8161A>G (p.Lys2721Glu)	rs762099794
NM_000081.4(LYST):c.8306A>G (p.His2769Arg)
NM_000081.4(LYST):c.8590A>G (p.Thr2864Ala)
NM_000081.4(LYST):c.8818C>T (p.Pro2940Ser)	rs375839384
NM_000081.4(LYST):c.9064A>G (p.Ser3022Gly)	rs2103201639
NM_000081.4(LYST):c.9233G>A (p.Arg3078His)

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