List of variants in gene PRX reported as uncertain significance for not provided

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 147

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HGVS	dbSNP	gnomAD frequency
NM_181882.3(PRX):c.445G>A (p.Ala149Thr)	rs142436391	0.00193
NM_181882.3(PRX):c.3373G>A (p.Gly1125Ser)	rs148939995	0.00191
NM_181882.3(PRX):c.2254G>A (p.Glu752Lys)	rs147587689	0.00185
NM_181882.3(PRX):c.3947C>T (p.Ala1316Val)	rs142762689	0.00138
NM_181882.3(PRX):c.1574T>C (p.Val525Ala)	rs149715830	0.00136
NM_181882.3(PRX):c.3838G>C (p.Glu1280Gln)	rs146205352	0.00135
NM_181882.3(PRX):c.823C>A (p.Leu275Ile)	rs200033507	0.00108
NM_181882.3(PRX):c.3186G>T (p.Lys1062Asn)	rs139188673	0.00105
NM_181882.3(PRX):c.3110A>G (p.Glu1037Gly)	rs148600818	0.00099
NM_181882.3(PRX):c.3496C>T (p.Pro1166Ser)	rs147826200	0.00093
NM_181882.3(PRX):c.2548C>G (p.Pro850Ala)	rs141686828	0.00078
NM_181882.3(PRX):c.3145G>A (p.Gly1049Ser)	rs186086914	0.00067
NM_181882.3(PRX):c.499C>T (p.Arg167Cys)	rs10425452	0.00062
NM_181882.3(PRX):c.3769G>A (p.Gly1257Arg)	rs200332462	0.00058
NM_181882.3(PRX):c.361C>T (p.Arg121Trp)	rs750435566	0.00029
NM_181882.3(PRX):c.3580C>G (p.Leu1194Val)	rs149732789	0.00022
NM_181882.3(PRX):c.257G>A (p.Cys86Tyr)	rs565094384	0.00019
NM_181882.3(PRX):c.3209G>A (p.Arg1070Gln)	rs146222815	0.00019
NM_181882.3(PRX):c.4366G>C (p.Ala1456Pro)	rs149093940	0.00019
NM_181882.3(PRX):c.500G>C (p.Arg167Pro)	rs757322355	0.00019
NM_181882.3(PRX):c.2278G>A (p.Val760Met)	rs548905150	0.00017
NM_181882.3(PRX):c.3656C>T (p.Pro1219Leu)	rs201393544	0.00017
NM_181882.3(PRX):c.2449C>T (p.Arg817Cys)	rs147441856	0.00014
NM_181882.3(PRX):c.1387G>T (p.Val463Phe)	rs764004836	0.00013
NM_181882.3(PRX):c.4151C>T (p.Ala1384Val)	rs201618230	0.00013
NM_181882.3(PRX):c.1129G>T (p.Val377Leu)	rs754081921	0.00011
NM_181882.3(PRX):c.16C>G (p.Arg6Gly)	rs759056060	0.00010
NM_181882.3(PRX):c.2909G>A (p.Arg970Gln)	rs764162630	0.00010
NM_181882.3(PRX):c.2463C>T (p.Gly821=)	rs368481955	0.00009
NM_181882.3(PRX):c.3346G>T (p.Val1116Leu)	rs148075077	0.00009
NM_181882.3(PRX):c.4129C>T (p.Arg1377Cys)	rs768524850	0.00009
NM_181882.3(PRX):c.862G>A (p.Val288Met)	rs568618329	0.00009
NM_181882.3(PRX):c.1546C>T (p.Arg516Trp)	rs144305922	0.00008
NM_181882.3(PRX):c.3271G>A (p.Ala1091Thr)	rs368459753	0.00008
NM_181882.3(PRX):c.4017C>A (p.Ser1339Arg)	rs758057597	0.00008
NM_181882.3(PRX):c.574C>T (p.Arg192Trp)	rs780147663	0.00008
NM_181882.3(PRX):c.1040G>A (p.Arg347Gln)	rs141288626	0.00007
NM_181882.3(PRX):c.922A>G (p.Thr308Ala)	rs753330520	0.00007
NM_181882.3(PRX):c.1100C>A (p.Ala367Asp)	rs143400291	0.00006
NM_181882.3(PRX):c.1479G>C (p.Glu493Asp)	rs367946424	0.00006
NM_181882.3(PRX):c.2701G>A (p.Val901Ile)	rs767898499	0.00006
NM_181882.3(PRX):c.3886G>C (p.Gly1296Arg)	rs769014032	0.00006
NM_181882.3(PRX):c.4112G>A (p.Arg1371Gln)	rs377009047	0.00006
NM_181882.3(PRX):c.4307G>A (p.Arg1436Gln)	rs368827070	0.00006
NM_181882.3(PRX):c.727G>A (p.Gly243Arg)	rs774726424	0.00006
NM_181882.3(PRX):c.839C>T (p.Pro280Leu)	rs557355077	0.00006
NM_181882.3(PRX):c.1837G>A (p.Val613Met)	rs773222045	0.00005
NM_181882.3(PRX):c.3239G>A (p.Arg1080His)	rs762213719	0.00005
NM_181882.3(PRX):c.3422C>T (p.Ala1141Val)	rs201233076	0.00005
NM_181882.3(PRX):c.4244_4246dup (p.Val1415_Ser1416insLeu)	rs771234852	0.00005
NM_181882.3(PRX):c.848T>G (p.Val283Gly)	rs776556523	0.00005
NM_181882.3(PRX):c.1222C>T (p.Pro408Ser)	rs150244426	0.00004
NM_181882.3(PRX):c.1391G>A (p.Arg464Gln)	rs553211374	0.00004
NM_181882.3(PRX):c.2384T>C (p.Met795Thr)	rs756958051	0.00004
NM_181882.3(PRX):c.2464G>A (p.Glu822Lys)	rs772009400	0.00004
NM_181882.3(PRX):c.2620G>A (p.Ala874Thr)	rs145790961	0.00004
NM_181882.3(PRX):c.2690G>A (p.Arg897Gln)	rs752531623	0.00004
NM_181882.3(PRX):c.3845C>T (p.Ser1282Leu)	rs753530396	0.00004
NM_181882.3(PRX):c.4349C>T (p.Pro1450Leu)	rs369949312	0.00004
NM_181882.3(PRX):c.625G>A (p.Ala209Thr)	rs769143653	0.00004
NM_181882.3(PRX):c.1752G>C (p.Glu584Asp)	rs759029769	0.00003
NM_181882.3(PRX):c.2450G>A (p.Arg817His)	rs149241078	0.00003
NM_181882.3(PRX):c.2816C>T (p.Ser939Leu)	rs761769929	0.00003
NM_181882.3(PRX):c.3041T>C (p.Leu1014Pro)	rs766119564	0.00003
NM_181882.3(PRX):c.4157C>A (p.Pro1386His)	rs372582520	0.00003
NM_181882.3(PRX):c.4334C>T (p.Thr1445Ile)	rs746338096	0.00003
NM_181882.3(PRX):c.716C>T (p.Pro239Leu)	rs528907584	0.00003
NM_181882.3(PRX):c.847G>A (p.Val283Met)	rs535087433	0.00003
NM_181882.3(PRX):c.899T>C (p.Leu300Ser)	rs748380935	0.00003
NM_181882.3(PRX):c.2306C>T (p.Pro769Leu)	rs371887816	0.00002
NM_181882.3(PRX):c.3646G>A (p.Val1216Met)	rs774413102	0.00002
NM_181882.3(PRX):c.4117C>T (p.Arg1373Trp)	rs766729202	0.00002
NM_181882.3(PRX):c.1019C>T (p.Pro340Leu)	rs780373582	0.00001
NM_181882.3(PRX):c.1170A>T (p.Arg390Ser)	rs1288181008	0.00001
NM_181882.3(PRX):c.13A>G (p.Ser5Gly)	rs767350599	0.00001
NM_181882.3(PRX):c.1441G>T (p.Val481Leu)	rs747179548	0.00001
NM_181882.3(PRX):c.1490C>T (p.Pro497Leu)	rs1167411868	0.00001
NM_181882.3(PRX):c.1797A>T (p.Lys599Asn)	rs757931043	0.00001
NM_181882.3(PRX):c.1925C>T (p.Pro642Leu)	rs751935470	0.00001
NM_181882.3(PRX):c.2252C>T (p.Ser751Leu)	rs570569581	0.00001
NM_181882.3(PRX):c.2681T>A (p.Val894Glu)	rs778360076	0.00001
NM_181882.3(PRX):c.3275T>G (p.Val1092Gly)	rs202065092	0.00001
NM_181882.3(PRX):c.3440C>T (p.Pro1147Leu)	rs748957380	0.00001
NM_181882.3(PRX):c.3640C>T (p.Pro1214Ser)	rs1303392170	0.00001
NM_181882.3(PRX):c.3772G>T (p.Gly1258Cys)	rs781392383	0.00001
NM_181882.3(PRX):c.3928C>T (p.Arg1310Trp)	rs751126995	0.00001
NM_181882.3(PRX):c.4109G>A (p.Arg1370His)	rs756687548	0.00001
NM_181882.3(PRX):c.4232G>T (p.Arg1411Leu)	rs1005254872	0.00001
NM_181882.3(PRX):c.4335_4336del (p.Ala1447fs)	rs778270475	0.00001
NM_181882.3(PRX):c.707T>C (p.Leu236Pro)	rs876661240	0.00001
NM_181882.3(PRX):c.994A>G (p.Thr332Ala)	rs143710873	0.00001
NM_181882.3(PRX):c.-242-3T>G
NM_181882.3(PRX):c.1012G>C (p.Ala338Pro)
NM_181882.3(PRX):c.1087C>T (p.Pro363Ser)	rs886054439
NM_181882.3(PRX):c.1134C>T (p.Ala378=)
NM_181882.3(PRX):c.1483_1560del (p.469ELPKVSEMKLPKVPEMAVPEVRLPEV[1])	rs1555801137
NM_181882.3(PRX):c.1490_1567del (p.Pro497_Leu522del)
NM_181882.3(PRX):c.1523C>T (p.Pro508Leu)
NM_181882.3(PRX):c.1568_1645del (p.Leu523_Leu548del)
NM_181882.3(PRX):c.164G>A (p.Arg55Lys)	rs773586301
NM_181882.3(PRX):c.1658A>G (p.Glu553Gly)	rs879254301
NM_181882.3(PRX):c.1791G>A (p.Glu597=)
NM_181882.3(PRX):c.1805A>C (p.Glu602Ala)	rs2079439386
NM_181882.3(PRX):c.1825C>T (p.Pro609Ser)	rs759927281
NM_181882.3(PRX):c.1900A>G (p.Met634Val)	rs201204029
NM_181882.3(PRX):c.1900_1914del (p.629MKLPE[1])	rs575492732
NM_181882.3(PRX):c.1911_1925del (p.Glu638_Pro642del)	rs759376968
NM_181882.3(PRX):c.1936G>C (p.Glu646Gln)	rs750625856
NM_181882.3(PRX):c.2097G>A (p.Met699Ile)	rs886042156
NM_181882.3(PRX):c.2215G>A (p.Asp739Asn)	rs779294844
NM_181882.3(PRX):c.2230G>A (p.Glu744Lys)	rs2145728884
NM_181882.3(PRX):c.2243C>G (p.Pro748Arg)	rs111252437
NM_181882.3(PRX):c.2261G>A (p.Arg754Gln)	rs760071236
NM_181882.3(PRX):c.2282_2284del (p.Pro761_Lys762delinsGln)	rs1131691425
NM_181882.3(PRX):c.2300A>G (p.His767Arg)	rs760124085
NM_181882.3(PRX):c.232_233delinsAC (p.Glu78Thr)
NM_181882.3(PRX):c.2383A>G (p.Met795Val)
NM_181882.3(PRX):c.2404_2412del (p.Pro802_Met804del)
NM_181882.3(PRX):c.265C>T (p.Pro89Ser)	rs550049072
NM_181882.3(PRX):c.2812C>T (p.Leu938Phe)
NM_181882.3(PRX):c.281_283del (p.Phe94del)	rs1424434006
NM_181882.3(PRX):c.3106G>A (p.Ala1036Thr)	rs1599651692
NM_181882.3(PRX):c.3190C>T (p.Pro1064Ser)	rs937051533
NM_181882.3(PRX):c.3527CAG[1] (p.Ala1177del)	rs765351391
NM_181882.3(PRX):c.3558G>C (p.Gln1186His)
NM_181882.3(PRX):c.3638T>C (p.Met1213Thr)
NM_181882.3(PRX):c.3705G>C (p.Glu1235Asp)
NM_181882.3(PRX):c.3718G>A (p.Glu1240Lys)
NM_181882.3(PRX):c.3722G>A (p.Gly1241Asp)	rs139120811
NM_181882.3(PRX):c.3766G>C (p.Val1256Leu)	rs1599650451
NM_181882.3(PRX):c.381+24_381+39dup
NM_181882.3(PRX):c.381+41G>A
NM_181882.3(PRX):c.3873C>G (p.Tyr1291Ter)	rs765769524
NM_181882.3(PRX):c.3961G>A (p.Glu1321Lys)	rs748063094
NM_181882.3(PRX):c.4059GGA[8] (p.Glu1361dup)	rs139624657
NM_181882.3(PRX):c.4207G>A (p.Val1403Ile)	rs139051512
NM_181882.3(PRX):c.4243G>A (p.Val1415Met)	rs201222650
NM_181882.3(PRX):c.4283A>C (p.Gln1428Pro)	rs2145724629
NM_181882.3(PRX):c.4352C>T (p.Ala1451Val)	rs2145724458
NM_181882.3(PRX):c.4366G>T (p.Ala1456Ser)	rs149093940
NM_181882.3(PRX):c.464A>T (p.Asp155Val)	rs2079458431
NM_181882.3(PRX):c.485A>G (p.Lys162Arg)	rs879254072
NM_181882.3(PRX):c.631G>A (p.Ala211Thr)	rs112973322
NM_181882.3(PRX):c.682C>G (p.Arg228Gly)	rs751238438
NM_181882.3(PRX):c.682C>T (p.Arg228Cys)	rs751238438
NM_181882.3(PRX):c.7G>A (p.Ala3Thr)
NM_181882.3(PRX):c.832_861del (p.Pro278_Ala287del)	rs2079451762

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