List of variants in gene WWOX reported as uncertain significance for not provided

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 105

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HGVS	dbSNP	gnomAD frequency
NM_016373.4(WWOX):c.816G>T (p.Leu272Phe)	rs186745328	0.00280
NM_016373.4(WWOX):c.935C>A (p.Ser312Tyr)	rs79399971	0.00038
NM_016373.4(WWOX):c.998G>A (p.Arg333His)	rs184773837	0.00036
NM_016373.4(WWOX):c.713A>G (p.Tyr238Cys)	rs142806268	0.00026
NM_016373.4(WWOX):c.928C>T (p.Arg310Cys)	rs193001955	0.00024
NM_016373.4(WWOX):c.301C>G (p.Pro101Ala)	rs574637594	0.00016
NM_016373.4(WWOX):c.990C>G (p.Asn330Lys)	rs117209694	0.00016
NM_016373.4(WWOX):c.499C>T (p.Arg167Cys)	rs201228765	0.00014
NM_016373.4(WWOX):c.898A>G (p.Asn300Asp)	rs374541202	0.00012
NM_016373.4(WWOX):c.591C>G (p.Phe197Leu)	rs200847456	0.00011
NM_016373.4(WWOX):c.851A>G (p.Lys284Arg)	rs897453553	0.00010
NM_016373.4(WWOX):c.406A>G (p.Ile136Val)	rs193027041	0.00009
NM_016373.4(WWOX):c.482C>T (p.Ala161Val)	rs369055872	0.00009
NM_016373.4(WWOX):c.981G>A (p.Met327Ile)	rs758307666	0.00007
NM_016373.4(WWOX):c.421G>A (p.Ala141Thr)	rs369907002	0.00006
NM_016373.4(WWOX):c.958G>A (p.Ala320Thr)	rs368670215	0.00006
NM_016373.4(WWOX):c.214C>G (p.Gln72Glu)	rs201008667	0.00004
NM_016373.4(WWOX):c.322G>A (p.Asp108Asn)	rs747575799	0.00004
NM_016373.4(WWOX):c.410G>A (p.Gly137Glu)	rs761879076	0.00004
NM_016373.4(WWOX):c.605T>G (p.Val202Gly)	rs112636835	0.00004
NM_016373.4(WWOX):c.673C>G (p.Leu225Val)	rs376040091	0.00004
NM_016373.4(WWOX):c.760C>T (p.Arg254Cys)	rs369715848	0.00004
NM_016373.4(WWOX):c.926G>A (p.Arg309His)	rs370792938	0.00004
NM_016373.4(WWOX):c.251C>G (p.Thr84Ser)	rs757145186	0.00003
NM_016373.4(WWOX):c.563G>A (p.Arg188His)	rs771163284	0.00003
NM_016373.4(WWOX):c.746G>A (p.Arg249His)	rs756703833	0.00003
NM_016373.4(WWOX):c.439C>T (p.His147Tyr)	rs746480783	0.00002
NM_016373.4(WWOX):c.658C>G (p.Leu220Val)	rs770774574	0.00002
NM_016373.4(WWOX):c.697C>A (p.His233Asn)	rs757863128	0.00002
NM_016373.4(WWOX):c.997C>T (p.Arg333Cys)	rs369281766	0.00002
NM_016373.4(WWOX):c.1019T>C (p.Leu340Pro)	rs761125565	0.00001
NM_016373.4(WWOX):c.1026T>G (p.Phe342Leu)	rs1322358404	0.00001
NM_016373.4(WWOX):c.119A>G (p.Glu40Gly)	rs778346490	0.00001
NM_016373.4(WWOX):c.193C>A (p.Gln65Lys)	rs558101281	0.00001
NM_016373.4(WWOX):c.287A>G (p.Asp96Gly)	rs776969977	0.00001
NM_016373.4(WWOX):c.51G>T (p.Glu17Asp)	rs991773402	0.00001
NM_016373.4(WWOX):c.524C>T (p.Ala175Val)	rs1131691324	0.00001
NM_016373.4(WWOX):c.538A>G (p.Met180Val)	rs569297468	0.00001
NM_016373.4(WWOX):c.566G>A (p.Ser189Asn)	rs776354746	0.00001
NM_016373.4(WWOX):c.59C>T (p.Pro20Leu)	rs761638116	0.00001
NM_016373.4(WWOX):c.605+5G>A	rs1039151413	0.00001
NM_016373.4(WWOX):c.631G>A (p.Ala211Thr)	rs370737224	0.00001
NM_016373.4(WWOX):c.647T>C (p.Leu216Pro)	rs1385370021	0.00001
NM_016373.4(WWOX):c.691G>C (p.Val231Leu)	rs755974419	0.00001
NM_016373.4(WWOX):c.708C>G (p.His236Gln)	rs745681407	0.00001
NM_016373.4(WWOX):c.737T>C (p.Val246Ala)	rs200966505	0.00001
NM_016373.4(WWOX):c.818G>A (p.Gly273Glu)	rs756228469	0.00001
NM_016373.4(WWOX):c.82A>C (p.Lys28Gln)	rs771726317	0.00001
NM_016373.4(WWOX):c.940C>T (p.Arg314Cys)	rs781683643	0.00001
GRCh37/hg19 16q23.1(chr16:78080329-78325545)x3
GRCh37/hg19 16q23.1(chr16:78103821-78334723)x3
GRCh37/hg19 16q23.1(chr16:78112284-78183613)x3
GRCh37/hg19 16q23.1(chr16:78180603-78236617)x1
GRCh37/hg19 16q23.1(chr16:78205565-78344587)x1
GRCh37/hg19 16q23.1(chr16:78229572-78687523)x1
GRCh37/hg19 16q23.1(chr16:78296293-78426119)x1
GRCh37/hg19 16q23.1(chr16:78298421-78473829)x3
GRCh37/hg19 16q23.1(chr16:78308767-78367613)x1
GRCh37/hg19 16q23.1(chr16:78308940-78367613)x1
GRCh37/hg19 16q23.1(chr16:78372426-78426119)x1
GRCh37/hg19 16q23.1(chr16:78372597-78504169)x1
GRCh37/hg19 16q23.1(chr16:78372847-78466128)x1
GRCh37/hg19 16q23.1(chr16:78384725-78508065)x1
GRCh37/hg19 16q23.1(chr16:78420576-78519780)x1
GRCh37/hg19 16q23.1(chr16:78454450-78466097)x1
GRCh37/hg19 16q23.1(chr16:78469169-78739257)x1
GRCh37/hg19 16q23.1(chr16:78520848-78630819)x1
GRCh37/hg19 16q23.1-23.2(chr16:79031223-79456467)x3
GRCh37/hg19 16q23.1-23.2(chr16:79031223-79456816)x3
NM_016373.4(WWOX):c.-460C>T
NM_016373.4(WWOX):c.1039C>G (p.Pro347Ala)	rs200699154
NM_016373.4(WWOX):c.1039C>T (p.Pro347Ser)
NM_016373.4(WWOX):c.1044C>A (p.Phe348Leu)	rs1057524658
NM_016373.4(WWOX):c.1047C>G (p.Thr349=)
NM_016373.4(WWOX):c.11T>G (p.Leu4Arg)
NM_016373.4(WWOX):c.161G>A (p.Arg54Gln)	rs543154053
NM_016373.4(WWOX):c.189G>C (p.Trp63Cys)	rs1265607632
NM_016373.4(WWOX):c.253T>G (p.Tyr85Asp)	rs781063964
NM_016373.4(WWOX):c.28G>T (p.Asp10Tyr)	rs781180473
NM_016373.4(WWOX):c.310C>T (p.Arg104Trp)	rs750226191
NM_016373.4(WWOX):c.341T>C (p.Met114Thr)	rs761906386
NM_016373.4(WWOX):c.416A>C (p.Glu139Ala)	rs2151735391
NM_016373.4(WWOX):c.454A>G (p.Ile152Val)	rs961514796
NM_016373.4(WWOX):c.476C>G (p.Ala159Gly)	rs2034894480
NM_016373.4(WWOX):c.535G>T (p.Ala179Ser)	rs11545029
NM_016373.4(WWOX):c.562C>A (p.Arg188Ser)	rs199511589
NM_016373.4(WWOX):c.562C>T (p.Arg188Cys)	rs199511589
NM_016373.4(WWOX):c.641T>C (p.Phe214Ser)	rs1474238209
NM_016373.4(WWOX):c.688C>G (p.Gln230Glu)	rs1057524749
NM_016373.4(WWOX):c.700C>A (p.Leu234Met)
NM_016373.4(WWOX):c.711C>G (p.Phe237Leu)	rs769589145
NM_016373.4(WWOX):c.733G>A (p.Asp245Asn)
NM_016373.4(WWOX):c.745C>A (p.Arg249Ser)	rs749277249
NM_016373.4(WWOX):c.745C>T (p.Arg249Cys)	rs749277249
NM_016373.4(WWOX):c.766A>T (p.Ile256Phe)	rs1023419687
NM_016373.4(WWOX):c.767T>C (p.Ile256Thr)	rs775895501
NM_016373.4(WWOX):c.782A>G (p.Glu261Gly)	rs1464495960
NM_016373.4(WWOX):c.7G>A (p.Ala3Thr)	rs1336300148
NM_016373.4(WWOX):c.856G>A (p.Asp286Asn)	rs374658336
NM_016373.4(WWOX):c.856G>T (p.Asp286Tyr)	rs374658336
NM_016373.4(WWOX):c.935C>T (p.Ser312Phe)	rs79399971
NM_016373.4(WWOX):c.965A>G (p.His322Arg)	rs878855022
NM_016373.4(WWOX):c.968C>G (p.Pro323Arg)	rs1567570468
NM_016373.4(WWOX):c.978G>C (p.Met326Ile)	rs748074874
NM_016373.4(WWOX):c.981G>C (p.Met327Ile)	rs758307666

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