List of variants in gene APC studied for Hereditary cancer

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
		ClinVar version:

Total variants: 16

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_000038.6(APC):c.3173A>G (p.Asp1058Gly)	rs148725540	0.00056
NM_000038.6(APC):c.6857C>T (p.Ala2286Val)	rs200587641	0.00036
NM_000038.6(APC):c.2593C>T (p.Pro865Ser)	rs192620988	0.00028
NM_000038.6(APC):c.6637A>G (p.Met2213Val)	rs186926737	0.00018
NM_000038.6(APC):c.3625G>A (p.Glu1209Lys)	rs201185479	0.00005
NM_000038.6(APC):c.4372C>T (p.Pro1458Ser)	rs143796828	0.00005
NM_000038.6(APC):c.647G>A (p.Arg216Gln)	rs76685252	0.00003
NM_000038.6(APC):c.5308A>G (p.Lys1770Glu)	rs551183536	0.00002
NM_000038.6(APC):c.7495G>C (p.Val2499Leu)	rs33941929	0.00002
NM_000038.6(APC):c.7550A>G (p.Tyr2517Cys)	rs587783036	0.00002
NM_000038.6(APC):c.1580G>C (p.Arg527Thr)	rs1554081889	0.00001
NM_000038.6(APC):c.2642C>T (p.Ser881Phe)	rs535344579	0.00001
NM_000038.6(APC):c.5017G>A (p.Glu1673Lys)	rs587779796	0.00001
NM_000038.6(APC):c.278T>A (p.Leu93His)	rs876658977
NM_000038.6(APC):c.4765C>G (p.Arg1589Gly)	rs72541813
NM_000038.6(APC):c.7391C>G (p.Ser2464Cys)	rs766473931

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.