List of variants in gene APC reported as uncertain significance by Genetic Services Laboratory, University of Chicago

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 34

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HGVS	dbSNP	gnomAD frequency
NM_000038.6(APC):c.8266A>G (p.Ile2756Val)	rs146115809	0.00026
NM_000038.6(APC):c.7036C>T (p.Pro2346Ser)	rs200756935	0.00022
NM_000038.6(APC):c.5009C>T (p.Ala1670Val)	rs202228932	0.00018
NM_000038.6(APC):c.5801C>T (p.Pro1934Leu)	rs587780600	0.00012
NM_000038.6(APC):c.277C>G (p.Leu93Val)	rs201567345	0.00011
NM_000038.6(APC):c.4918C>T (p.Arg1640Trp)	rs373440614	0.00010
NM_000038.6(APC):c.4072G>A (p.Ala1358Thr)	rs139618756	0.00006
NM_000038.6(APC):c.5026A>G (p.Arg1676Gly)	rs370560998	0.00006
NM_000038.6(APC):c.5140G>A (p.Asp1714Asn)	rs148275069	0.00006
NM_000038.6(APC):c.7399C>A (p.Pro2467Thr)	rs372305287	0.00006
NM_000038.6(APC):c.3368A>C (p.Gln1123Pro)	rs587779789	0.00004
NM_000038.6(APC):c.4395T>A (p.Ser1465Arg)	rs779898882	0.00004
NM_000038.6(APC):c.7415C>T (p.Ala2472Val)	rs200399245	0.00003
NM_000038.6(APC):c.3689A>G (p.Gln1230Arg)	rs764706774	0.00002
NM_000038.6(APC):c.835-3T>C	rs372090940	0.00002
NM_000038.6(APC):c.1243G>A (p.Ala415Thr)	rs756336949	0.00001
NM_000038.6(APC):c.3163A>G (p.Ile1055Val)	rs1580631854	0.00001
NM_000038.6(APC):c.3323A>G (p.Asn1108Ser)	rs151286353	0.00001
NM_000038.6(APC):c.3415A>C (p.Lys1139Gln)	rs201550951	0.00001
NM_000038.6(APC):c.3653C>T (p.Thr1218Met)	rs377640390	0.00001
NM_000038.6(APC):c.3824G>C (p.Ser1275Thr)	rs587781637	0.00001
NM_000038.6(APC):c.3964G>A (p.Glu1322Lys)	rs752926571	0.00001
NM_000038.6(APC):c.5194A>G (p.Met1732Val)	rs752065261	0.00001
NM_000038.6(APC):c.8378G>A (p.Ser2793Asn)	rs374853436	0.00001
NM_000038.6(APC):c.2621C>T (p.Ser874Leu)	rs1554084318
NM_000038.6(APC):c.2941C>T (p.Pro981Ser)	rs2149880710
NM_000038.6(APC):c.396A>G (p.Gly132=)	rs1060504884
NM_000038.6(APC):c.4765C>G (p.Arg1589Gly)	rs72541813
NM_000038.6(APC):c.4765C>T (p.Arg1589Cys)	rs72541813
NM_000038.6(APC):c.4993C>G (p.Pro1665Ala)	rs1561596883
NM_000038.6(APC):c.5840C>G (p.Thr1947Ser)	rs575724078
NM_000038.6(APC):c.6354TGC[5] (p.Ala2122dup)	rs587780602
NM_000038.6(APC):c.6820G>A (p.Ala2274Thr)	rs2149974011
NM_000038.6(APC):c.7037C>T (p.Pro2346Leu)	rs2149978691

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