List of variants in gene APC reported as uncertain significance by CeGaT Center for Human Genetics Tuebingen

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 36

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HGVS	dbSNP	gnomAD frequency
NM_000038.6(APC):c.7490C>T (p.Ser2497Leu)	rs141010008	0.00031
NM_000038.6(APC):c.5009C>T (p.Ala1670Val)	rs202228932	0.00018
NM_000038.6(APC):c.5879C>T (p.Pro1960Leu)	rs587781546	0.00005
NM_000038.6(APC):c.2627G>A (p.Arg876Gln)	rs373428732	0.00004
NM_000038.6(APC):c.7402T>C (p.Ser2468Pro)	rs375586273	0.00004
NM_000038.6(APC):c.379A>G (p.Ser127Gly)	rs200089324	0.00003
NM_000038.6(APC):c.2240C>T (p.Ser747Leu)	rs773020689	0.00002
NM_000038.6(APC):c.262C>T (p.Arg88Trp)	rs746592911	0.00001
NM_000038.6(APC):c.2768G>C (p.Arg923Thr)	rs1057519194	0.00001
NM_000038.6(APC):c.2958T>C (p.Tyr986=)	rs746581330	0.00001
NM_000038.6(APC):c.365G>T (p.Gly122Val)	rs755660899	0.00001
NM_000038.6(APC):c.5302A>G (p.Lys1768Glu)	rs199630012	0.00001
NM_000038.6(APC):c.6196A>G (p.Arg2066Gly)	rs786204043	0.00001
NM_000038.6(APC):c.688C>T (p.Arg230Cys)	rs587779805	0.00001
NM_000038.6(APC):c.6974G>A (p.Gly2325Asp)	rs1554087886	0.00001
NM_000038.6(APC):c.8399C>T (p.Ala2800Val)	rs141024271	0.00001
NM_000038.6(APC):c.1333C>G (p.Gln445Glu)	rs876658802
NM_000038.6(APC):c.1688T>C (p.Leu563Ser)	rs1580574619
NM_000038.6(APC):c.1813G>A (p.Asp605Asn)	rs1060503278
NM_000038.6(APC):c.2819C>T (p.Ser940Leu)	rs544709767
NM_000038.6(APC):c.2834_2835delinsTT (p.Arg945Ile)	rs786204162
NM_000038.6(APC):c.3084T>G (p.Ser1028Arg)	rs876660265
NM_000038.6(APC):c.3193C>A (p.Gln1065Lys)	rs1330361513
NM_000038.6(APC):c.423-33_423-17del
NM_000038.6(APC):c.4538A>C (p.Glu1513Ala)
NM_000038.6(APC):c.4898C>A (p.Thr1633Lys)	rs765215625
NM_000038.6(APC):c.4940C>A (p.Thr1647Lys)
NM_000038.6(APC):c.5490T>G (p.Asn1830Lys)	rs1554086766
NM_000038.6(APC):c.5573G>T (p.Arg1858Leu)	rs369831474
NM_000038.6(APC):c.5628G>T (p.Arg1876Ser)	rs1064794942
NM_000038.6(APC):c.608A>G (p.Gln203Arg)	rs1554072626
NM_000038.6(APC):c.6285T>C (p.Asp2095=)	rs1580669392
NM_000038.6(APC):c.6386C>T (p.Ser2129Leu)	rs587782301
NM_000038.6(APC):c.7696A>C (p.Arg2566=)	rs1060504883
NM_000038.6(APC):c.7892C>T (p.Ser2631Phe)	rs730881269
NM_001127511.3(APC):c.-140C>G	rs775297664

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