List of variants in gene APC reported as uncertain significance by ClinGen InSiGHT Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 14

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HGVS	dbSNP	gnomAD frequency
NC_000005.9:g.(?_112116481)_(112179829_?)dup
NM_000038.6(APC):c.1105TTG[1] (p.Leu370del)	rs1580529312
NM_000038.6(APC):c.1627G>T (p.Val543Phe)	rs1554082080
NM_000038.6(APC):c.3077A>C (p.Asn1026Thr)	rs1114167603
NM_000038.6(APC):c.3083G>A (p.Ser1028Asn)	rs1114167617
NM_000038.6(APC):c.3084T>G (p.Ser1028Arg)	rs876660265
NM_000038.6(APC):c.32dup (p.Gln12fs)	rs1561444620
NM_000038.6(APC):c.423-3_423-2del	rs863225354
NM_000038.6(APC):c.4732T>G (p.Cys1578Gly)	rs138367627
NM_000038.6(APC):c.5761G>A (p.Gly1921Ser)	rs1060503324
NM_000038.6(APC):c.6796_6810del (p.Thr2266_Ser2270del)	rs1057517569
NM_000038.6(APC):c.754A>G (p.Thr252Ala)	rs1580454642
NM_000038.6(APC):c.8514C>A (p.Tyr2838Ter)	rs876660375
NM_000038.6(APC):c.8530T>G (p.Ter2844Glu)	rs1766772190

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