List of variants in gene APOB reported as likely benign by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 77

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HGVS	dbSNP	gnomAD frequency
NM_000384.3(APOB):c.905-15C>G	rs72653061	0.00554
NM_000384.3(APOB):c.12794T>C (p.Val4265Ala)	rs61743502	0.00516
NM_000384.3(APOB):c.607A>G (p.Ile203Val)	rs72653059	0.00396
NM_000384.3(APOB):c.6261C>A (p.Thr2087=)	rs61744855	0.00366
NM_000384.3(APOB):c.3383G>A (p.Arg1128His)	rs12713843	0.00356
NM_000384.3(APOB):c.7696G>A (p.Glu2566Lys)	rs1801696	0.00305
NM_000384.3(APOB):c.8462C>T (p.Pro2821Leu)	rs72653095	0.00267
NM_000384.3(APOB):c.1785C>G (p.Ser595=)	rs139864087	0.00247
NM_000384.3(APOB):c.4825T>C (p.Leu1609=)	rs72653083	0.00242
NM_000384.3(APOB):c.2295G>A (p.Leu765=)	rs72653063	0.00235
NM_000384.3(APOB):c.11833A>G (p.Thr3945Ala)	rs1801698	0.00212
NM_000384.3(APOB):c.7615G>A (p.Val2539Ile)	rs148170480	0.00210
NM_000384.3(APOB):c.12766G>A (p.Glu4256Lys)	rs61743313	0.00198
NM_000384.3(APOB):c.751G>A (p.Ala251Thr)	rs61741625	0.00190
NM_000384.3(APOB):c.3426G>A (p.Ser1142=)	rs142448733	0.00177
NM_000384.3(APOB):c.905-16A>C	rs12720810	0.00172
NM_000384.3(APOB):c.9105T>C (p.Asn3035=)	rs147510760	0.00166
NM_000384.3(APOB):c.3279C>G (p.Thr1093=)	rs72653075	0.00163
NM_000384.3(APOB):c.11819C>T (p.Thr3940Met)	rs72654416	0.00161
NM_000384.3(APOB):c.9294C>T (p.Tyr3098=)	rs145777339	0.00139
NM_000384.3(APOB):c.12699G>A (p.Ser4233=)	rs56675344	0.00136
NM_000384.3(APOB):c.2068-4T>A	rs41291161	0.00108
NM_000384.3(APOB):c.7612C>T (p.Leu2538=)	rs72653093	0.00108
NM_000384.3(APOB):c.4838G>C (p.Ser1613Thr)	rs61742247	0.00093
NM_000384.3(APOB):c.3509-11C>T	rs200768300	0.00091
NM_000384.3(APOB):c.12903C>T (p.Asp4301=)	rs200145506	0.00090
NM_000384.3(APOB):c.9937C>A (p.Leu3313Ile)	rs146687604	0.00088
NM_000384.3(APOB):c.1470+15T>C	rs185550846	0.00078
NM_000384.3(APOB):c.3178T>C (p.Leu1060=)	rs72653073	0.00078
NM_000384.3(APOB):c.9477G>A (p.Lys3159=)	rs13306196	0.00073
NM_000384.3(APOB):c.641G>A (p.Arg214His)	rs146152405	0.00064
NM_000384.3(APOB):c.7152T>C (p.Val2384=)	rs72653090	0.00041
NM_000384.3(APOB):c.9855C>T (p.Ile3285=)	rs72654403	0.00041
NM_000384.3(APOB):c.2310C>T (p.Val770=)	rs72653064	0.00036
NM_000384.3(APOB):c.6136G>A (p.Val2046Ile)	rs72653084	0.00035
NM_000384.3(APOB):c.2853G>A (p.Glu951=)	rs151193347	0.00031
NM_000384.3(APOB):c.8912A>C (p.Asn2971Thr)	rs72653098	0.00026
NM_000384.3(APOB):c.2817-19T>G	rs72653069	0.00025
NM_000384.3(APOB):c.11820G>A (p.Thr3940=)	rs72654417	0.00024
NM_000384.3(APOB):c.8994C>T (p.Gly2998=)	rs139332237	0.00024
NM_000384.3(APOB):c.13020T>C (p.Tyr4340=)	rs141339310	0.00021
NM_000384.3(APOB):c.3507T>C (p.Tyr1169=)	rs141763789	0.00021
NM_000384.3(APOB):c.11354C>T (p.Thr3785Ile)	rs143710616	0.00019
NM_000384.3(APOB):c.12016G>A (p.Val4006Ile)	rs183117027	0.00019
NM_000384.3(APOB):c.12088-14T>C	rs182329513	0.00011
NM_000384.3(APOB):c.400G>T (p.Ala134Ser)	rs368321279	0.00010
NM_000384.3(APOB):c.2313G>A (p.Pro771=)	rs552986140	0.00009
NM_000384.3(APOB):c.1648G>C (p.Asp550His)	rs145862664	0.00006
NM_000384.3(APOB):c.2568C>T (p.Pro856=)	rs184556149	0.00006
NM_000384.3(APOB):c.3126G>A (p.Ala1042=)	rs547789079	0.00006
NM_000384.3(APOB):c.5652C>T (p.Asn1884=)	rs766106302	0.00006
NM_000384.3(APOB):c.10371C>T (p.Ser3457=)	rs139891446	0.00005
NM_000384.3(APOB):c.7575A>G (p.Gln2525=)	rs377302171	0.00005
NM_000384.3(APOB):c.3034G>A (p.Glu1012Lys)	rs575505383	0.00003
NM_000384.3(APOB):c.6513A>G (p.Leu2171=)	rs547853968	0.00003
NM_000384.3(APOB):c.12024C>T (p.Thr4008=)	rs145269223	0.00002
NM_000384.3(APOB):c.12088-17T>C	rs767133075	0.00001
NM_000384.3(APOB):c.12636T>C (p.Thr4212=)	rs772812955	0.00001
NM_000384.3(APOB):c.13154G>A (p.Arg4385His)	rs533755016	0.00001
NM_000384.3(APOB):c.1395C>T (p.Asp465=)	rs757609661	0.00001
NM_000384.3(APOB):c.2437-17C>T	rs764415047	0.00001
NM_000384.3(APOB):c.8112G>A (p.Ala2704=)	rs746758433	0.00001
NM_000384.3(APOB):c.818+14T>C	rs753032495	0.00001
NM_000384.3(APOB):c.8530C>T (p.Leu2844=)	rs1553383318	0.00001
NM_000384.3(APOB):c.10520G>C (p.Arg3507Pro)	rs201156840
NM_000384.3(APOB):c.11401T>A (p.Ser3801Thr)
NM_000384.3(APOB):c.11442C>G (p.Thr3814=)	rs72654408
NM_000384.3(APOB):c.11477C>T (p.Thr3826Met)
NM_000384.3(APOB):c.12940A>G (p.Ile4314Val)
NM_000384.3(APOB):c.13368C>A (p.Thr4456=)	rs1553382258
NM_000384.3(APOB):c.1903C>A (p.Arg635=)	rs548108916
NM_000384.3(APOB):c.3122-6G>A	rs72653071
NM_000384.3(APOB):c.3427C>T (p.Pro1143Ser)
NM_000384.3(APOB):c.3508+17_3508+18del	rs1553384473
NM_000384.3(APOB):c.5066G>A (p.Arg1689His)
NM_000384.3(APOB):c.7930A>C (p.Arg2644=)	rs1553383425
NM_000384.3(APOB):c.9378A>G (p.Leu3126=)	rs760776177

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