List of variants in gene APOB reported as likely benign by Molecular Diagnostic Laboratory for Inherited Cardiovascular Disease, Montreal Heart Institute

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 79

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HGVS	dbSNP	gnomAD frequency
NM_000384.3(APOB):c.2222C>A (p.Thr741Asn)	rs12714192	0.02253
NM_000384.3(APOB):c.5741A>G (p.Asn1914Ser)	rs1801699	0.01706
NM_000384.3(APOB):c.9880T>C (p.Ser3294Pro)	rs12720855	0.01525
NM_000384.3(APOB):c.7367C>A (p.Ala2456Asp)	rs12713675	0.01524
NM_000384.3(APOB):c.12697T>A (p.Ser4233Thr)	rs61743299	0.01522
NM_000384.3(APOB):c.3337G>C (p.Asp1113His)	rs12713844	0.00735
NM_000384.3(APOB):c.6895G>C (p.Asp2299His)	rs12713681	0.00709
NM_000384.3(APOB):c.10294C>G (p.Gln3432Glu)	rs1042023	0.00669
NM_000384.3(APOB):c.1594C>T (p.Arg532Trp)	rs13306194	0.00578
NM_000384.3(APOB):c.12382G>A (p.Val4128Met)	rs1801703	0.00562
NM_000384.3(APOB):c.12940A>G (p.Ile4314Val)	rs72654423	0.00557
NM_000384.3(APOB):c.12794T>C (p.Val4265Ala)	rs61743502	0.00516
NM_000384.3(APOB):c.8353A>C (p.Asn2785His)	rs2163204	0.00400
NM_000384.3(APOB):c.607A>G (p.Ile203Val)	rs72653059	0.00396
NM_000384.3(APOB):c.606A>T (p.Glu202Asp)	rs61746672	0.00387
NM_000384.3(APOB):c.3383G>A (p.Arg1128His)	rs12713843	0.00376
NM_000384.3(APOB):c.8462C>T (p.Pro2821Leu)	rs72653095	0.00267
NM_000384.3(APOB):c.10061C>G (p.Ala3354Gly)	rs61742331	0.00256
NM_000384.3(APOB):c.581C>T (p.Thr194Met)	rs13306198	0.00229
NM_000384.3(APOB):c.11833A>G (p.Thr3945Ala)	rs1801698	0.00212
NM_000384.3(APOB):c.7242A>C (p.Glu2414Asp)	rs72653091	0.00212
NM_000384.3(APOB):c.7615G>A (p.Val2539Ile)	rs148170480	0.00210
NM_000384.3(APOB):c.3427C>T (p.Pro1143Ser)	rs72653077	0.00198
NM_000384.3(APOB):c.9105T>C (p.Asn3035=)	rs147510760	0.00166
NM_000384.3(APOB):c.5066G>A (p.Arg1689His)	rs151009667	0.00137
NM_000384.3(APOB):c.11401T>A (p.Ser3801Thr)	rs12713540	0.00127
NM_000384.3(APOB):c.2068-4T>A	rs41291161	0.00108
NM_000384.3(APOB):c.4163G>A (p.Arg1388His)	rs13306187	0.00106
NM_000384.3(APOB):c.7612C>T (p.Leu2538=)	rs72653093	0.00102
NM_000384.3(APOB):c.3740A>G (p.Tyr1247Cys)	rs61741164	0.00067
NM_000384.3(APOB):c.7285T>A (p.Ser2429Thr)	rs72653092	0.00061
NM_000384.3(APOB):c.4663A>G (p.Ile1555Val)	rs141225768	0.00059
NM_000384.3(APOB):c.2436+102A>G	rs576999094	0.00042
NM_000384.3(APOB):c.9855C>T (p.Ile3285=)	rs72654403	0.00041
NM_000384.3(APOB):c.2310C>T (p.Val770=)	rs72653064	0.00035
NM_000384.3(APOB):c.12252T>C (p.Tyr4084=)	rs138157751	0.00034
NM_000384.3(APOB):c.2853G>A (p.Glu951=)	rs151193347	0.00034
NM_000384.3(APOB):c.9810C>T (p.Phe3270=)	rs138010392	0.00027
NM_000384.3(APOB):c.8912A>C (p.Asn2971Thr)	rs72653098	0.00026
NM_000384.3(APOB):c.5763A>G (p.Gly1921=)	rs141022509	0.00023
NM_000384.3(APOB):c.12016G>A (p.Val4006Ile)	rs183117027	0.00022
NM_000384.3(APOB):c.3507T>C (p.Tyr1169=)	rs141763789	0.00021
NM_000384.3(APOB):c.13444A>G (p.Ile4482Val)	rs142702699	0.00019
NM_000384.3(APOB):c.4371A>G (p.Ala1457=)	rs201206305	0.00013
NM_000384.3(APOB):c.1343C>T (p.Ala448Val)	rs148167725	0.00012
NM_000384.3(APOB):c.11542G>A (p.Ala3848Thr)	rs61743512	0.00011
NM_000384.3(APOB):c.13288T>A (p.Ser4430Thr)	rs72654426	0.00008
NM_000384.3(APOB):c.2841C>T (p.Thr947=)	rs72653070	0.00008
NM_000384.3(APOB):c.12736T>G (p.Phe4246Val)	rs200260789	0.00007
NM_000384.3(APOB):c.7998A>G (p.Val2666=)	rs1042006	0.00007
NM_000384.3(APOB):c.11319G>A (p.Lys3773=)	rs780811733	0.00004
NM_000384.3(APOB):c.6125T>C (p.Met2042Thr)	rs371224295	0.00004
NM_000384.3(APOB):c.3125C>T (p.Ala1042Val)	rs61741467	0.00003
NM_000384.3(APOB):c.4181A>G (p.Asp1394Gly)	rs769694008	0.00003
NM_000384.3(APOB):c.4590C>T (p.Thr1530=)	rs1420371568	0.00003
NM_000384.3(APOB):c.13377T>C (p.Asp4459=)	rs746353350	0.00002
NM_000384.3(APOB):c.690C>A (p.Gly230=)	rs151096846	0.00002
NM_000384.3(APOB):c.11361C>T (p.Pro3787=)	rs200979977	0.00001
NM_000384.3(APOB):c.12087+9C>T	rs1298785033	0.00001
NM_000384.3(APOB):c.1251G>C (p.Leu417=)	rs1248243388	0.00001
NM_000384.3(APOB):c.13488A>G (p.Arg4496=)	rs755251454	0.00001
NM_000384.3(APOB):c.1617+7T>C	rs374552390	0.00001
NM_000384.3(APOB):c.339G>C (p.Leu113=)	rs1367232226	0.00001
NM_000384.3(APOB):c.3692T>C (p.Ile1231Thr)	rs1663429897	0.00001
NM_000384.3(APOB):c.384-8_384-5del	rs1206070366	0.00001
NM_000384.3(APOB):c.4818C>T (p.Tyr1606=)	rs564437453	0.00001
NM_000384.3(APOB):c.8724C>T (p.Asn2908=)	rs755498745	0.00001
NM_000384.3(APOB):c.1071C>T (p.Gly357=)	rs769527337
NM_000384.3(APOB):c.11477C>T (p.Thr3826Met)	rs61744153
NM_000384.3(APOB):c.1310G>A (p.Arg437His)	rs142114415
NM_000384.3(APOB):c.1661C>T (p.Pro554Leu)	rs12714214
NM_000384.3(APOB):c.3122-6G>A	rs72653071
NM_000384.3(APOB):c.4066C>T (p.Leu1356=)
NM_000384.3(APOB):c.4140A>G (p.Thr1380=)	rs781016611
NM_000384.3(APOB):c.4162C>T (p.Arg1388Cys)	rs267599185
NM_000384.3(APOB):c.6636TGA[1] (p.Asp2213del)	rs541497967
NM_000384.3(APOB):c.7930A>C (p.Arg2644=)	rs1553383425
NM_000384.3(APOB):c.9242G>C (p.Ser3081Thr)	rs72653100
NM_000384.3(APOB):c.9471C>T (p.Gly3157=)	rs746031928

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