List of variants in gene APP reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 9

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HGVS	dbSNP	gnomAD frequency
NM_000484.4(APP):c.592T>C (p.Ser198Pro)	rs145081708	0.00043
NM_000484.4(APP):c.1299+4A>G	rs945993637	0.00001
NM_000484.4(APP):c.1651G>A (p.Val551Met)	rs761339914	0.00001
NM_000484.4(APP):c.1995G>C (p.Glu665Asp)	rs63750363	0.00001
NM_000484.4(APP):c.1076G>C (p.Arg359Pro)	rs1057524107
NM_000484.4(APP):c.1859C>T (p.Pro620Leu)
NM_000484.4(APP):c.1978A>T (p.Asn660Tyr)	rs770773038
NM_000484.4(APP):c.2011A>T (p.Met671Leu)	rs572842823
NM_000484.4(APP):c.2253G>C (p.Lys751Asn)	rs1381242897

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