List of variants in gene ATR reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 31

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HGVS	dbSNP	gnomAD frequency
NM_001184.4(ATR):c.3424A>G (p.Ser1142Gly)	rs149008479	0.00058
NM_001184.4(ATR):c.4351C>T (p.Arg1451Trp)	rs148064542	0.00041
NM_001184.4(ATR):c.6023G>T (p.Arg2008Leu)	rs145569221	0.00037
NM_001184.4(ATR):c.4405A>G (p.Thr1469Ala)	rs78895258	0.00036
NM_001184.4(ATR):c.289A>T (p.Ile97Phe)	rs138473993	0.00022
NM_001184.4(ATR):c.483A>G (p.Arg161=)	rs182268224	0.00021
NM_001184.4(ATR):c.5257A>G (p.Ile1753Val)	rs143806447	0.00021
NM_001184.4(ATR):c.1258C>G (p.Leu420Val)	rs377186178	0.00016
NM_001184.4(ATR):c.5572T>C (p.Cys1858Arg)	rs367898142	0.00013
NM_001184.4(ATR):c.437C>A (p.Thr146Lys)	rs368592452	0.00012
NM_001184.4(ATR):c.1359T>G (p.His453Gln)	rs202239914	0.00008
NM_001184.4(ATR):c.7667C>G (p.Thr2556Ser)	rs200490116	0.00007
NM_001184.4(ATR):c.7864T>C (p.Tyr2622His)	rs374127772	0.00007
NM_001184.4(ATR):c.3151C>T (p.Arg1051Cys)	rs367641692	0.00005
NM_001184.4(ATR):c.3945+2dup	rs537031994	0.00004
NM_001184.4(ATR):c.7471G>A (p.Val2491Ile)	rs556313656	0.00004
NM_001184.4(ATR):c.3335A>G (p.Asp1112Gly)	rs778004569	0.00003
NM_001184.4(ATR):c.1843G>A (p.Ala615Thr)	rs759350161	0.00002
NM_001184.4(ATR):c.4376A>G (p.Asn1459Ser)	rs144591613	0.00002
NM_001184.4(ATR):c.1285C>T (p.Pro429Ser)	rs764970007	0.00001
NM_001184.4(ATR):c.1543C>T (p.Arg515Cys)	rs371791554	0.00001
NM_001184.4(ATR):c.2615C>T (p.Thr872Ile)	rs760532237	0.00001
NM_001184.4(ATR):c.5900G>A (p.Gly1967Asp)	rs751198306	0.00001
NM_001184.4(ATR):c.637C>G (p.Leu213Val)	rs1333914311	0.00001
NM_001184.4(ATR):c.6775C>G (p.Leu2259Val)	rs2071133204	0.00001
NM_001184.4(ATR):c.1432G>C (p.Glu478Gln)	rs371017404
NM_001184.4(ATR):c.1848TCT[1] (p.Leu618del)	rs757490543
NM_001184.4(ATR):c.241C>G (p.Leu81Val)
NM_001184.4(ATR):c.3418A>G (p.Ser1140Gly)
NM_001184.4(ATR):c.379A>G (p.Ile127Val)	rs2108488719
NM_001184.4(ATR):c.5389T>C (p.Ser1797Pro)

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