ClinVar Miner

Variants in gene AXIN2

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
15 6 555 309 51 1 876

Condition and significance breakdown #

Total conditions: 11
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Oligodontia-colorectal cancer syndrome 12 4 510 229 36 0 766
not specified 0 0 13 139 32 0 177
not provided 0 1 111 2 11 1 125
Oligodontia-colorectal cancer syndrome; Carcinoma of colon 0 0 10 0 1 0 11
Hereditary cancer-predisposing syndrome 0 0 1 2 3 0 6
Oligodontia; Colorectal cancer 1 0 1 1 0 0 3
Carcinoma of colon 2 0 0 0 0 0 2
Colorectal cancer 0 0 0 1 0 0 1
Hirschsprung disease 0 1 0 0 0 0 1
Inborn genetic diseases 0 0 1 0 0 0 1
Non-syndromic oligodontia 1 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 20
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 11 4 488 201 29 0 733
GeneDx 0 1 112 133 25 0 271
Illumina Clinical Services Laboratory,Illumina 0 0 26 37 9 0 72
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic 0 0 6 8 12 0 26
Integrated Genetics/Laboratory Corporation of America 0 0 4 2 14 0 20
Fulgent Genetics 0 0 10 0 1 0 11
PreventionGenetics 0 0 0 0 9 0 9
OMIM 4 0 0 0 0 0 4
CSER_CC_NCGL; University of Washington Medical Center 1 0 1 2 0 0 4
Vantari Genetics 0 0 1 2 1 0 4
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 0 3 0 3
Molecular Oncology Laboratory,Hospital Clínico San Carlos 0 0 2 0 0 0 2
Genetic Services Laboratory, University of Chicago 0 0 0 1 0 0 1
Ambry Genetics 0 0 1 0 0 0 1
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 0 0 1 0 0 0 1
Department of Prosthodontics,Peking University School and Hospital of Stomatology 1 0 0 0 0 0 1
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 1 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Human Genomics Unit,Institute for molecular medicine Finland (FIMM) 0 1 0 0 0 0 1
University of Washington Department of Laboratory Medicine,University of Washington 0 0 0 1 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.