ClinVar Miner

Variants in gene AXIN2

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
43 13 1170 526 86 1 1737

Condition and significance breakdown #

Total conditions: 13
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Oligodontia-colorectal cancer syndrome 40 8 1105 399 66 0 1582
Hereditary cancer-predisposing syndrome 1 5 122 83 18 0 227
not provided 0 2 119 89 18 1 227
not specified 0 0 14 142 35 0 182
none provided 0 0 2 4 8 0 14
Oligodontia-colorectal cancer syndrome; Carcinoma of colon 0 0 10 0 1 0 11
Oligodontia; Colorectal cancer 1 0 1 1 0 0 3
Carcinoma of colon 2 0 0 0 0 0 2
Malignant tumor of breast 0 0 1 0 1 0 2
Colorectal cancer 0 0 0 1 0 0 1
Hirschsprung disease 0 1 0 0 0 0 1
Inborn genetic diseases 0 0 1 0 0 0 1
Non-syndromic oligodontia 1 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 27
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 40 7 1061 427 38 0 1573
GeneDx 0 1 112 142 32 0 287
Ambry Genetics 1 5 122 82 16 0 226
Illumina Clinical Services Laboratory,Illumina 0 0 55 13 49 0 117
Integrated Genetics/Laboratory Corporation of America 0 0 5 4 19 0 28
Mayo Clinic Laboratories, Mayo Clinic 0 0 6 8 12 0 26
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 0 0 2 4 8 0 14
CeGaT Praxis fuer Humangenetik Tuebingen 0 1 8 4 0 0 13
Fulgent Genetics,Fulgent Genetics 0 0 10 0 1 0 11
PreventionGenetics, PreventionGenetics 0 0 0 0 9 0 9
Baylor Genetics 0 0 8 0 0 0 8
Mendelics 0 0 2 2 1 0 5
Department of Pathology and Laboratory Medicine,Sinai Health System 0 0 4 1 0 0 5
OMIM 4 0 0 0 0 0 4
CSER _CC_NCGL, University of Washington 1 0 1 2 0 0 4
Vantari Genetics 0 0 1 2 1 0 4
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 0 3 0 3
Center of Medical Genetics and Primary Health Care 0 0 1 0 1 0 2
Molecular Oncology Laboratory,Hospital Clínico San Carlos 0 0 2 0 0 0 2
Genetic Services Laboratory, University of Chicago 0 0 0 1 0 0 1
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics 0 0 1 0 0 0 1
Department of Prosthodontics,Peking University School and Hospital of Stomatology 1 0 0 0 0 0 1
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 0 1 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Human Genomics Unit,Institute for molecular medicine Finland (FIMM) 0 1 0 0 0 0 1
Molecular Diagnostics Laboratory, M Health Fairview: University of Minnesota 0 1 0 0 0 0 1
University of Washington Department of Laboratory Medicine, University of Washington 0 0 0 1 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.