List of variants in gene BRCA1 reported as likely benign by Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 30

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HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.2814A>G (p.Pro938=)	rs80356851	0.00183
NM_007294.4(BRCA1):c.21C>T (p.Arg7=)	rs149402012	0.00165
NM_007294.4(BRCA1):c.1137T>G (p.Ile379Met)	rs56128296	0.00158
NM_007294.4(BRCA1):c.4113G>A (p.Gly1371=)	rs147448807	0.00150
NM_007294.4(BRCA1):c.2109A>G (p.Thr703=)	rs4986844	0.00147
NM_007294.4(BRCA1):c.4992C>T (p.Leu1664=)	rs142459158	0.00061
NM_007294.4(BRCA1):c.528G>A (p.Thr176=)	rs34545365	0.00024
NM_007294.4(BRCA1):c.4813T>C (p.Leu1605=)	rs80356833	0.00022
NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)	rs41286292	0.00011
NM_007294.4(BRCA1):c.2352G>A (p.Ser784=)	rs372017932	0.00009
NM_007294.4(BRCA1):c.1617G>A (p.Thr539=)	rs372002119	0.00006
NM_007294.4(BRCA1):c.2522G>A (p.Arg841Gln)	rs80357337	0.00006
NM_007294.4(BRCA1):c.5278-14C>G	rs80358105	0.00006
NM_007294.4(BRCA1):c.288C>T (p.Asp96=)	rs146085503	0.00004
NM_007294.4(BRCA1):c.75C>T (p.Pro25=)	rs80356839	0.00004
NM_007294.4(BRCA1):c.212+16A>G	rs1057522049	0.00002
NM_007294.4(BRCA1):c.5175A>G (p.Glu1725=)	rs191373374	0.00002
NM_007294.4(BRCA1):c.2393C>T (p.Pro798Leu)	rs876660005	0.00001
NM_007294.4(BRCA1):c.4314C>G (p.Ala1438=)	rs80356856	0.00001
NM_007294.4(BRCA1):c.4764T>C (p.Ala1588=)	rs753651115	0.00001
NM_007294.4(BRCA1):c.4776C>G (p.Asn1592Lys)	rs761925468	0.00001
NM_007294.4(BRCA1):c.1081T>G (p.Ser361Ala)	rs80356946
NM_007294.4(BRCA1):c.1525A>G (p.Thr509Ala)	rs1238203770
NM_007294.4(BRCA1):c.1643T>G (p.Ile548Ser)	rs2154432348
NM_007294.4(BRCA1):c.2232T>C (p.Ala744=)	rs4986846
NM_007294.4(BRCA1):c.3071G>A (p.Ser1024Asn)	rs757579891
NM_007294.4(BRCA1):c.5167A>G (p.Ile1723Val)	rs1426821558
NM_007294.4(BRCA1):c.5365G>T (p.Ala1789Ser)	rs80357078
NM_007294.4(BRCA1):c.671-12del	rs273902781
NM_007294.4(BRCA1):c.823G>A (p.Gly275Ser)	rs8176153

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