ClinVar Miner

Variants in gene combination BRCA2, LOC106721785

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
4 0 13 10 6 29

Condition and significance breakdown #

Total conditions: 6
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Condition pathogenic uncertain significance likely benign benign total
Hereditary breast and ovarian cancer syndrome 4 8 2 1 15
not specified 0 4 8 2 13
Breast-ovarian cancer, familial 2 0 1 0 6 7
Fanconi anemia 0 1 2 1 4
Hereditary cancer-predisposing syndrome 0 2 1 0 3
not provided 0 1 1 0 2

Submitter and significance breakdown #

Total submitters: 10
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Submitter pathogenic uncertain significance likely benign benign total
Invitae 4 5 0 0 9
GeneDx 0 1 7 0 8
Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) 0 0 0 6 6
Genetic Services Laboratory, University of Chicago 0 2 1 1 4
Illumina Clinical Services Laboratory,Illumina 0 1 2 1 4
Quest Diagnostics Nichols Institute San Juan Capistrano 0 3 0 0 3
Color 0 2 1 0 3
Mendelics 0 2 0 0 2
GeneKor MSA 0 0 0 2 2
Department of Pathology and Laboratory Medicine,Sinai Health System 0 0 1 0 1

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