List of variants in gene BRCA2 reported as likely pathogenic for Breast and/or ovarian cancer

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 31

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.8350C>T (p.Arg2784Trp)	rs80359075	0.00001
NM_000059.4(BRCA2):c.8351G>A (p.Arg2784Gln)	rs80359076	0.00001
NM_000059.3(BRCA2):c.9064delinsGG (p.Arg3022fs)	rs1566253262
NM_000059.4(BRCA2):c.1888dup (p.Thr630fs)	rs80359314
NM_000059.4(BRCA2):c.262_263del (p.Leu88fs)	rs276174825
NM_000059.4(BRCA2):c.2704dup (p.Ala902fs)	rs2072463288
NM_000059.4(BRCA2):c.2760del (p.Ile921fs)	rs80359346
NM_000059.4(BRCA2):c.3468dup (p.Glu1157Ter)	rs2137496891
NM_000059.4(BRCA2):c.3G>T (p.Met1Ile)	rs80358650
NM_000059.4(BRCA2):c.4003G>T (p.Glu1335Ter)	rs747070579
NM_000059.4(BRCA2):c.4076del (p.Thr1359fs)	rs80359424
NM_000059.4(BRCA2):c.4803dup (p.Lys1602Ter)	rs2072513173
NM_000059.4(BRCA2):c.517G>C (p.Gly173Arg)	rs397507768
NM_000059.4(BRCA2):c.5862_5863del (p.Ser1955fs)	rs786202700
NM_000059.4(BRCA2):c.6341del (p.Pro2114fs)
NM_000059.4(BRCA2):c.6514_6515del (p.Ser2172fs)	rs886040662
NM_000059.4(BRCA2):c.6643del (p.Tyr2215fs)	rs80359614
NM_000059.4(BRCA2):c.6938-2A>G	rs81002863
NM_000059.4(BRCA2):c.7008-1G>A	rs786204280
NM_000059.4(BRCA2):c.728_729del (p.Asn243fs)	rs1593890204
NM_000059.4(BRCA2):c.7471del (p.Gln2491fs)	rs886038170
NM_000059.4(BRCA2):c.7843_7844del (p.Ile2615fs)	rs886040867
NM_000059.4(BRCA2):c.7958T>C (p.Leu2653Pro)	rs80359022
NM_000059.4(BRCA2):c.8168A>T (p.Asp2723Val)	rs41293513
NM_000059.4(BRCA2):c.8327T>G (p.Leu2776Ter)	rs397507977
NM_000059.4(BRCA2):c.8486A>G (p.Gln2829Arg)	rs80359100
NM_000059.4(BRCA2):c.9004G>A (p.Glu3002Lys)	rs80359152
NM_000059.4(BRCA2):c.9281C>G (p.Ser3094Ter)	rs786204283
NM_000059.4(BRCA2):c.9289dup (p.Cys3097fs)	rs2137652215
NM_000059.4(BRCA2):c.9302T>G (p.Leu3101Arg)	rs28897758
NM_000059.4(BRCA2):c.9925G>T (p.Glu3309Ter)	rs80359251

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