List of variants in gene BRCA2 reported as uncertain significance by Biesecker Lab/Clinical Genomics Section, National Institutes of Health

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 25

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.1792A>G (p.Thr598Ala)	rs28897710	0.00182
NM_000059.4(BRCA2):c.125A>G (p.Tyr42Cys)	rs4987046	0.00158
NM_000059.4(BRCA2):c.3515C>T (p.Ser1172Leu)	rs80358600	0.00146
NM_000059.4(BRCA2):c.7504C>T (p.Arg2502Cys)	rs55716624	0.00100
NM_000059.4(BRCA2):c.5198C>T (p.Ser1733Phe)	rs55639415	0.00069
NM_000059.4(BRCA2):c.6853A>G (p.Ile2285Val)	rs56272235	0.00026
NM_000059.4(BRCA2):c.6322C>T (p.Arg2108Cys)	rs55794205	0.00019
NM_000059.4(BRCA2):c.1889C>T (p.Thr630Ile)	rs80358479	0.00012
NM_000059.4(BRCA2):c.6338A>G (p.Asn2113Ser)	rs80358874	0.00009
NM_000059.4(BRCA2):c.6325G>A (p.Val2109Ile)	rs79456940	0.00006
NM_000059.4(BRCA2):c.5552T>G (p.Ile1851Ser)	rs80358776	0.00005
NM_000059.4(BRCA2):c.1564G>C (p.Gly522Arg)	rs80358442	0.00003
NM_000059.4(BRCA2):c.3581G>A (p.Gly1194Asp)	rs28897721	0.00003
NM_000059.4(BRCA2):c.8917C>T (p.Arg2973Cys)	rs45469092	0.00003
NM_000059.4(BRCA2):c.4779A>C (p.Glu1593Asp)	rs80358703	0.00002
NM_000059.4(BRCA2):c.8687G>A (p.Arg2896His)	rs80359128	0.00002
NM_000059.4(BRCA2):c.10111A>G (p.Thr3371Ala)	rs80358393	0.00001
NM_000059.4(BRCA2):c.3562A>G (p.Ile1188Val)	rs202230438	0.00001
NM_000059.4(BRCA2):c.964A>C (p.Lys322Gln)	rs11571640	0.00001
NM_000059.4(BRCA2):c.1022G>T (p.Cys341Phe)	rs80358403
NM_000059.4(BRCA2):c.4593A>T (p.Lys1531Asn)	rs386833397
NM_000059.4(BRCA2):c.50C>T (p.Thr17Ile)	rs386833396
NM_000059.4(BRCA2):c.5554G>T (p.Val1852Phe)	rs80358777
NM_000059.4(BRCA2):c.5732A>T (p.Asp1911Val)	rs200943373
NM_000059.4(BRCA2):c.8941G>A (p.Glu2981Lys)	rs139052578

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