ClinVar Miner

List of variants in gene BRCA2 reported as uncertain significance by Mendelics

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Gene type:
ClinVar version:
Total variants: 177
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HGVS dbSNP
NM_000059.3(BRCA2):c.10250A>G (p.Tyr3417Cys) rs730881600
NM_000059.3(BRCA2):c.1343G>A (p.Arg448His) rs80358423
NM_000059.3(BRCA2):c.1714G>A (p.Val572Ile) rs587782713
NM_000059.3(BRCA2):c.1714G>C (p.Val572Leu) rs587782713
NM_000059.3(BRCA2):c.1793C>T (p.Thr598Ile) rs80358462
NM_000059.3(BRCA2):c.229A>G (p.Thr77Ala) rs80358500
NM_000059.3(BRCA2):c.2401A>G (p.Asn801Asp) rs765279896
NM_000059.3(BRCA2):c.2729A>G (p.His910Arg) rs760792501
NM_000059.3(BRCA2):c.2755G>A (p.Glu919Lys) rs431825298
NM_000059.3(BRCA2):c.2803G>C (p.Asp935His) rs28897716
NM_000059.3(BRCA2):c.2827A>G (p.Ile943Val) rs397507294
NM_000059.3(BRCA2):c.2946A>G (p.Ile982Met) rs80358541
NM_000059.3(BRCA2):c.3032C>G (p.Thr1011Arg) rs80358548
NM_000059.3(BRCA2):c.3245A>G (p.Lys1082Arg) rs80358569
NM_000059.3(BRCA2):c.3299A>T (p.Asn1100Ile) rs80358575
NM_000059.3(BRCA2):c.3321A>C (p.Gln1107His) rs397507306
NM_000059.3(BRCA2):c.3475T>C (p.Cys1159Arg) rs886037814
NM_000059.3(BRCA2):c.3539A>G (p.Lys1180Arg) rs28897720
NM_000059.3(BRCA2):c.375T>A (p.Asp125Glu) rs80358616
NM_000059.3(BRCA2):c.3861_3863TAA[1] (p.Asn1288del) rs276174837
NM_000059.3(BRCA2):c.4129A>G (p.Asn1377Asp) rs1593901487
NM_000059.3(BRCA2):c.4265A>T (p.Glu1422Val) rs1593901855
NM_000059.3(BRCA2):c.4306A>G (p.Ile1436Val) rs778282885
NM_000059.3(BRCA2):c.4454T>G (p.Ile1485Arg) rs1555283790
NM_000059.3(BRCA2):c.5059_5062del (p.Leu1687fs) rs1281993806
NM_000059.3(BRCA2):c.5182G>A (p.Asp1728Asn) rs80358744
NM_000059.3(BRCA2):c.5206C>G (p.Gln1736Glu) rs886037802
NM_000059.3(BRCA2):c.5207A>G (p.Gln1736Arg) rs1183489363
NM_000059.3(BRCA2):c.5414A>G (p.Asn1805Ser) rs80358765
NM_000059.3(BRCA2):c.5492T>C (p.Ile1831Thr) rs587782007
NM_000059.3(BRCA2):c.5590G>A (p.Asp1864Asn) rs587781536
NM_000059.3(BRCA2):c.5636A>G (p.Glu1879Gly) rs398122536
NM_000059.3(BRCA2):c.5687C>T (p.Ala1896Val) rs730881539
NM_000059.3(BRCA2):c.5791C>A (p.Gln1931Lys) rs80358807
NM_000059.3(BRCA2):c.6152A>G (p.Asn2051Ser) rs398122549
NM_000059.3(BRCA2):c.6242A>C (p.Glu2081Ala) rs1593907983
NM_000059.3(BRCA2):c.6272G>A (p.Ser2091Asn) rs1060502389
NM_000059.3(BRCA2):c.6322C>A (p.Arg2108Ser) rs55794205
NM_000059.3(BRCA2):c.6399_6401del (p.Asn2135del) rs80359581
NM_000059.3(BRCA2):c.641_643AAG[1] (p.Glu215del) rs80359588
NM_000059.3(BRCA2):c.68-5A>T rs1555280326
NM_000059.3(BRCA2):c.6991A>G (p.Thr2331Ala) rs80358926
NM_000059.3(BRCA2):c.7127C>T (p.Ala2376Val) rs1593917850
NM_000059.3(BRCA2):c.7170T>A (p.Asn2390Lys) rs1555286027
NM_000059.3(BRCA2):c.71_72insTTTTTTT (p.Leu24fs) rs397507903
NM_000059.3(BRCA2):c.7234A>C (p.Thr2412Pro) rs876659118
NM_000059.3(BRCA2):c.7298A>G (p.Gln2433Arg) rs1593918295
NM_000059.3(BRCA2):c.7420_7422GAA[2] (p.Glu2476del) rs876659222
NM_000059.3(BRCA2):c.7499G>A (p.Arg2500Lys) rs80358976
NM_000059.3(BRCA2):c.7930A>G (p.Asn2644Asp) rs431825360
NM_000059.3(BRCA2):c.7977-7C>T rs397507948
NM_000059.3(BRCA2):c.7985C>T (p.Thr2662Met) rs431825362
NM_000059.3(BRCA2):c.8036A>G (p.Asp2679Gly) rs80359041
NM_000059.3(BRCA2):c.8153T>C (p.Ile2718Thr) rs80359060
NM_000059.3(BRCA2):c.8360G>A (p.Arg2787His) rs80359078
NM_000059.3(BRCA2):c.8588_8590dup (p.Glu2863dup) rs730881616
NM_000059.3(BRCA2):c.8668C>A (p.Leu2890Ile) rs80359127
NM_000059.3(BRCA2):c.8869C>A (p.Gln2957Lys) rs276174913
NM_000059.3(BRCA2):c.9011A>G (p.Lys3004Arg) rs587782779
NM_000059.3(BRCA2):c.9043A>G (p.Lys3015Glu) rs587781497
NM_000059.3(BRCA2):c.9265C>T (p.Pro3089Ser) rs1593199583
NM_000059.3(BRCA2):c.94T>C (p.Phe32Leu) rs397508057
NM_000059.3(BRCA2):c.9700A>G (p.Met3234Val) rs730881574
NM_000059.3(BRCA2):c.9770A>G (p.Lys3257Arg) rs55847618
NM_000059.3(BRCA2):c.9820T>G (p.Leu3274Val) rs80359244
NM_000059.3(BRCA2):c.9925G>A (p.Glu3309Lys) rs80359251
NM_000059.3(BRCA2):c.9945del (p.Glu3316fs) rs431825381
NM_000059.4(BRCA2):c.-39-12_-39-10del rs276174798
NM_000059.4(BRCA2):c.1012G>A (p.Ala338Thr) rs80358396
NM_000059.4(BRCA2):c.10131A>C (p.Glu3377Asp) rs1064793835
NM_000059.4(BRCA2):c.103C>T (p.Leu35Phe) rs1446479156
NM_000059.4(BRCA2):c.1181A>C (p.Glu394Ala) rs56016241
NM_000059.4(BRCA2):c.1211A>G (p.Asn404Ser) rs80358414
NM_000059.4(BRCA2):c.1471A>G (p.Thr491Ala) rs1566223650
NM_000059.4(BRCA2):c.1483G>A (p.Ala495Thr) rs80358437
NM_000059.4(BRCA2):c.1504A>C (p.Lys502Gln) rs276174809
NM_000059.4(BRCA2):c.1550A>G (p.Asn517Ser) rs80358439
NM_000059.4(BRCA2):c.1564G>C (p.Gly522Arg) rs80358442
NM_000059.4(BRCA2):c.172G>A (p.Glu58Lys) rs397507603
NM_000059.4(BRCA2):c.1953T>G (p.Asp651Glu) rs771442178
NM_000059.4(BRCA2):c.2233A>G (p.Lys745Glu) rs374691587
NM_000059.4(BRCA2):c.2274T>G (p.Ser758Arg) rs142243359
NM_000059.4(BRCA2):c.2281T>C (p.Tyr761His) rs80358499
NM_000059.4(BRCA2):c.2405A>G (p.Asn802Ser) rs876661089
NM_000059.4(BRCA2):c.241T>A (p.Phe81Ile) rs80358507
NM_000059.4(BRCA2):c.2491G>A (p.Val831Ile) rs397507287
NM_000059.4(BRCA2):c.2560A>G (p.Asn854Asp) rs1413706911
NM_000059.4(BRCA2):c.2576T>C (p.Val859Ala) rs1566226964
NM_000059.4(BRCA2):c.2589T>A (p.Asn863Lys) rs80358521
NM_000059.4(BRCA2):c.280C>T (p.Pro94Ser) rs80358531
NM_000059.4(BRCA2):c.2918C>T (p.Ser973Leu) rs397507296
NM_000059.4(BRCA2):c.2998A>C (p.Ile1000Leu) rs1555282999
NM_000059.4(BRCA2):c.3088T>G (p.Phe1030Val) rs80358554
NM_000059.4(BRCA2):c.3152T>C (p.Leu1051Ser) rs778281493
NM_000059.4(BRCA2):c.3170A>G (p.Lys1057Arg) rs80358562
NM_000059.4(BRCA2):c.322A>C (p.Asn108His) rs80358567
NM_000059.4(BRCA2):c.3509C>T (p.Ala1170Val) rs80358599
NM_000059.4(BRCA2):c.353G>A (p.Arg118His) rs80358603
NM_000059.4(BRCA2):c.3835A>G (p.Asn1279Asp) rs80358626
NM_000059.4(BRCA2):c.383A>G (p.Asp128Gly) rs80358627
NM_000059.4(BRCA2):c.3908G>A (p.Gly1303Asp) rs587782645
NM_000059.4(BRCA2):c.4183G>T (p.Ala1395Ser) rs431825318
NM_000059.4(BRCA2):c.4237A>G (p.Lys1413Glu) rs876661198
NM_000059.4(BRCA2):c.4366G>A (p.Glu1456Lys) rs876659847
NM_000059.4(BRCA2):c.449A>G (p.His150Arg) rs397507722
NM_000059.4(BRCA2):c.4627A>G (p.Lys1543Glu) rs786204239
NM_000059.4(BRCA2):c.467A>G (p.Asp156Gly) rs68071147
NM_000059.4(BRCA2):c.4808A>T (p.Asn1603Ile) rs890665355
NM_000059.4(BRCA2):c.5068_5073dup (p.Lys1690_Lys1691dup) rs80359479
NM_000059.4(BRCA2):c.5096A>G (p.Asp1699Gly) rs80358732
NM_000059.4(BRCA2):c.5120C>T (p.Thr1707Ile) rs786202354
NM_000059.4(BRCA2):c.5228G>A (p.Ser1743Asn) rs587782714
NM_000059.4(BRCA2):c.5270A>G (p.Tyr1757Cys) rs587776466
NM_000059.4(BRCA2):c.5284T>G (p.Tyr1762Asp) rs1192019733
NM_000059.4(BRCA2):c.5467A>G (p.Lys1823Glu) rs276174858
NM_000059.4(BRCA2):c.5612G>A (p.Ser1871Asn) rs80358782
NM_000059.4(BRCA2):c.561G>C (p.Glu187Asp) rs754678843
NM_000059.4(BRCA2):c.562G>A (p.Val188Met) rs1555281063
NM_000059.4(BRCA2):c.565G>T (p.Asp189Tyr) rs1555281067
NM_000059.4(BRCA2):c.5674G>A (p.Gly1892Ser) rs786203948
NM_000059.4(BRCA2):c.5729A>G (p.Asn1910Ser) rs276174863
NM_000059.4(BRCA2):c.5729A>T (p.Asn1910Ile) rs276174863
NM_000059.4(BRCA2):c.5885T>C (p.Ile1962Thr) rs1060502377
NM_000059.4(BRCA2):c.589T>C (p.Ser197Pro) rs730881505
NM_000059.4(BRCA2):c.6024G>C (p.Lys2008Asn) rs56324666
NM_000059.4(BRCA2):c.6029T>G (p.Val2010Gly) rs80358839
NM_000059.4(BRCA2):c.6095C>T (p.Ala2032Val) rs786202701
NM_000059.4(BRCA2):c.6125A>C (p.Gln2042Pro) rs80358852
NM_000059.4(BRCA2):c.6281A>G (p.Tyr2094Cys) rs397507838
NM_000059.4(BRCA2):c.62A>G (p.Lys21Arg) rs397507367
NM_000059.4(BRCA2):c.6386A>G (p.Glu2129Gly) rs1566234469
NM_000059.4(BRCA2):c.643G>A (p.Glu215Lys) rs774539540
NM_000059.4(BRCA2):c.6532C>A (p.His2178Asn) rs80358885
NM_000059.4(BRCA2):c.6554C>T (p.Ala2185Val) rs980859921
NM_000059.4(BRCA2):c.6665A>G (p.Tyr2222Cys) rs397507875
NM_000059.4(BRCA2):c.6988A>G (p.Ile2330Val) rs876661032
NM_000059.4(BRCA2):c.709G>A (p.Asp237Asn) rs398122575
NM_000059.4(BRCA2):c.7481G>A (p.Arg2494Gln) rs80358973
NM_000059.4(BRCA2):c.7504C>T (p.Arg2502Cys) rs55716624
NM_000059.4(BRCA2):c.754G>A (p.Asp252Asn) rs549269828
NM_000059.4(BRCA2):c.7618-10T>G rs864622573
NM_000059.4(BRCA2):c.7622A>G (p.Tyr2541Cys) rs1566242642
NM_000059.4(BRCA2):c.7633G>A (p.Val2545Ile) rs80358990
NM_000059.4(BRCA2):c.7712A>G (p.Glu2571Gly) rs55689095
NM_000059.4(BRCA2):c.7992T>G (p.Ile2664Met) rs80359800
NM_000059.4(BRCA2):c.7994A>G (p.Asp2665Gly) rs28897745
NM_000059.4(BRCA2):c.7A>G (p.Ile3Val) rs770479195
NM_000059.4(BRCA2):c.8035G>T (p.Asp2679Tyr) rs80359040
NM_000059.4(BRCA2):c.8092G>A (p.Ala2698Thr) rs80359052
NM_000059.4(BRCA2):c.811G>A (p.Gly271Arg) rs786204274
NM_000059.4(BRCA2):c.8191C>G (p.Gln2731Glu) rs397507966
NM_000059.4(BRCA2):c.8293T>C (p.Cys2765Arg) rs768247528
NM_000059.4(BRCA2):c.8324T>G (p.Met2775Arg) rs80359073
NM_000059.4(BRCA2):c.8482A>G (p.Ile2828Val) rs80359098
NM_000059.4(BRCA2):c.8518A>G (p.Ile2840Val) rs80359103
NM_000059.4(BRCA2):c.8524C>T (p.Arg2842Cys) rs80359104
NM_000059.4(BRCA2):c.8686C>T (p.Arg2896Cys) rs373203204
NM_000059.4(BRCA2):c.8754+9G>A rs749435255
NM_000059.4(BRCA2):c.8902A>G (p.Thr2968Ala) rs587782021
NM_000059.4(BRCA2):c.9078G>C (p.Gln3026His) rs1359207910
NM_000059.4(BRCA2):c.9086C>T (p.Ala3029Val) rs80359162
NM_000059.4(BRCA2):c.9109C>A (p.Gln3037Lys) rs397508037
NM_000059.4(BRCA2):c.9116C>T (p.Pro3039Leu) rs80359167
NM_000059.4(BRCA2):c.9195T>A (p.Phe3065Leu) rs80359179
NM_000059.4(BRCA2):c.9242T>C (p.Val3081Ala) rs80359189
NM_000059.4(BRCA2):c.9271G>A (p.Val3091Ile) rs80359194
NM_000059.4(BRCA2):c.9304G>A (p.Ala3102Thr) rs747073940
NM_000059.4(BRCA2):c.9337A>G (p.Ile3113Val) rs1566258935
NM_000059.4(BRCA2):c.9442G>T (p.Ala3148Ser) rs949790323
NM_000059.4(BRCA2):c.9501+3A>T rs61757642
NM_000059.4(BRCA2):c.9502-12T>G rs81002803
NM_000059.4(BRCA2):c.9510C>G (p.Asp3170Glu) rs876661072
NM_000059.4(BRCA2):c.9645T>A (p.Leu3215=) rs755111487
NM_000059.4(BRCA2):c.9677A>G (p.Tyr3226Cys) rs80359237
NM_000059.4(BRCA2):c.967G>A (p.Val323Ile) rs1566222487
NM_000059.4(BRCA2):c.9875C>T (p.Pro3292Leu) rs56121817
NM_000059.4(BRCA2):c.9986A>G (p.Asn3329Ser) rs76635144

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