List of variants in gene BRCA2 reported as pathogenic by Cancer Genetics and Genomics Laboratory, British Columbia Cancer Agency

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 17

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.6275_6276del (p.Leu2092fs)	rs11571658	0.00003
NM_000059.4(BRCA2):c.8297del (p.Thr2766fs)	rs80359705	0.00001
NM_000059.4(BRCA2):c.8575del (p.Gln2859fs)	rs80359718	0.00001
NM_000059.4(BRCA2):c.314T>G (p.Leu105Ter)	rs80358561
NM_000059.4(BRCA2):c.3170_3174del (p.Lys1057fs)	rs80359373
NM_000059.4(BRCA2):c.3865_3868del (p.Lys1289fs)	rs80359412
NM_000059.4(BRCA2):c.4409_4413del (p.Ile1470fs)	rs397507718
NM_000059.4(BRCA2):c.4631del (p.Asn1544fs)	rs80359460
NM_000059.4(BRCA2):c.5351dup (p.Asn1784fs)	rs80359507
NM_000059.4(BRCA2):c.5471dup (p.Asn1824fs)	rs80359515
NM_000059.4(BRCA2):c.5682C>G (p.Tyr1894Ter)	rs41293497
NM_000059.4(BRCA2):c.6486_6489del (p.Lys2162fs)	rs80359598
NM_000059.4(BRCA2):c.7913_7917del (p.Ala2637_Phe2638insTer)	rs80359686
NM_000059.4(BRCA2):c.7976G>A (p.Arg2659Lys)	rs80359027
NM_000059.4(BRCA2):c.8680del (p.Gln2894fs)	rs397507410
NM_000059.4(BRCA2):c.8904del (p.Val2969fs)	rs80359730
NM_000059.4(BRCA2):c.9076C>T (p.Gln3026Ter)	rs80359159

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