List of variants in gene BRCA2 reported as uncertain significance by Research Molecular Genetics Laboratory, Women's College Hospital, University of Toronto

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 34

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HGVS	dbSNP	gnomAD frequency
NM_000059.4(BRCA2):c.68-7T>A	rs81002830	0.00277
NM_000059.4(BRCA2):c.7435+6G>A	rs81002852	0.00053
NM_000059.4(BRCA2):c.467A>G (p.Asp156Gly)	rs68071147	0.00022
NM_000059.4(BRCA2):c.9271G>A (p.Val3091Ile)	rs80359194	0.00003
NM_000059.4(BRCA2):c.5051C>G (p.Thr1684Ser)	rs80358729	0.00002
NM_000059.4(BRCA2):c.4850G>A (p.Ser1617Asn)	rs397507341	0.00001
NM_000059.4(BRCA2):c.5870T>C (p.Ile1957Thr)	rs587782320	0.00001
NM_000059.4(BRCA2):c.6413T>A (p.Val2138Asp)	rs80358877	0.00001
NM_000059.4(BRCA2):c.6441C>G (p.His2147Gln)	rs80358879	0.00001
NM_000059.4(BRCA2):c.8009C>T (p.Ser2670Leu)	rs80359035	0.00001
NM_000059.4(BRCA2):c.8377G>A (p.Gly2793Arg)	rs80359082	0.00001
NM_000059.4(BRCA2):c.9257-18C>A	rs81002807	0.00001
NM_000059.4(BRCA2):c.9338T>C (p.Ile3113Thr)	rs770003991	0.00001
NM_000059.4(BRCA2):c.1354C>A (p.Leu452Ile)	rs80358424
NM_000059.4(BRCA2):c.2056C>T (p.Leu686Phe)	rs1135401896
NM_000059.4(BRCA2):c.2198T>G (p.Val733Gly)	rs1135401897
NM_000059.4(BRCA2):c.2963A>C (p.Asp988Ala)	rs876659509
NM_000059.4(BRCA2):c.426-12_426-8del	rs276174844
NM_000059.4(BRCA2):c.476-9dup	rs276174849
NM_000059.4(BRCA2):c.5609T>A (p.Phe1870Tyr)	rs1135401908
NM_000059.4(BRCA2):c.5680_5682del (p.Tyr1894del)	rs1135401909
NM_000059.4(BRCA2):c.6361G>A (p.Glu2121Lys)	rs587782183
NM_000059.4(BRCA2):c.7799T>G (p.Phe2600Cys)	rs1135401920
NM_000059.4(BRCA2):c.7805+3A>C	rs81002810
NM_000059.4(BRCA2):c.7806-9T>G	rs397507939
NM_000059.4(BRCA2):c.7868A>G (p.His2623Arg)	rs80359012
NM_000059.4(BRCA2):c.7976+5G>A	rs786201180
NM_000059.4(BRCA2):c.8032A>G (p.Arg2678Gly)	rs80359039
NM_000059.4(BRCA2):c.8229_8243del (p.Arg2744_Gly2748del)	rs80359698
NM_000059.4(BRCA2):c.8332-9T>G	rs1135401926
NM_000059.4(BRCA2):c.8364G>C (p.Trp2788Cys)	rs397507981
NM_000059.4(BRCA2):c.8473G>A (p.Ala2825Thr)	rs587782874
NM_000059.4(BRCA2):c.86T>G (p.Leu29Arg)	rs1135401889
NM_000059.4(BRCA2):c.9491A>T (p.Asn3164Ile)	rs1135401930

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