ClinVar Miner

Variants in gene CARD11

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If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
19 7 200 99 35 23 353

Condition and significance breakdown #

Total conditions: 8
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Immunodeficiency 11; B-cell expansion with NFKB and T-cell anergy 9 0 175 78 26 0 288
not provided 2 3 26 28 4 0 63
not specified 0 0 0 4 4 23 30
B-cell expansion with NFKB and T-cell anergy 4 0 10 0 0 0 14
none provided 0 1 0 3 2 0 6
Immunodeficiency 11 2 3 0 0 0 0 5
Immunodeficiency 11; B-cell expansion with NFKB and T-cell anergy; Immunodeficiency 11b with atopic dermatitis 0 0 4 0 0 0 4
Immunodeficiency 11b with atopic dermatitis 4 0 0 0 0 0 4

Submitter and significance breakdown #

Total submitters: 22
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 9 0 175 94 26 0 304
ITMI 0 0 0 0 0 23 23
Blueprint Genetics 1 0 10 0 0 0 11
OMIM 10 0 0 0 0 0 10
GeneDx 1 1 6 0 0 0 8
Baylor Genetics 0 0 7 0 0 0 7
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 0 1 0 4 2 0 7
CeGaT Praxis fuer Humangenetik Tuebingen 0 2 5 0 0 0 7
Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics,Cincinnati Children's Hospital Medical Center 0 0 0 0 4 0 4
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 0 4 0 4
Genetic Services Laboratory, University of Chicago 0 0 0 3 0 0 3
Lineagen, Inc 0 0 2 0 0 0 2
Rady Children's Institute for Genomic Medicine, Rady Children's Hospital San Diego 0 2 0 0 0 0 2
Institute of Human Genetics, University of Leipzig Medical Center 0 0 2 0 0 0 2
Department of Pathology and Laboratory Medicine,Sinai Health System 0 0 2 0 0 0 2
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 2 0 0 0 2
Mendelics 0 1 0 0 0 0 1
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics 0 0 1 0 0 0 1
Mayo Clinic Laboratories, Mayo Clinic 0 0 1 0 0 0 1
Fulgent Genetics,Fulgent Genetics 0 0 1 0 0 0 1
Quest Diagnostics Nichols Institute San Juan Capistrano 0 0 1 0 0 0 1
UOSD Laboratory of Genetics & Genomics of Rare Diseases,Istituto Giannina Gaslini 0 0 1 0 0 0 1

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