ClinVar Miner

Variants in gene combination CDK4, TSPAN31

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
0 0 130 70 18 2 198

Condition and significance breakdown #

Total conditions: 7
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Condition uncertain significance likely benign benign not provided total
Hereditary melanoma 90 55 1 0 146
Hereditary cancer-predisposing syndrome 45 31 2 0 78
not provided 18 9 7 0 32
Cutaneous malignant melanoma 3 19 1 11 0 30
not specified 8 13 3 2 23
Cutaneous Malignant Melanoma, Dominant 4 0 0 0 4
Ewing sarcoma 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 16
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Submitter uncertain significance likely benign benign not provided total
Invitae 90 55 1 0 146
Ambry Genetics 44 31 2 0 77
GeneDx 11 13 2 0 26
Illumina Clinical Services Laboratory,Illumina 16 0 10 0 26
Quest Diagnostics Nichols Institute San Juan Capistrano 7 4 6 0 16
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 7 5 2 0 14
Mendelics 5 1 0 0 6
Counsyl 3 0 1 0 4
PreventionGenetics,PreventionGenetics 2 0 1 0 3
GeneKor MSA 3 0 0 0 3
ITMI 0 0 0 2 2
True Health Diagnostics 1 1 0 0 2
Fulgent Genetics,Fulgent Genetics 1 0 0 0 1
CeGaT Praxis fuer Humangenetik Tuebingen 1 0 0 0 1
Department of Pathology and Laboratory Medicine,Sinai Health System 1 0 0 0 1
St. Jude Clinical Genomics Lab, St. Jude Children's Research Hospital 1 0 0 0 1

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