ClinVar Miner

List of variants in gene CDK4 reported as uncertain significance

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 209
Download table as spreadsheet
HGVS dbSNP
NC_000012.11:g.(?_58144429)_(58145510_?)dup
NC_000012.11:g.(?_58144433)_(58145506_?)dup
NC_000012.12:g.(?_57748525)_(57751717_?)dup
NC_000012.12:g.(?_57750646)_(57751717_?)dup
NC_000012.12:g.57752350C>T rs1280668662
NM_000075.3(CDK4):c.-171G>A rs886049719
NM_000075.4(CDK4):c.-100G>T rs886049718
NM_000075.4(CDK4):c.-123T>G rs759319348
NM_000075.4(CDK4):c.-2G>A rs771607042
NM_000075.4(CDK4):c.-54C>T rs886049716
NM_000075.4(CDK4):c.-55A>T rs886049717
NM_000075.4(CDK4):c.-74C>T
NM_000075.4(CDK4):c.107G>C (p.Ser36Thr)
NM_000075.4(CDK4):c.109G>A (p.Val37Met) rs1060501930
NM_000075.4(CDK4):c.116T>C (p.Val39Ala)
NM_000075.4(CDK4):c.119C>T (p.Pro40Leu)
NM_000075.4(CDK4):c.11C>A (p.Ser4Tyr)
NM_000075.4(CDK4):c.122A>G (p.Asn41Ser) rs144890720
NM_000075.4(CDK4):c.126AGG[2] (p.Gly48del) rs770784286
NM_000075.4(CDK4):c.127G>C (p.Gly43Arg) rs1595111088
NM_000075.4(CDK4):c.128G>A (p.Gly43Glu)
NM_000075.4(CDK4):c.132_143del (p.Gly45_Gly48del) rs749094206
NM_000075.4(CDK4):c.132_143dup (p.Gly45_Gly48dup)
NM_000075.4(CDK4):c.133G>A (p.Gly45Ser) rs876660318
NM_000075.4(CDK4):c.133G>C (p.Gly45Arg) rs876660318
NM_000075.4(CDK4):c.133G>T (p.Gly45Cys) rs876660318
NM_000075.4(CDK4):c.135_143del (p.Gly46_Gly48del) rs1595111045
NM_000075.4(CDK4):c.137G>A (p.Gly46Glu) rs878853622
NM_000075.4(CDK4):c.138AGG[1] (p.Gly48del) rs1555201374
NM_000075.4(CDK4):c.13C>G (p.Arg5Gly) rs1595111256
NM_000075.4(CDK4):c.142G>A (p.Gly48Ser) rs1595111053
NM_000075.4(CDK4):c.14G>A (p.Arg5Gln) rs1031329993
NM_000075.4(CDK4):c.155G>A (p.Ser52Asn) rs760719270
NM_000075.4(CDK4):c.155G>T (p.Ser52Ile) rs760719270
NM_000075.4(CDK4):c.156C>G (p.Ser52Arg)
NM_000075.4(CDK4):c.160G>A (p.Val54Ile) rs775085950
NM_000075.4(CDK4):c.163C>G (p.Arg55Gly) rs1555201372
NM_000075.4(CDK4):c.163C>T (p.Arg55Cys) rs1555201372
NM_000075.4(CDK4):c.169G>T (p.Val57Leu) rs1555201369
NM_000075.4(CDK4):c.172G>A (p.Ala58Thr)
NM_000075.4(CDK4):c.184C>T (p.Arg62Ter) rs745481376
NM_000075.4(CDK4):c.185G>A (p.Arg62Gln) rs1595110979
NM_000075.4(CDK4):c.193G>A (p.Ala65Thr) rs1595110976
NM_000075.4(CDK4):c.198del (p.Phe66fs) rs1595110961
NM_000075.4(CDK4):c.19G>A (p.Glu7Lys) rs1000052939
NM_000075.4(CDK4):c.200A>T (p.Glu67Val)
NM_000075.4(CDK4):c.209A>G (p.Asn70Ser) rs1595110952
NM_000075.4(CDK4):c.211G>A (p.Val71Ile) rs1555201364
NM_000075.4(CDK4):c.217C>T (p.Arg73Trp) rs1437365423
NM_000075.4(CDK4):c.218+3G>A
NM_000075.4(CDK4):c.218+6_218+7delinsGT
NM_000075.4(CDK4):c.218G>A (p.Arg73Gln)
NM_000075.4(CDK4):c.219-10C>T rs759302811
NM_000075.4(CDK4):c.219-5G>C rs1286893141
NM_000075.4(CDK4):c.219-7T>C rs543798269
NM_000075.4(CDK4):c.222_223delinsCT (p.Met75Leu)
NM_000075.4(CDK4):c.223A>C (p.Met75Leu) rs1343218987
NM_000075.4(CDK4):c.223A>G (p.Met75Val)
NM_000075.4(CDK4):c.224T>G (p.Met75Arg) rs748983604
NM_000075.4(CDK4):c.225G>A (p.Met75Ile) rs1595110823
NM_000075.4(CDK4):c.229G>A (p.Val77Ile) rs730881670
NM_000075.4(CDK4):c.233G>C (p.Cys78Ser) rs1595110816
NM_000075.4(CDK4):c.235G>A (p.Ala79Thr) rs1555201333
NM_000075.4(CDK4):c.235G>C (p.Ala79Pro)
NM_000075.4(CDK4):c.244C>G (p.Arg82Gly)
NM_000075.4(CDK4):c.245G>A (p.Arg82Gln) rs3211612
NM_000075.4(CDK4):c.245G>C (p.Arg82Pro)
NM_000075.4(CDK4):c.248C>A (p.Thr83Asn) rs1595110800
NM_000075.4(CDK4):c.253C>G (p.Arg85Gly) rs759017803
NM_000075.4(CDK4):c.254G>A (p.Arg85Gln) rs587778184
NM_000075.4(CDK4):c.255G>T (p.Arg85=) rs1565806692
NM_000075.4(CDK4):c.260T>G (p.Ile87Ser) rs1555201326
NM_000075.4(CDK4):c.263A>G (p.Lys88Arg) rs1463751654
NM_000075.4(CDK4):c.265G>A (p.Val89Ile) rs1190779336
NM_000075.4(CDK4):c.267A>G (p.Val89=) rs886049715
NM_000075.4(CDK4):c.269C>T (p.Thr90Ile)
NM_000075.4(CDK4):c.279T>G (p.Phe93Leu) rs1478574297
NM_000075.4(CDK4):c.287T>C (p.Val96Ala)
NM_000075.4(CDK4):c.289G>A (p.Asp97Asn) rs1060501932
NM_000075.4(CDK4):c.289G>C (p.Asp97His) rs1060501932
NM_000075.4(CDK4):c.28G>A (p.Ala10Thr)
NM_000075.4(CDK4):c.291C>A (p.Asp97Glu)
NM_000075.4(CDK4):c.295G>A (p.Asp99Asn)
NM_000075.4(CDK4):c.306_322del (p.Tyr103fs)
NM_000075.4(CDK4):c.307T>A (p.Tyr103Asn) rs752767372
NM_000075.4(CDK4):c.307dup (p.Tyr103fs)
NM_000075.4(CDK4):c.310C>A (p.Leu104Met) rs759535768
NM_000075.4(CDK4):c.315C>A (p.Asp105Glu) rs1158206003
NM_000075.4(CDK4):c.315C>G (p.Asp105Glu)
NM_000075.4(CDK4):c.316A>C (p.Lys106Gln) rs1595110711
NM_000075.4(CDK4):c.317A>G (p.Lys106Arg)
NM_000075.4(CDK4):c.319G>A (p.Ala107Thr)
NM_000075.4(CDK4):c.320C>T (p.Ala107Val)
NM_000075.4(CDK4):c.323C>A (p.Pro108His) rs1595110706
NM_000075.4(CDK4):c.326C>T (p.Pro109Leu) rs1595110701
NM_000075.4(CDK4):c.331G>A (p.Gly111Ser) rs1277385976
NM_000075.4(CDK4):c.333C>T (p.Gly111=)
NM_000075.4(CDK4):c.336G>T (p.Leu112Phe) rs1595110684
NM_000075.4(CDK4):c.338C>A (p.Pro113Gln)
NM_000075.4(CDK4):c.340G>C (p.Ala114Pro)
NM_000075.4(CDK4):c.343G>A (p.Glu115Lys) rs772938517
NM_000075.4(CDK4):c.343G>C (p.Glu115Gln) rs772938517
NM_000075.4(CDK4):c.344A>C (p.Glu115Ala)
NM_000075.4(CDK4):c.345A>C (p.Glu115Asp)
NM_000075.4(CDK4):c.346A>G (p.Thr116Ala)
NM_000075.4(CDK4):c.347C>T (p.Thr116Met) rs1060501931
NM_000075.4(CDK4):c.349A>G (p.Ile117Val) rs776343973
NM_000075.4(CDK4):c.352A>C (p.Lys118Gln) rs772689692
NM_000075.4(CDK4):c.353A>G (p.Lys118Arg) rs1555201314
NM_000075.4(CDK4):c.354+3G>C rs746395249
NM_000075.4(CDK4):c.354+6T>A
NM_000075.4(CDK4):c.355-3T>C
NM_000075.4(CDK4):c.355-4C>G rs1406247863
NM_000075.4(CDK4):c.356A>C (p.Asp119Ala)
NM_000075.4(CDK4):c.359T>A (p.Leu120Gln)
NM_000075.4(CDK4):c.364C>G (p.Arg122Gly) rs587778185
NM_000075.4(CDK4):c.364C>T (p.Arg122Cys) rs587778185
NM_000075.4(CDK4):c.365G>A (p.Arg122His) rs34386532
NM_000075.4(CDK4):c.367C>T (p.Gln123Ter) rs1565806579
NM_000075.4(CDK4):c.369G>T (p.Gln123His)
NM_000075.4(CDK4):c.370T>C (p.Phe124Leu)
NM_000075.4(CDK4):c.376A>G (p.Arg126Gly) rs1565806573
NM_000075.4(CDK4):c.385G>A (p.Asp129Asn) rs876660606
NM_000075.4(CDK4):c.38G>A (p.Gly13Asp)
NM_000075.4(CDK4):c.392T>G (p.Leu131Arg)
NM_000075.4(CDK4):c.397G>A (p.Ala133Thr) rs751684879
NM_000075.4(CDK4):c.401A>G (p.Asn134Ser) rs1595110530
NM_000075.4(CDK4):c.404G>A (p.Cys135Tyr) rs1340574386
NM_000075.4(CDK4):c.409G>A (p.Val137Ile) rs150281463
NM_000075.4(CDK4):c.409G>C (p.Val137Leu) rs150281463
NM_000075.4(CDK4):c.414C>G (p.His138Gln)
NM_000075.4(CDK4):c.415C>G (p.Arg139Gly) rs753579957
NM_000075.4(CDK4):c.416G>A (p.Arg139Gln) rs763652580
NM_000075.4(CDK4):c.418G>C (p.Asp140His) rs1555201308
NM_000075.4(CDK4):c.418G>T (p.Asp140Tyr) rs1555201308
NM_000075.4(CDK4):c.421C>G (p.Leu141Val) rs1246306482
NM_000075.4(CDK4):c.42C>T (p.Val14=) rs786203182
NM_000075.4(CDK4):c.431A>G (p.Glu144Gly) rs863224603
NM_000075.4(CDK4):c.43G>A (p.Gly15Ser) rs1355460580
NM_000075.4(CDK4):c.43G>C (p.Gly15Arg)
NM_000075.4(CDK4):c.442G>C (p.Val148Leu) rs1595110489
NM_000075.4(CDK4):c.442G>T (p.Val148Leu) rs1595110489
NM_000075.4(CDK4):c.451G>A (p.Gly151Ser) rs1280774592
NM_000075.4(CDK4):c.452G>A (p.Gly151Asp) rs1595110472
NM_000075.4(CDK4):c.458C>G (p.Thr153Arg)
NM_000075.4(CDK4):c.458C>T (p.Thr153Ile) rs1443076952
NM_000075.4(CDK4):c.460G>C (p.Val154Leu) rs563692823
NM_000075.4(CDK4):c.461T>C (p.Val154Ala) rs1555201304
NM_000075.4(CDK4):c.477del (p.Phe159fs) rs786203016
NM_000075.4(CDK4):c.484G>C (p.Ala162Pro) rs1555201301
NM_000075.4(CDK4):c.484G>T (p.Ala162Ser) rs1555201301
NM_000075.4(CDK4):c.485C>A (p.Ala162Asp) rs1565806506
NM_000075.4(CDK4):c.487_488delinsGC (p.Arg163Ala)
NM_000075.4(CDK4):c.489A>T (p.Arg163Ser) rs876658462
NM_000075.4(CDK4):c.48C>G (p.Ala16=) rs1311074831
NM_000075.4(CDK4):c.491T>C (p.Ile164Thr) rs1222529576
NM_000075.4(CDK4):c.494A>G (p.Tyr165Cys)
NM_000075.4(CDK4):c.497G>C (p.Ser166Thr) rs876660536
NM_000075.4(CDK4):c.49T>C (p.Tyr17His) rs1555201383
NM_000075.4(CDK4):c.4G>A (p.Ala2Thr) rs1483991096
NM_000075.4(CDK4):c.502C>T (p.Gln168Ter) rs1555201299
NM_000075.4(CDK4):c.504G>C (p.Gln168His) rs770086242
NM_000075.4(CDK4):c.505_522+5del rs1555201295
NM_000075.4(CDK4):c.517C>A (p.Pro173Thr) rs768904034
NM_000075.4(CDK4):c.520G>A (p.Val174Met) rs780052789
NM_000075.4(CDK4):c.522+1G>A rs1281910320
NM_000075.4(CDK4):c.522+4A>G rs1595110395
NM_000075.4(CDK4):c.523-4T>A rs587780667
NM_000075.4(CDK4):c.523G>A (p.Val175Ile) rs587778186
NM_000075.4(CDK4):c.529A>G (p.Thr177Ala) rs1555201280
NM_000075.4(CDK4):c.532C>T (p.Leu178Phe) rs1030964946
NM_000075.4(CDK4):c.541C>G (p.Arg181Gly) rs1595110257
NM_000075.4(CDK4):c.542G>A (p.Arg181Gln) rs772079285
NM_000075.4(CDK4):c.549_567del (p.Glu184fs)
NM_000075.4(CDK4):c.550G>A (p.Glu184Lys) rs1595110227
NM_000075.4(CDK4):c.553G>A (p.Val185Ile)
NM_000075.4(CDK4):c.55A>G (p.Thr19Ala)
NM_000075.4(CDK4):c.560T>G (p.Leu187Arg)
NM_000075.4(CDK4):c.562C>A (p.Gln188Lys) rs1555201274
NM_000075.4(CDK4):c.571T>A (p.Tyr191Asn)
NM_000075.4(CDK4):c.571T>C (p.Tyr191His)
NM_000075.4(CDK4):c.572A>G (p.Tyr191Cys)
NM_000075.4(CDK4):c.578C>T (p.Thr193Ile)
NM_000075.4(CDK4):c.580C>T (p.Pro194Ser) rs1264069202
NM_000075.4(CDK4):c.581C>A (p.Pro194His)
NM_000075.4(CDK4):c.581C>T (p.Pro194Leu) rs1198423952
NM_000075.4(CDK4):c.583G>A (p.Val195Met)
NM_000075.4(CDK4):c.590T>C (p.Met197Thr)
NM_000075.4(CDK4):c.599T>C (p.Val200Ala) rs1060501929
NM_000075.4(CDK4):c.605G>C (p.Cys202Ser) rs1424791303
NM_000075.4(CDK4):c.610T>A (p.Phe204Ile)
NM_000075.4(CDK4):c.613G>A (p.Ala205Thr) rs368013594
NM_000075.4(CDK4):c.620T>A (p.Met207Lys)
NM_000075.4(CDK4):c.620T>C (p.Met207Thr)
NM_000075.4(CDK4):c.625C>T (p.Arg209Cys) rs140644696
NM_000075.4(CDK4):c.626G>A (p.Arg209His) rs754423955
NM_000075.4(CDK4):c.628C>T (p.Arg210Ter) rs1595110146
NM_000075.4(CDK4):c.629G>A (p.Arg210Gln) rs373619077
NM_000075.4(CDK4):c.629G>C (p.Arg210Pro) rs373619077
NM_000075.4(CDK4):c.629G>T (p.Arg210Leu)
NM_000075.4(CDK4):c.632+4T>A rs1397979744
NM_000075.4(CDK4):c.632+5dup rs1555201260
NM_000075.4(CDK4):c.632+6G>A
NM_000075.4(CDK4):c.632+9C>T rs1192976748
NM_000075.4(CDK4):c.632A>C (p.Lys211Thr) rs765656720
NM_000075.4(CDK4):c.632A>T (p.Lys211Met) rs765656720
NM_000075.4(CDK4):c.64A>C (p.Lys22Gln) rs1555201381
NM_000075.4(CDK4):c.88C>T (p.His30Tyr) rs750707985
NM_000075.4(CDK4):c.93T>G (p.Phe31Leu) rs1595111145

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.