ClinVar Miner

Variants in gene combination COMT, TXNRD2

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response not provided total
0 0 17 5 1 4 1 27

Condition and significance breakdown #

Total conditions: 6
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Condition uncertain significance likely benign benign drug response not provided total
Primary dilated cardiomyopathy 12 3 0 0 0 15
Cardiovascular phenotype 8 3 0 0 0 11
Tramadol response 0 0 0 4 0 4
not provided 2 0 1 0 1 4
Glucocorticoid deficiency 5 1 0 0 0 0 1
Primary familial hypertrophic cardiomyopathy 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 8
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Submitter uncertain significance likely benign benign drug response not provided total
Invitae 12 3 0 0 0 15
Ambry Genetics 8 3 0 0 0 11
Bruce Budowle Laboratory, University of North Texas Health Science Center 0 0 0 4 0 4
GeneDx 1 0 1 0 0 2
Bionano Laboratories 1 0 0 0 0 1
Fulgent Genetics, Fulgent Genetics 1 0 0 0 0 1
Blueprint Genetics 1 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 1 1

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