NM_000769.1(CYP2C19):c.991A>G (p.Ile331Val)
|
rs3758581
|
0.95228
|
NM_000769.4(CYP2C19):c.99C>T (p.Pro33=)
|
rs17885098
|
0.92070
|
NC_000010.11:g.94645745G>A
|
rs12777823
|
0.18950
|
CYP2C19*35
|
rs12769205
|
0.17352
|
CYP2C19*35/*35
|
rs12769205
|
0.17352
|
NM_000769.4(CYP2C19):c.681G>A (p.Pro227=)
|
rs4244285
|
0.16806
|
NM_000769.4(CYP2C19):c.1251A>C (p.Gly417=)
|
rs17886522
|
0.00837
|
CYP2C19*15
|
rs17882687
|
0.00588
|
CYP2C19*15/*15
|
rs17882687
|
0.00588
|
NM_000769.4(CYP2C19):c.1059C>T (p.His353=)
|
rs17882744
|
0.00513
|
CYP2C19*13
|
rs17879685
|
0.00470
|
CYP2C19*13/*13
|
rs17879685
|
0.00470
|
CYP2C19*9/*9
|
rs17884712
|
0.00364
|
NM_000769.1(CYP2C19):c.431G>A (p.Arg144His)
|
rs17884712
|
0.00364
|
CYP2C19*11
|
rs58973490
|
0.00294
|
CYP2C19*11/*11
|
rs58973490
|
0.00294
|
CYP2C19*8/*8
|
rs41291556
|
0.00159
|
NM_000769.1(CYP2C19):c.358T>C (p.Trp120Arg)
|
rs41291556
|
0.00159
|
CYP2C19*4A/*4A
|
rs28399504
|
0.00156
|
NM_000769.1(CYP2C19):c.1A>G (p.Met1Val)
|
rs28399504
|
0.00156
|
CYP2C19*3/*3
|
rs4986893
|
0.00149
|
NM_000769.1(CYP2C19):c.636G>A (p.Trp212Ter)
|
rs4986893
|
0.00149
|
CYP2C19*10
|
rs6413438
|
0.00093
|
CYP2C19*10/*10
|
rs6413438
|
0.00093
|
CYP2C19*30
|
rs145328984
|
0.00090
|
CYP2C19*30/*30
|
rs145328984
|
0.00090
|
CYP2C19*12
|
rs55640102
|
0.00036
|
CYP2C19*12/*12
|
rs55640102
|
0.00036
|
CYP2C19*6/*6
|
rs72552267
|
0.00034
|
NM_000769.1(CYP2C19):c.395G>A (p.Arg132Gln)
|
rs72552267
|
0.00034
|
CYP2C19*16
|
rs192154563
|
0.00010
|
CYP2C19*16/*16
|
rs192154563
|
0.00010
|
CYP2C19*18
|
rs138142612
|
0.00005
|
CYP2C19*18/*18
|
rs138142612
|
0.00005
|
CYP2C19*33
|
rs370803989
|
0.00005
|
CYP2C19*33/*33
|
rs370803989
|
0.00005
|
NM_000769.4(CYP2C19):c.614T>G (p.Ile205Ser)
|
rs747232605
|
0.00005
|
CYP2C19*23
|
rs118203756
|
0.00003
|
CYP2C19*23/*23
|
rs118203756
|
0.00003
|
NM_000769.4(CYP2C19):c.1252A>G (p.Asn418Asp)
|
rs776970249
|
0.00003
|
CYP2C19*26
|
rs375781227
|
0.00001
|
CYP2C19*26/*26
|
rs375781227
|
0.00001
|
CYP2C19*5/*5
|
rs56337013
|
0.00001
|
NM_000769.1(CYP2C19):c.1297C>T (p.Arg433Trp)
|
rs56337013
|
0.00001
|
NM_000769.4(CYP2C19):c.1067A>C (p.Gln356Pro)
|
rs371241592
|
0.00001
|
NM_000769.4(CYP2C19):c.1085T>C (p.Ile362Thr)
|
rs1342382950
|
0.00001
|
NM_000769.4(CYP2C19):c.1094G>C (p.Ser365Thr)
|
rs1384476546
|
0.00001
|
NM_000769.4(CYP2C19):c.1173C>A (p.Leu391=)
|
rs935030527
|
0.00001
|
NM_000769.4(CYP2C19):c.244G>A (p.Val82Met)
|
rs1175482704
|
0.00001
|
NM_000769.4(CYP2C19):c.392T>C (p.Leu131Pro)
|
rs371309036
|
0.00001
|
CYP2C19*10/*11
|
|
|
CYP2C19*10/*12
|
|
|
CYP2C19*10/*13
|
|
|
CYP2C19*10/*14
|
|
|
CYP2C19*10/*15
|
|
|
CYP2C19*10/*16
|
|
|
CYP2C19*10/*18
|
|
|
CYP2C19*10/*19
|
|
|
CYP2C19*10/*22
|
|
|
CYP2C19*10/*23
|
|
|
CYP2C19*10/*24
|
|
|
CYP2C19*10/*25
|
|
|
CYP2C19*10/*26
|
|
|
CYP2C19*10/*29
|
|
|
CYP2C19*10/*30
|
|
|
CYP2C19*10/*31
|
|
|
CYP2C19*10/*32
|
|
|
CYP2C19*10/*33
|
|
|
CYP2C19*10/*35
|
|
|
CYP2C19*11/*12
|
|
|
CYP2C19*11/*13
|
|
|
CYP2C19*11/*14
|
|
|
CYP2C19*11/*15
|
|
|
CYP2C19*11/*16
|
|
|
CYP2C19*11/*18
|
|
|
CYP2C19*11/*19
|
|
|
CYP2C19*11/*22
|
|
|
CYP2C19*11/*23
|
|
|
CYP2C19*11/*24
|
|
|
CYP2C19*11/*25
|
|
|
CYP2C19*11/*26
|
|
|
CYP2C19*11/*29
|
|
|
CYP2C19*11/*30
|
|
|
CYP2C19*11/*31
|
|
|
CYP2C19*11/*32
|
|
|
CYP2C19*11/*33
|
|
|
CYP2C19*11/*35
|
|
|
CYP2C19*12/*13
|
|
|
CYP2C19*12/*14
|
|
|
CYP2C19*12/*15
|
|
|
CYP2C19*12/*16
|
|
|
CYP2C19*12/*18
|
|
|
CYP2C19*12/*19
|
|
|
CYP2C19*12/*22
|
|
|
CYP2C19*12/*23
|
|
|
CYP2C19*12/*24
|
|
|
CYP2C19*12/*25
|
|
|
CYP2C19*12/*26
|
|
|
CYP2C19*12/*29
|
|
|
CYP2C19*12/*30
|
|
|
CYP2C19*12/*31
|
|
|
CYP2C19*12/*32
|
|
|
CYP2C19*12/*33
|
|
|
CYP2C19*12/*35
|
|
|
CYP2C19*13/*14
|
|
|
CYP2C19*13/*15
|
|
|
CYP2C19*13/*16
|
|
|
CYP2C19*13/*18
|
|
|
CYP2C19*13/*19
|
|
|
CYP2C19*13/*22
|
|
|
CYP2C19*13/*23
|
|
|
CYP2C19*13/*24
|
|
|
CYP2C19*13/*25
|
|
|
CYP2C19*13/*26
|
|
|
CYP2C19*13/*29
|
|
|
CYP2C19*13/*30
|
|
|
CYP2C19*13/*31
|
|
|
CYP2C19*13/*32
|
|
|
CYP2C19*13/*33
|
|
|
CYP2C19*13/*35
|
|
|
CYP2C19*14
|
rs55752064
|
|
CYP2C19*14/*14
|
rs55752064
|
|
CYP2C19*14/*15
|
|
|
CYP2C19*14/*16
|
|
|
CYP2C19*14/*18
|
|
|
CYP2C19*14/*19
|
|
|
CYP2C19*14/*22
|
|
|
CYP2C19*14/*23
|
|
|
CYP2C19*14/*24
|
|
|
CYP2C19*14/*25
|
|
|
CYP2C19*14/*26
|
|
|
CYP2C19*14/*29
|
|
|
CYP2C19*14/*30
|
|
|
CYP2C19*14/*31
|
|
|
CYP2C19*14/*32
|
|
|
CYP2C19*14/*33
|
|
|
CYP2C19*14/*35
|
|
|
CYP2C19*15/*16
|
|
|
CYP2C19*15/*18
|
|
|
CYP2C19*15/*19
|
|
|
CYP2C19*15/*22
|
|
|
CYP2C19*15/*23
|
|
|
CYP2C19*15/*24
|
|
|
CYP2C19*15/*25
|
|
|
CYP2C19*15/*26
|
|
|
CYP2C19*15/*29
|
|
|
CYP2C19*15/*30
|
|
|
CYP2C19*15/*31
|
|
|
CYP2C19*15/*32
|
|
|
CYP2C19*15/*33
|
|
|
CYP2C19*15/*35
|
|
|
CYP2C19*16/*18
|
|
|
CYP2C19*16/*19
|
|
|
CYP2C19*16/*22
|
|
|
CYP2C19*16/*23
|
|
|
CYP2C19*16/*24
|
|
|
CYP2C19*16/*25
|
|
|
CYP2C19*16/*26
|
|
|
CYP2C19*16/*29
|
|
|
CYP2C19*16/*30
|
|
|
CYP2C19*16/*31
|
|
|
CYP2C19*16/*32
|
|
|
CYP2C19*16/*33
|
|
|
CYP2C19*16/*35
|
|
|
CYP2C19*18/*19
|
|
|
CYP2C19*18/*22
|
|
|
CYP2C19*18/*23
|
|
|
CYP2C19*18/*24
|
|
|
CYP2C19*18/*25
|
|
|
CYP2C19*18/*26
|
|
|
CYP2C19*18/*29
|
|
|
CYP2C19*18/*30
|
|
|
CYP2C19*18/*31
|
|
|
CYP2C19*18/*32
|
|
|
CYP2C19*18/*33
|
|
|
CYP2C19*18/*35
|
|
|
CYP2C19*19
|
rs1564657013
|
|
CYP2C19*19/*19
|
rs1564657013
|
|
CYP2C19*19/*22
|
|
|
CYP2C19*19/*23
|
|
|
CYP2C19*19/*24
|
|
|
CYP2C19*19/*25
|
|
|
CYP2C19*19/*26
|
|
|
CYP2C19*19/*29
|
|
|
CYP2C19*19/*30
|
|
|
CYP2C19*19/*31
|
|
|
CYP2C19*19/*32
|
|
|
CYP2C19*19/*33
|
|
|
CYP2C19*19/*35
|
|
|
CYP2C19*2
|
|
|
CYP2C19*2/*10
|
|
|
CYP2C19*2/*11
|
|
|
CYP2C19*2/*12
|
|
|
CYP2C19*2/*13
|
|
|
CYP2C19*2/*14
|
|
|
CYP2C19*2/*15
|
|
|
CYP2C19*2/*16
|
|
|
CYP2C19*2/*18
|
|
|
CYP2C19*2/*19
|
|
|
CYP2C19*2/*2
|
|
|
CYP2C19*2/*22
|
|
|
CYP2C19*2/*23
|
|
|
CYP2C19*2/*24
|
|
|
CYP2C19*2/*25
|
|
|
CYP2C19*2/*26
|
|
|
CYP2C19*2/*29
|
|
|
CYP2C19*2/*3
|
|
|
CYP2C19*2/*30
|
|
|
CYP2C19*2/*31
|
|
|
CYP2C19*2/*32
|
|
|
CYP2C19*2/*33
|
|
|
CYP2C19*2/*35
|
|
|
CYP2C19*2/*4A
|
|
|
CYP2C19*2/*5
|
|
|
CYP2C19*2/*6
|
|
|
CYP2C19*2/*7
|
|
|
CYP2C19*2/*8
|
|
|
CYP2C19*2/*9
|
|
|
CYP2C19*22
|
rs140278421
|
|
CYP2C19*22/*22
|
rs140278421
|
|
CYP2C19*22/*23
|
|
|
CYP2C19*22/*24
|
|
|
CYP2C19*22/*25
|
|
|
CYP2C19*22/*26
|
|
|
CYP2C19*22/*29
|
|
|
CYP2C19*22/*30
|
|
|
CYP2C19*22/*31
|
|
|
CYP2C19*22/*32
|
|
|
CYP2C19*22/*33
|
|
|
CYP2C19*22/*35
|
|
|
CYP2C19*23/*24
|
|
|
CYP2C19*23/*25
|
|
|
CYP2C19*23/*26
|
|
|
CYP2C19*23/*29
|
|
|
CYP2C19*23/*30
|
|
|
CYP2C19*23/*31
|
|
|
CYP2C19*23/*32
|
|
|
CYP2C19*23/*33
|
|
|
CYP2C19*23/*35
|
|
|
CYP2C19*24
|
|
|
CYP2C19*24/*24
|
|
|
CYP2C19*24/*25
|
|
|
CYP2C19*24/*26
|
|
|
CYP2C19*24/*29
|
|
|
CYP2C19*24/*30
|
|
|
CYP2C19*24/*31
|
|
|
CYP2C19*24/*32
|
|
|
CYP2C19*24/*33
|
|
|
CYP2C19*24/*35
|
|
|
CYP2C19*25
|
rs118203759
|
|
CYP2C19*25/*25
|
rs118203759
|
|
CYP2C19*25/*26
|
|
|
CYP2C19*25/*29
|
|
|
CYP2C19*25/*30
|
|
|
CYP2C19*25/*31
|
|
|
CYP2C19*25/*32
|
|
|
CYP2C19*25/*33
|
|
|
CYP2C19*25/*35
|
|
|
CYP2C19*26/*29
|
|
|
CYP2C19*26/*30
|
|
|
CYP2C19*26/*31
|
|
|
CYP2C19*26/*32
|
|
|
CYP2C19*26/*33
|
|
|
CYP2C19*26/*35
|
|
|
CYP2C19*29
|
rs1564656981
|
|
CYP2C19*29/*29
|
rs1564656981
|
|
CYP2C19*29/*30
|
|
|
CYP2C19*29/*31
|
|
|
CYP2C19*29/*32
|
|
|
CYP2C19*29/*33
|
|
|
CYP2C19*29/*35
|
|
|
CYP2C19*3/*10
|
|
|
CYP2C19*3/*11
|
|
|
CYP2C19*3/*12
|
|
|
CYP2C19*3/*13
|
|
|
CYP2C19*3/*14
|
|
|
CYP2C19*3/*15
|
|
|
CYP2C19*3/*16
|
|
|
CYP2C19*3/*18
|
|
|
CYP2C19*3/*19
|
|
|
CYP2C19*3/*22
|
|
|
CYP2C19*3/*23
|
|
|
CYP2C19*3/*24
|
|
|
CYP2C19*3/*25
|
|
|
CYP2C19*3/*26
|
|
|
CYP2C19*3/*29
|
|
|
CYP2C19*3/*30
|
|
|
CYP2C19*3/*31
|
|
|
CYP2C19*3/*32
|
|
|
CYP2C19*3/*33
|
|
|
CYP2C19*3/*35
|
|
|
CYP2C19*3/*4A
|
|
|
CYP2C19*3/*5
|
|
|
CYP2C19*3/*6
|
|
|
CYP2C19*3/*7
|
|
|
CYP2C19*3/*8
|
|
|
CYP2C19*3/*9
|
|
|
CYP2C19*30/*31
|
|
|
CYP2C19*30/*32
|
|
|
CYP2C19*30/*33
|
|
|
CYP2C19*30/*35
|
|
|
CYP2C19*31
|
rs1564660997
|
|
CYP2C19*31/*31
|
rs1564660997
|
|
CYP2C19*31/*32
|
|
|
CYP2C19*31/*33
|
|
|
CYP2C19*31/*35
|
|
|
CYP2C19*32
|
rs1288601658
|
|
CYP2C19*32/*32
|
rs1288601658
|
|
CYP2C19*32/*33
|
|
|
CYP2C19*32/*35
|
|
|
CYP2C19*33/*35
|
|
|
CYP2C19*4A/*10
|
|
|
CYP2C19*4A/*11
|
|
|
CYP2C19*4A/*12
|
|
|
CYP2C19*4A/*13
|
|
|
CYP2C19*4A/*14
|
|
|
CYP2C19*4A/*15
|
|
|
CYP2C19*4A/*16
|
|
|
CYP2C19*4A/*18
|
|
|
CYP2C19*4A/*19
|
|
|
CYP2C19*4A/*22
|
|
|
CYP2C19*4A/*23
|
|
|
CYP2C19*4A/*24
|
|
|
CYP2C19*4A/*25
|
|
|
CYP2C19*4A/*26
|
|
|
CYP2C19*4A/*29
|
|
|
CYP2C19*4A/*30
|
|
|
CYP2C19*4A/*31
|
|
|
CYP2C19*4A/*32
|
|
|
CYP2C19*4A/*33
|
|
|
CYP2C19*4A/*35
|
|
|
CYP2C19*4A/*5
|
|
|
CYP2C19*4A/*6
|
|
|
CYP2C19*4A/*7
|
|
|
CYP2C19*4A/*8
|
|
|
CYP2C19*4A/*9
|
|
|
CYP2C19*5/*10
|
|
|
CYP2C19*5/*11
|
|
|
CYP2C19*5/*12
|
|
|
CYP2C19*5/*13
|
|
|
CYP2C19*5/*14
|
|
|
CYP2C19*5/*15
|
|
|
CYP2C19*5/*16
|
|
|
CYP2C19*5/*18
|
|
|
CYP2C19*5/*19
|
|
|
CYP2C19*5/*22
|
|
|
CYP2C19*5/*23
|
|
|
CYP2C19*5/*24
|
|
|
CYP2C19*5/*25
|
|
|
CYP2C19*5/*26
|
|
|
CYP2C19*5/*29
|
|
|
CYP2C19*5/*30
|
|
|
CYP2C19*5/*31
|
|
|
CYP2C19*5/*32
|
|
|
CYP2C19*5/*33
|
|
|
CYP2C19*5/*35
|
|
|
CYP2C19*5/*6
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CYP2C19*5/*7
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CYP2C19*5/*8
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CYP2C19*5/*9
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CYP2C19*6/*10
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CYP2C19*6/*11
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CYP2C19*6/*12
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CYP2C19*6/*13
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CYP2C19*6/*14
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CYP2C19*6/*15
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CYP2C19*6/*16
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CYP2C19*6/*18
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CYP2C19*6/*19
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CYP2C19*6/*22
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CYP2C19*6/*23
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CYP2C19*6/*24
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CYP2C19*6/*25
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CYP2C19*6/*26
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CYP2C19*6/*29
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CYP2C19*6/*30
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CYP2C19*6/*31
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CYP2C19*6/*32
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CYP2C19*6/*33
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CYP2C19*6/*35
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CYP2C19*6/*7
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CYP2C19*6/*8
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CYP2C19*6/*9
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CYP2C19*7/*10
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CYP2C19*7/*11
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CYP2C19*7/*12
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CYP2C19*7/*13
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CYP2C19*7/*14
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CYP2C19*7/*15
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CYP2C19*7/*16
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CYP2C19*7/*18
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CYP2C19*7/*19
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CYP2C19*7/*22
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CYP2C19*7/*23
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CYP2C19*7/*24
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CYP2C19*7/*25
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CYP2C19*7/*26
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CYP2C19*7/*29
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CYP2C19*7/*30
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CYP2C19*7/*31
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CYP2C19*7/*32
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CYP2C19*7/*33
|
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CYP2C19*7/*35
|
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CYP2C19*7/*7
|
rs72558186
|
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CYP2C19*7/*8
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CYP2C19*7/*9
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CYP2C19*8/*10
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CYP2C19*8/*11
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CYP2C19*8/*12
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CYP2C19*8/*13
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CYP2C19*8/*14
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CYP2C19*8/*15
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CYP2C19*8/*16
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CYP2C19*8/*18
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CYP2C19*8/*19
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CYP2C19*8/*22
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CYP2C19*8/*23
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CYP2C19*8/*24
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CYP2C19*8/*25
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CYP2C19*8/*26
|
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CYP2C19*8/*29
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CYP2C19*8/*30
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CYP2C19*8/*31
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CYP2C19*8/*32
|
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CYP2C19*8/*33
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CYP2C19*8/*35
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CYP2C19*8/*9
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CYP2C19*9/*10
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CYP2C19*9/*11
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CYP2C19*9/*12
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CYP2C19*9/*13
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CYP2C19*9/*14
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CYP2C19*9/*15
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CYP2C19*9/*16
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CYP2C19*9/*18
|
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CYP2C19*9/*19
|
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CYP2C19*9/*22
|
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CYP2C19*9/*23
|
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CYP2C19*9/*24
|
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CYP2C19*9/*25
|
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CYP2C19*9/*26
|
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CYP2C19*9/*29
|
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CYP2C19*9/*30
|
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CYP2C19*9/*31
|
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CYP2C19*9/*32
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CYP2C19*9/*33
|
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CYP2C19*9/*35
|
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|
GRCh37/hg19 10q23.33(chr10:96497260-96558710)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96497751-96560546)
|
|
|
GRCh37/hg19 10q23.33(chr10:96501534-96548712)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96502305-96562508)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96533912-96598380)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96534277-96599102)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96558287-96606761)x1
|
|
|
GRCh37/hg19 10q23.33(chr10:96562918-96606761)x1
|
|
|
NM_000769.1(CYP2C19):c.819+2T>A
|
rs72558186
|
|
NM_000769.4(CYP2C19):c.1188T>A (p.His396Gln)
|
rs2492894300
|
|
NM_000769.4(CYP2C19):c.1240G>C (p.Asp414His)
|
rs1849628801
|
|
NM_000769.4(CYP2C19):c.1386T>G (p.Ile462Met)
|
|
|
NM_000769.4(CYP2C19):c.1393A>G (p.Lys465Glu)
|
|
|
NM_000769.4(CYP2C19):c.1406C>A (p.Thr469Lys)
|
|
|
NM_000769.4(CYP2C19):c.1409C>T (p.Thr470Ile)
|
rs2492899082
|
|
NM_000769.4(CYP2C19):c.146A>T (p.Asp49Val)
|
|
|
NM_000769.4(CYP2C19):c.182A>G (p.Tyr61Cys)
|
|
|
NM_000769.4(CYP2C19):c.260T>A (p.Leu87Gln)
|
rs758114852
|
|
NM_000769.4(CYP2C19):c.335T>C (p.Ile112Thr)
|
|
|
NM_000769.4(CYP2C19):c.37T>A (p.Cys13Ser)
|
|
|
NM_000769.4(CYP2C19):c.404G>T (p.Gly135Val)
|
|
|
NM_000769.4(CYP2C19):c.430C>A (p.Arg144Ser)
|
rs368767518
|
|
NM_000769.4(CYP2C19):c.491G>T (p.Cys164Phe)
|
|
|
NM_000769.4(CYP2C19):c.595G>A (p.Glu199Lys)
|
rs2492771434
|
|
NM_000769.4(CYP2C19):c.644T>C (p.Ile215Thr)
|
rs2492773565
|
|
NM_000769.4(CYP2C19):c.664A>G (p.Ile222Val)
|
rs1437628059
|
|
NM_000769.4(CYP2C19):c.681G>T (p.Pro227=)
|
rs4244285
|
|
NM_000769.4(CYP2C19):c.69C>G (p.Ser23Arg)
|
|
|
NM_000769.4(CYP2C19):c.910A>C (p.Thr304Pro)
|
rs2492837992
|
|
NM_000769.4(CYP2C19):c.955G>A (p.Val319Ile)
|
|
|
NM_000769.4(CYP2C19):c.959C>T (p.Thr320Ile)
|
|
|