ClinVar Miner

Variants in gene FANCC

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
24 32 115 88 16 10 243

Condition and significance breakdown #

Total conditions: 6
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Fanconi anemia 18 2 72 20 5 0 114
not specified 0 0 7 66 14 8 87
not provided 9 6 52 11 3 2 78
Fanconi anemia, complementation group C 9 25 14 2 0 0 47
Hereditary cancer-predisposing syndrome 3 0 12 10 3 0 27
Carcinoma of colon 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 25
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
GeneDx 9 6 49 70 14 0 148
Invitae 18 2 66 17 5 0 108
Ambry Genetics 3 0 12 10 2 0 27
Counsyl 3 18 4 1 0 0 26
Integrated Genetics/Laboratory Corporation of America 6 6 1 1 3 0 17
Mendelics 2 0 8 2 0 0 12
Illumina Clinical Services Laboratory,Illumina 1 0 8 3 0 0 12
ITMI 0 0 0 0 0 8 8
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 2 1 0 4 0 0 7
OMIM 6 0 0 0 0 0 6
Genetic Services Laboratory, University of Chicago 0 0 4 2 0 0 6
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 1 1 2 0 2 0 6
PreventionGenetics 0 0 0 3 2 0 5
Fulgent Genetics,Fulgent Genetics 2 0 2 0 0 0 4
GeneReviews 3 0 0 0 0 0 3
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 2 1 0 0 3
Division of Genomic Diagnostics,The Children's Hospital of Philadelphia 0 0 1 0 1 0 2
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 1 0 0 1
SNPedia 0 0 0 0 0 1 1
Genomic Research Center,Shahid Beheshti University of Medical Sciences 0 1 0 0 0 0 1
Division of Human Genetics,Children's Hospital of Philadelphia 0 1 0 0 0 0 1
Genetic Predisposition to Colorectal Cancer Group,Institut d’Investigacions Biomediques August Pi i Sunyer 0 1 0 0 0 0 1
Vantari Genetics 0 0 0 0 1 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Gharavi Laboratory,Columbia University 0 0 1 0 0 0 1

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