ClinVar Miner

Variants in gene FANCC

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
61 43 189 139 18 10 402

Condition and significance breakdown #

Total conditions: 10
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Fanconi anemia 45 7 107 59 7 0 225
Fanconi anemia, complementation group C 27 32 53 7 4 0 109
not provided 11 6 64 24 3 2 102
Hereditary cancer-predisposing syndrome 11 3 54 30 3 0 101
not specified 0 0 5 67 15 8 87
Malignant tumor of breast 3 0 6 6 3 0 18
Fanconi anemia, complementation group A 1 0 5 10 1 0 17
Hereditary breast and ovarian cancer syndrome 0 0 1 1 0 0 2
Carcinoma of colon 0 1 0 0 0 0 1
Familial ovarian cancer 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 34
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 45 7 107 67 7 0 233
GeneDx 9 6 49 70 14 0 148
Ambry Genetics 11 3 54 30 3 0 101
Leiden Open Variation Database 20 0 15 0 0 0 35
Natera, Inc. 1 0 25 4 1 0 31
Counsyl 1 21 4 1 0 0 27
Department of Pathology and Laboratory Medicine,Sinai Health System 4 0 10 7 3 0 24
Mendelics 2 0 10 10 1 0 23
Illumina Clinical Services Laboratory,Illumina 1 0 15 3 3 0 22
Baylor Genetics 13 3 5 0 0 0 21
Integrated Genetics/Laboratory Corporation of America 8 4 0 3 3 0 18
ITMI 0 0 0 0 0 8 8
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 2 1 0 4 0 0 7
Myriad Women's Health, Inc. 2 5 0 0 0 0 7
OMIM 6 0 0 0 0 0 6
Genetic Services Laboratory, University of Chicago 0 0 3 2 1 0 6
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics 1 1 2 0 2 0 6
PreventionGenetics, PreventionGenetics 0 0 0 3 2 0 5
CeGaT Praxis fuer Humangenetik Tuebingen 1 0 3 1 0 0 5
Fulgent Genetics,Fulgent Genetics 2 0 2 0 0 0 4
GeneReviews 3 0 0 0 0 0 3
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics,Children's Hospital of Philadelphia 0 0 1 0 1 0 2
Cancer Genomics Group,Japanese Foundation For Cancer Research 0 0 1 1 0 0 2
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 0 1 0 0 1
SNPedia 0 0 0 0 0 1 1
Genomic Research Center, Shahid Beheshti University of Medical Sciences 1 0 0 0 0 0 1
Division of Human Genetics,Children's Hospital of Philadelphia 0 1 0 0 0 0 1
Genetic Predisposition to Colorectal Cancer Group,Institut d’Investigacions Biomediques August Pi i Sunyer 0 1 0 0 0 0 1
Vantari Genetics 0 0 0 0 1 0 1
Institute of Human Genetics, University of Leipzig Medical Center 1 0 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Gharavi Laboratory,Columbia University 0 0 1 0 0 0 1
Reproductive Health Research and Development,BGI Genomics 1 0 0 0 0 0 1
Nilou-Genome Lab 0 0 0 0 1 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.