List of variants in gene FBXL4 reported as uncertain significance by Invitae

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 101

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_001278716.2(FBXL4):c.1388T>C (p.Met463Thr)	rs146638016	0.00047
NM_001278716.2(FBXL4):c.1594C>G (p.Leu532Val)	rs150523994	0.00019
NM_001278716.2(FBXL4):c.527G>C (p.Trp176Ser)	rs201858974	0.00016
NM_001278716.2(FBXL4):c.91A>G (p.Met31Val)	rs148934429	0.00013
NM_001278716.2(FBXL4):c.1126G>A (p.Glu376Lys)	rs745512025	0.00010
NM_001278716.2(FBXL4):c.1546C>T (p.Pro516Ser)	rs145806027	0.00009
NM_001278716.2(FBXL4):c.1400A>G (p.Tyr467Cys)	rs761551398	0.00006
NM_001278716.2(FBXL4):c.61C>T (p.Arg21Cys)	rs369518305	0.00006
NM_001278716.2(FBXL4):c.752A>G (p.Tyr251Cys)	rs758776562	0.00006
NM_001278716.2(FBXL4):c.1135C>T (p.Arg379Cys)	rs778692687	0.00005
NM_001278716.2(FBXL4):c.1214C>A (p.Ala405Asp)	rs140490040	0.00004
NM_001278716.2(FBXL4):c.1826G>A (p.Ser609Asn)	rs371875653	0.00004
NM_001278716.2(FBXL4):c.526T>C (p.Trp176Arg)	rs201149065	0.00004
NM_001278716.2(FBXL4):c.565C>T (p.Arg189Cys)	rs373308410	0.00004
NM_001278716.2(FBXL4):c.1156C>T (p.His386Tyr)	rs751643380	0.00003
NM_001278716.2(FBXL4):c.1172C>G (p.Thr391Ser)	rs750610341	0.00003
NM_001278716.2(FBXL4):c.1289G>A (p.Arg430Gln)	rs377537581	0.00003
NM_001278716.2(FBXL4):c.1713G>A (p.Met571Ile)	rs767419935	0.00003
NM_001278716.2(FBXL4):c.434C>G (p.Thr145Ser)	rs755971635	0.00003
NM_001278716.2(FBXL4):c.58C>T (p.Arg20Trp)	rs758088733	0.00003
NM_001278716.2(FBXL4):c.8C>T (p.Pro3Leu)	rs561491659	0.00003
NM_001278716.2(FBXL4):c.1037T>C (p.Leu346Pro)	rs186727069	0.00002
NM_001278716.2(FBXL4):c.1069A>G (p.Asn357Asp)	rs199540184	0.00002
NM_001278716.2(FBXL4):c.1244C>T (p.Pro415Leu)	rs770653005	0.00002
NM_001278716.2(FBXL4):c.1285A>G (p.Lys429Glu)	rs1554218803	0.00002
NM_001278716.2(FBXL4):c.1304G>A (p.Arg435Gln)	rs754142863	0.00002
NM_001278716.2(FBXL4):c.1483A>C (p.Asn495His)	rs568736395	0.00002
NM_001278716.2(FBXL4):c.529T>A (p.Ser177Thr)	rs753998502	0.00002
NM_001278716.2(FBXL4):c.988G>A (p.Ala330Thr)	rs759851318	0.00002
NM_001278716.2(FBXL4):c.991A>G (p.Lys331Glu)	rs749668327	0.00002
NM_001278716.2(FBXL4):c.1025C>G (p.Ser342Cys)	rs780707718	0.00001
NM_001278716.2(FBXL4):c.1136G>A (p.Arg379His)	rs756984960	0.00001
NM_001278716.2(FBXL4):c.1252G>A (p.Ala418Thr)	rs542852839	0.00001
NM_001278716.2(FBXL4):c.1294G>A (p.Val432Ile)	rs760332582	0.00001
NM_001278716.2(FBXL4):c.1297C>T (p.Leu433Phe)	rs1273843469	0.00001
NM_001278716.2(FBXL4):c.1346T>C (p.Phe449Ser)	rs1317325730	0.00001
NM_001278716.2(FBXL4):c.1379G>A (p.Ser460Asn)	rs762621252	0.00001
NM_001278716.2(FBXL4):c.1430A>C (p.Lys477Thr)	rs1003495628	0.00001
NM_001278716.2(FBXL4):c.1564A>G (p.Thr522Ala)	rs775291550	0.00001
NM_001278716.2(FBXL4):c.1787C>T (p.Ser596Leu)	rs542778224	0.00001
NM_001278716.2(FBXL4):c.371A>G (p.Gln124Arg)	rs370408625	0.00001
NM_001278716.2(FBXL4):c.433A>G (p.Thr145Ala)	rs1179798985	0.00001
NM_001278716.2(FBXL4):c.440A>G (p.His147Arg)	rs748016378	0.00001
NM_001278716.2(FBXL4):c.493A>C (p.Asn165His)	rs761003289	0.00001
NM_001278716.2(FBXL4):c.532G>A (p.Glu178Lys)	rs199923936	0.00001
NM_001278716.2(FBXL4):c.539C>T (p.Pro180Leu)	rs1015958378	0.00001
NM_001278716.2(FBXL4):c.736A>G (p.Ile246Val)	rs148621221	0.00001
NM_001278716.2(FBXL4):c.763G>C (p.Asp255His)	rs1772404815	0.00001
NM_001278716.2(FBXL4):c.776T>C (p.Met259Thr)	rs376909719	0.00001
NM_001278716.2(FBXL4):c.782G>A (p.Ser261Asn)	rs763612215	0.00001
NM_001278716.2(FBXL4):c.901T>C (p.Cys301Arg)	rs747126681	0.00001
NM_001278716.2(FBXL4):c.971A>G (p.Asn324Ser)	rs115763595	0.00001
NM_001278716.2(FBXL4):c.1007C>T (p.Ser336Phe)
NM_001278716.2(FBXL4):c.1056A>T (p.Leu352Phe)	rs779748858
NM_001278716.2(FBXL4):c.113T>C (p.Ile38Thr)
NM_001278716.2(FBXL4):c.115G>A (p.Glu39Lys)
NM_001278716.2(FBXL4):c.116A>G (p.Glu39Gly)
NM_001278716.2(FBXL4):c.1277G>A (p.Cys426Tyr)
NM_001278716.2(FBXL4):c.1285A>C (p.Lys429Gln)	rs1554218803
NM_001278716.2(FBXL4):c.1349G>C (p.Cys450Ser)
NM_001278716.2(FBXL4):c.1377C>T (p.Gly459=)
NM_001278716.2(FBXL4):c.1403A>G (p.Asp468Gly)
NM_001278716.2(FBXL4):c.1421T>C (p.Ile474Thr)
NM_001278716.2(FBXL4):c.1502C>A (p.Ala501Asp)
NM_001278716.2(FBXL4):c.1531G>T (p.Asp511Tyr)
NM_001278716.2(FBXL4):c.1615T>C (p.Phe539Leu)
NM_001278716.2(FBXL4):c.1628A>G (p.Asn543Ser)
NM_001278716.2(FBXL4):c.1655A>G (p.Asp552Gly)
NM_001278716.2(FBXL4):c.1673G>A (p.Cys558Tyr)	rs995995791
NM_001278716.2(FBXL4):c.16C>T (p.Pro6Ser)
NM_001278716.2(FBXL4):c.1721C>T (p.Pro574Leu)	rs779731686
NM_001278716.2(FBXL4):c.1757A>G (p.Asp586Gly)
NM_001278716.2(FBXL4):c.1763C>G (p.Ser588Cys)
NM_001278716.2(FBXL4):c.1784G>C (p.Cys595Ser)	rs2128374842
NM_001278716.2(FBXL4):c.1831C>G (p.Pro611Ala)	rs1770575412
NM_001278716.2(FBXL4):c.1846A>G (p.Lys616Glu)
NM_001278716.2(FBXL4):c.1852_1853del (p.Ser618fs)
NM_001278716.2(FBXL4):c.28G>C (p.Val10Leu)
NM_001278716.2(FBXL4):c.296C>A (p.Thr99Asn)
NM_001278716.2(FBXL4):c.355C>A (p.Pro119Thr)
NM_001278716.2(FBXL4):c.35C>G (p.Thr12Ser)
NM_001278716.2(FBXL4):c.379G>A (p.Val127Met)
NM_001278716.2(FBXL4):c.422A>G (p.His141Arg)
NM_001278716.2(FBXL4):c.436T>A (p.Tyr146Asn)
NM_001278716.2(FBXL4):c.443C>T (p.Pro148Leu)	rs755008031
NM_001278716.2(FBXL4):c.49A>T (p.Ile17Leu)	rs754509338
NM_001278716.2(FBXL4):c.50T>C (p.Ile17Thr)
NM_001278716.2(FBXL4):c.512+3A>G
NM_001278716.2(FBXL4):c.513-5G>A
NM_001278716.2(FBXL4):c.537A>T (p.Arg179Ser)
NM_001278716.2(FBXL4):c.601C>T (p.Pro201Ser)	rs746878388
NM_001278716.2(FBXL4):c.613A>G (p.Ile205Val)
NM_001278716.2(FBXL4):c.65G>C (p.Arg22Pro)	rs147696366
NM_001278716.2(FBXL4):c.72G>T (p.Arg24Ser)
NM_001278716.2(FBXL4):c.762G>T (p.Lys254Asn)
NM_001278716.2(FBXL4):c.780C>A (p.Asp260Glu)
NM_001278716.2(FBXL4):c.817G>C (p.Glu273Gln)
NM_001278716.2(FBXL4):c.929T>C (p.Leu310Pro)	rs2128393288
NM_001278716.2(FBXL4):c.961A>G (p.Ile321Val)	rs765148228
NM_001278716.2(FBXL4):c.989C>G (p.Ala330Gly)	rs368886622
NM_001278716.2(FBXL4):c.998A>G (p.Asp333Gly)

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.