ClinVar Miner

Variants in gene FOXP1

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If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign association total
50 22 112 79 27 1 273

Condition and significance breakdown #

Total conditions: 15
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Condition pathogenic likely pathogenic uncertain significance likely benign benign association total
Intellectual Disability with Language Impairment and Autistic Features 0 0 75 44 9 0 128
not provided 25 10 17 16 13 0 80
Mental retardation with language impairment and with or without autistic features 23 7 6 0 0 0 35
not specified 0 0 10 14 6 0 27
History of neurodevelopmental disorder 0 0 4 12 5 0 21
Inborn genetic diseases 3 1 2 0 0 0 6
Intellectual disability 0 1 0 3 0 0 4
Mental retardation with language impairment and with or without autistic features; Cerebellar vermis hypoplasia 1 1 0 0 0 0 2
See cases 1 1 0 0 0 0 2
Anterior creases of earlobe; Delayed speech and language development; Strabismus; Glabellar hemangioma; Intellectual disability 0 1 0 0 0 0 1
Atrioventricular septal defect; Pulmonary atresia with ventricular septal defect; Heterotaxia; Single Ventricle Defect 0 0 0 0 0 1 1
Autistic disorder of childhood onset 0 1 0 0 0 0 1
Autistic disorder of childhood onset; Intellectual disability 1 0 0 0 0 0 1
Hypoplastic left heart syndrome 1; Aortic valve atresia (disease); Mitral atresia disorder 0 0 0 0 0 1 1
Seizures; Intellectual disability 1 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 40
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign association total
Illumina Clinical Services Laboratory,Illumina 0 0 75 44 9 0 128
GeneDx 19 6 1 1 1 0 28
Ambry Genetics 3 1 6 12 5 0 27
Genetic Services Laboratory, University of Chicago 3 0 9 8 2 0 22
Invitae 0 1 0 11 10 0 22
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 6 1 5 5 4 0 21
CeGaT Praxis fuer Humangenetik Tuebingen 2 2 9 1 0 0 14
OMIM 6 0 0 0 0 0 6
Mendelics 2 2 2 0 0 0 6
Baylor Genetics 3 0 1 0 0 0 4
Language and Genetics Department,Max Planck Institute for Psycholinguistics 4 0 0 0 0 0 4
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 0 0 0 4 0 0 4
Department of Genetics, Rouen University Hospital, Normandy Center for Genomic and Personalized Medicine 3 1 0 0 0 0 4
Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics, Cincinnati Children's Hospital Medical Center 0 0 0 0 3 0 3
Centre de Biologie Pathologie Génétique, Centre Hospitalier Universitaire de Lille 0 0 0 3 0 0 3
Quest Diagnostics Nichols Institute San Juan Capistrano 1 0 1 0 0 0 2
Dobyns Lab,Seattle Children's Research Institute 1 1 0 0 0 0 2
Center for Human Genetics and Laboratory Diagnostics, Dr. Klein, Dr. Rost and Colleagues 0 0 2 0 0 0 2
Génétique des Maladies du Développement, Hospices Civils de Lyon 0 2 0 0 0 0 2
Division of Genomic Diagnostics,The Children's Hospital of Philadelphia 0 0 1 0 0 0 1
Molecular Genetics Laboratory,BC Children's and BC Women's Hospitals 1 0 0 0 0 0 1
ARUP Laboratories, Cytogenetics and Genomic Microarray,ARUP Laboratories 1 0 0 0 0 0 1
Integrated Genetics/Laboratory Corporation of America 0 1 0 0 0 0 1
Lineagen, Inc 0 0 1 0 0 0 1
Garg Lab, Nationwide Children's Hospital 0 0 0 0 0 1 1
Fulgent Genetics,Fulgent Genetics 0 1 0 0 0 0 1
Institute of Human Genetics,Klinikum rechts der Isar 1 0 0 0 0 0 1
Genomic Research Center, Shahid Beheshti University of Medical Sciences 0 0 1 0 0 0 1
UCLA Clinical Genomics Center, UCLA 0 1 0 0 0 0 1
Center of Genomic medicine, Geneva,University Hospital of Geneva 1 0 0 0 0 0 1
Genetic Diagnostic Laboratory,University of Szeged 1 0 0 0 0 0 1
Laboratory of Molecular Genetics,CHU RENNES 0 1 0 0 0 0 1
Clinical Cytogenomics Laboratory,Laboratory for Precision Diagnostics, University of Washington 0 1 0 0 0 0 1
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 1 0 0 0 0 1
Equipe Genetique des Anomalies du Developpement, Université de Bourgogne 1 0 0 0 0 0 1
Groupe Hospitalier Pitie Salpetriere, UF Genomique du Developpement,Assistance Publique Hopitaux de Paris 1 0 0 0 0 0 1
Human Genetics Institute Leipzig, Universitätsklinikum Leipzig 1 0 0 0 0 0 1
Laboratoire de Genetique Biologique, CHU de Poitiers 1 0 0 0 0 0 1
Institute for Genomic Medicine (IGM) Clinical Laboratory,Nationwide Children's Hospital 0 0 0 1 0 0 1
Biochemistry Laboratory of CDMU,Chengde Medical University 1 0 0 0 0 0 1

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