List of variants in gene GLDC reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 89

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_000170.3(GLDC):c.2863G>A (p.Val955Ile)	rs148540696	0.00078
NM_000170.3(GLDC):c.166C>T (p.Leu56Phe)	rs374342418	0.00044
NM_000170.3(GLDC):c.698T>C (p.Val233Ala)	rs140013612	0.00034
NM_000170.3(GLDC):c.1000T>C (p.Phe334Leu)	rs149133229	0.00031
NM_000170.3(GLDC):c.329C>A (p.Pro110His)	rs371491621	0.00029
NM_000170.3(GLDC):c.619C>G (p.Leu207Val)	rs142181803	0.00027
NM_000170.3(GLDC):c.2126A>G (p.Asn709Ser)	rs150943866	0.00026
NM_000170.3(GLDC):c.700C>G (p.Gln234Glu)	rs150698281	0.00016
NM_000170.3(GLDC):c.110G>A (p.Ser37Asn)	rs763471932	0.00014
NM_000170.3(GLDC):c.1851-9C>G	rs377751310	0.00013
NM_000170.3(GLDC):c.2212T>A (p.Cys738Ser)	rs375850752	0.00010
NM_000170.3(GLDC):c.2230G>A (p.Gly744Arg)	rs370061961	0.00010
NM_000170.3(GLDC):c.2378A>T (p.Asp793Val)	rs150833015	0.00009
NM_000170.3(GLDC):c.832G>A (p.Glu278Lys)	rs779837711	0.00008
NM_000170.3(GLDC):c.2446G>A (p.Ala816Thr)	rs775834004	0.00007
NM_000170.3(GLDC):c.578A>G (p.Asn193Ser)	rs555919940	0.00007
NM_000170.3(GLDC):c.661G>A (p.Val221Ile)	rs144043066	0.00007
NM_000170.3(GLDC):c.1121G>A (p.Arg374Lys)	rs141065026	0.00006
NM_000170.3(GLDC):c.1940C>T (p.Pro647Leu)	rs201135624	0.00006
NM_000170.3(GLDC):c.2810G>A (p.Arg937His)	rs151100082	0.00006
NM_000170.3(GLDC):c.632A>G (p.Tyr211Cys)	rs139931025	0.00006
NM_000170.3(GLDC):c.1791G>C (p.Glu597Asp)	rs141875337	0.00005
NM_000170.3(GLDC):c.270G>C (p.Leu90Phe)	rs747736821	0.00005
NM_000170.3(GLDC):c.886C>A (p.Leu296Ile)	rs200413149	0.00005
NM_000170.3(GLDC):c.1424C>T (p.Thr475Ile)	rs750883330	0.00004
NM_000170.3(GLDC):c.2035G>A (p.Val679Ile)	rs778376889	0.00004
NM_000170.3(GLDC):c.2545A>G (p.Arg849Gly)	rs778000679	0.00004
NM_000170.3(GLDC):c.292A>G (p.Asn98Asp)	rs750964572	0.00004
NM_000170.3(GLDC):c.183C>A (p.Asp61Glu)	rs375497905	0.00003
NM_000170.3(GLDC):c.262G>A (p.Asp88Asn)	rs770826242	0.00003
NM_000170.3(GLDC):c.1342G>C (p.Glu448Gln)	rs777365335	0.00002
NM_000170.3(GLDC):c.1580+5G>C	rs764790596	0.00002
NM_000170.3(GLDC):c.2809C>T (p.Arg937Cys)	rs766928717	0.00002
NM_000170.3(GLDC):c.549G>A (p.Val183=)	rs371771891	0.00002
NM_000170.3(GLDC):c.1182G>A (p.Met394Ile)	rs1249681861	0.00001
NM_000170.3(GLDC):c.1333T>C (p.Ser445Pro)	rs756770984	0.00001
NM_000170.3(GLDC):c.1366C>T (p.Arg456Trp)	rs773119895	0.00001
NM_000170.3(GLDC):c.1525C>G (p.Pro509Ala)	rs557412758	0.00001
NM_000170.3(GLDC):c.163C>G (p.Arg55Gly)	rs755680488	0.00001
NM_000170.3(GLDC):c.2053G>T (p.Val685Leu)	rs367988640	0.00001
NM_000170.3(GLDC):c.2831C>T (p.Pro944Leu)	rs374969047	0.00001
NM_000170.3(GLDC):c.328C>T (p.Pro110Ser)	rs866641732	0.00001
NM_000170.3(GLDC):c.437C>T (p.Thr146Met)	rs376578742	0.00001
NM_000170.3(GLDC):c.446G>A (p.Arg149Gln)	rs538431715	0.00001
NM_000170.3(GLDC):c.503T>C (p.Val168Ala)	rs1241332349	0.00001
NM_000170.3(GLDC):c.544A>G (p.Met182Val)	rs541691467	0.00001
NM_000170.3(GLDC):c.838G>A (p.Val280Met)	rs1258949524	0.00001
NM_000170.3(GLDC):c.862-12C>G	rs767628262	0.00001
NM_000170.3(GLDC):c.1202C>T (p.Ser401Phe)	rs1563852496
NM_000170.3(GLDC):c.1300T>C (p.Phe434Leu)
NM_000170.3(GLDC):c.1340A>T (p.Lys447Met)	rs1161073883
NM_000170.3(GLDC):c.1372A>T (p.Ile458Phe)
NM_000170.3(GLDC):c.1394A>G (p.Asp465Gly)	rs2129852952
NM_000170.3(GLDC):c.1484_1489del	rs778109389
NM_000170.3(GLDC):c.1553C>T (p.Pro518Leu)	rs761064507
NM_000170.3(GLDC):c.172C>T (p.Pro58Ser)	rs780963698
NM_000170.3(GLDC):c.1831G>C (p.Val611Leu)	rs1554646513
NM_000170.3(GLDC):c.1871C>G (p.Ala624Gly)	rs779980470
NM_000170.3(GLDC):c.190G>A (p.Ala64Thr)	rs141601131
NM_000170.3(GLDC):c.1914G>C (p.Glu638Asp)	rs1200000126
NM_000170.3(GLDC):c.2011G>C (p.Asp671His)	rs2129734998
NM_000170.3(GLDC):c.2169G>T (p.Gln723His)	rs2129725996
NM_000170.3(GLDC):c.2212T>G (p.Cys738Gly)	rs375850752
NM_000170.3(GLDC):c.2297G>A (p.Gly766Asp)
NM_000170.3(GLDC):c.2353G>A (p.Val785Ile)	rs372101832
NM_000170.3(GLDC):c.2462T>C (p.Met821Thr)
NM_000170.3(GLDC):c.247G>C (p.Gly83Arg)	rs946962875
NM_000170.3(GLDC):c.2510C>T (p.Ala837Val)	rs1157130507
NM_000170.3(GLDC):c.2519T>A (p.Met840Lys)	rs386833561
NM_000170.3(GLDC):c.2528G>A (p.Arg843Gln)	rs1422108790
NM_000170.3(GLDC):c.2593T>A (p.Leu865Met)	rs375375700
NM_000170.3(GLDC):c.2617T>A (p.Ser873Thr)
NM_000170.3(GLDC):c.2632G>A (p.Ala878Thr)	rs2129663107
NM_000170.3(GLDC):c.276G>C (p.Glu92Asp)	rs2130029415
NM_000170.3(GLDC):c.2894C>T (p.Ser965Phe)	rs1489390970
NM_000170.3(GLDC):c.294C>A (p.Asn98Lys)	rs1819702080
NM_000170.3(GLDC):c.2995G>A (p.Val999Ile)	rs2129641188
NM_000170.3(GLDC):c.3002C>T (p.Thr1001Ile)	rs555776146
NM_000170.3(GLDC):c.43G>A (p.Gly15Arg)
NM_000170.3(GLDC):c.488C>T (p.Pro163Leu)
NM_000170.3(GLDC):c.502G>A (p.Val168Met)	rs936791052
NM_000170.3(GLDC):c.580G>A (p.Ala194Thr)
NM_000170.3(GLDC):c.635G>A (p.Arg212Lys)	rs386833584
NM_000170.3(GLDC):c.635G>T (p.Arg212Ile)	rs386833584
NM_000170.3(GLDC):c.790T>C (p.Phe264Leu)	rs1038444873
NM_000170.3(GLDC):c.824A>T (p.Asp275Val)
NM_000170.3(GLDC):c.861+5G>C	rs192663616
NM_000170.3(GLDC):c.8C>A (p.Ser3Tyr)
NM_000170.3(GLDC):c.932A>G (p.Asp311Gly)	rs2129896343

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.