List of variants in gene LMNA reported as uncertain significance by Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 41

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HGVS	dbSNP	gnomAD frequency
NM_170707.4(LMNA):c.1634G>A (p.Arg545His)	rs142191737	0.00025
NM_170707.4(LMNA):c.895A>G (p.Ile299Val)	rs150924946	0.00016
NM_170707.4(LMNA):c.1201C>T (p.Arg401Cys)	rs61094188	0.00015
NM_170707.4(LMNA):c.1718C>T (p.Ser573Leu)	rs60890628	0.00011
NM_170707.4(LMNA):c.*6G>A	rs397517885	0.00010
NM_170707.4(LMNA):c.976T>A (p.Ser326Thr)	rs56851164	0.00009
NM_170707.4(LMNA):c.1567G>A (p.Gly523Arg)	rs201583907	0.00006
NM_170707.4(LMNA):c.350A>G (p.Lys117Arg)	rs397517901	0.00004
NM_170707.4(LMNA):c.986G>A (p.Arg329His)	rs397517913	0.00002
NM_170707.4(LMNA):c.1231G>T (p.Gly411Cys)	rs727504852	0.00001
NM_170707.4(LMNA):c.1303C>T (p.Arg435Cys)	rs150840924	0.00001
NM_170707.4(LMNA):c.1306A>G (p.Thr436Ala)	rs876657849	0.00001
NM_170707.4(LMNA):c.1363C>T (p.Arg455Cys)	rs397517892	0.00001
NM_170707.4(LMNA):c.1633C>T (p.Arg545Cys)	rs267607613	0.00001
NM_170707.4(LMNA):c.1699-8C>G	rs727503137	0.00001
NM_170707.4(LMNA):c.1751G>A (p.Arg584His)	rs56657623	0.00001
NM_170707.4(LMNA):c.1825G>A (p.Gly609Arg)	rs397517898	0.00001
NM_170707.4(LMNA):c.640-11A>C	rs727504932	0.00001
NM_170707.4(LMNA):c.749C>T (p.Ala250Val)	rs397517907	0.00001
NM_170707.4(LMNA):c.-12A>T	rs1553261811
NM_170707.4(LMNA):c.1130G>T (p.Arg377Leu)	rs61672878
NM_170707.4(LMNA):c.1158-3C>T	rs727503136
NM_170707.4(LMNA):c.1223A>C (p.Gln408Pro)	rs397517891
NM_170707.4(LMNA):c.1442A>G (p.Tyr481Cys)	rs397517893
NM_170707.4(LMNA):c.1748C>G (p.Ser583Trp)	rs59601651
NM_170707.4(LMNA):c.178C>T (p.Arg60Cys)	rs28928900
NM_170707.4(LMNA):c.1969-1G>T	rs1060499873
NM_170707.4(LMNA):c.215G>T (p.Arg72Leu)	rs727504340
NM_170707.4(LMNA):c.230T>C (p.Ile77Thr)	rs876657850
NM_170707.4(LMNA):c.232A>G (p.Lys78Glu)	rs876657851
NM_170707.4(LMNA):c.234G>C (p.Lys78Asn)	rs727505038
NM_170707.4(LMNA):c.266G>A (p.Arg89His)	rs59040894
NM_170707.4(LMNA):c.331G>C (p.Glu111Gln)	rs61726475
NM_170707.4(LMNA):c.343_344delinsTT (p.Glu115Leu)	rs727503134
NM_170707.4(LMNA):c.356G>C (p.Arg119Pro)	rs397517902
NM_170707.4(LMNA):c.629T>G (p.Ile210Ser)	rs267607572
NM_170707.4(LMNA):c.643C>G (p.Leu215Val)	rs397517905
NM_170707.4(LMNA):c.686T>C (p.Ile229Thr)	rs727505357
NM_170707.4(LMNA):c.739G>A (p.Glu247Lys)	rs727504373
NM_170707.4(LMNA):c.860C>T (p.Ala287Val)	rs397517910
NM_170707.4(LMNA):c.868G>A (p.Glu290Lys)	rs397517912

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