List of variants in gene MLH1 reported as uncertain significance by PreventionGenetics, part of Exact Sciences

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 37

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HGVS	dbSNP	gnomAD frequency
NM_000249.4(MLH1):c.626A>G (p.Asn209Ser)	rs150478207	0.00011
NM_000249.3(MLH1):c.-42C>T	rs41285097	0.00009
NM_000249.4(MLH1):c.242C>T (p.Thr81Ile)	rs63751069	0.00006
NM_000249.4(MLH1):c.955G>A (p.Glu319Lys)	rs63750796	0.00006
NM_000249.4(MLH1):c.1565G>A (p.Arg522Gln)	rs63751630	0.00004
NM_000249.4(MLH1):c.1633A>G (p.Thr545Ala)	rs267607840	0.00004
NM_000249.4(MLH1):c.52C>T (p.Arg18Cys)	rs367654552	0.00004
NM_000249.3(MLH1):c.-33T>G	rs201247839	0.00003
NM_000249.4(MLH1):c.991G>A (p.Glu331Lys)	rs550914672	0.00003
NM_000249.4(MLH1):c.1256T>C (p.Ile419Thr)	rs377484262	0.00002
NM_000249.4(MLH1):c.1564C>T (p.Arg522Trp)	rs63751703	0.00002
NM_000249.4(MLH1):c.776T>C (p.Leu259Ser)	rs56250509	0.00002
NM_000249.4(MLH1):c.1775G>C (p.Ser592Thr)	rs587782621	0.00001
NM_000249.4(MLH1):c.2162A>G (p.Tyr721Cys)	rs587778986	0.00001
NM_000249.4(MLH1):c.2167G>A (p.Ala723Thr)	rs1392532273	0.00001
NM_000249.4(MLH1):c.2228T>G (p.Leu743Arg)	rs864622258	0.00001
NM_000249.4(MLH1):c.452C>T (p.Thr151Met)	rs776969475	0.00001
NM_000249.4(MLH1):c.589-17T>A	rs754180618	0.00001
NM_000249.4(MLH1):c.976G>A (p.Val326Met)	rs730881739	0.00001
NM_000249.4(MLH1):c.1136A>G (p.Tyr379Cys)	rs143009528
NM_000249.4(MLH1):c.1136A>T (p.Tyr379Phe)	rs143009528
NM_000249.4(MLH1):c.125C>T (p.Ala42Val)	rs587778901
NM_000249.4(MLH1):c.1420C>T (p.Arg474Trp)	rs147939838
NM_000249.4(MLH1):c.1500_1502del (p.Ile501del)	rs587778920
NM_000249.4(MLH1):c.1559T>G (p.Val520Gly)	rs1200485334
NM_000249.4(MLH1):c.1925T>C (p.Leu642Pro)
NM_000249.4(MLH1):c.196A>G (p.Thr66Ala)	rs876660926
NM_000249.4(MLH1):c.2020G>A (p.Glu674Lys)	rs755577490
NM_000249.4(MLH1):c.2210A>T (p.Asp737Val)	rs267607885
NM_000249.4(MLH1):c.292G>C (p.Gly98Arg)	rs267607725
NM_000249.4(MLH1):c.31C>G (p.Leu11Val)	rs864622596
NM_000249.4(MLH1):c.454-3C>G	rs2082047640
NM_000249.4(MLH1):c.463C>T (p.Leu155Phe)	rs749370894
NM_000249.4(MLH1):c.706A>G (p.Lys236Glu)	rs1553645179
NM_000249.4(MLH1):c.748A>T (p.Asn250Tyr)	rs786203107
NM_000249.4(MLH1):c.74T>C (p.Ile25Thr)	rs63750514
NM_000249.4(MLH1):c.953A>G (p.His318Arg)	rs1559543995

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