List of variants in gene MPL reported by Natera, Inc.

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
		ClinVar version:

Total variants: 52

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HGVS	dbSNP	gnomAD frequency
NM_005373.3(MPL):c.690A>G (p.Glu230=)	rs16830693	0.05049
NM_005373.3(MPL):c.340G>A (p.Val114Met)	rs12731981	0.02191
NM_005373.3(MPL):c.117G>T (p.Lys39Asn)	rs17292650	0.01329
NM_005373.3(MPL):c.543T>C (p.Gly181=)	rs17572791	0.00819
NM_005373.3(MPL):c.1565+5C>T	rs41269541	0.00488
NM_005373.3(MPL):c.677C>A (p.Ser226Tyr)	rs141063159	0.00170
NM_005373.3(MPL):c.754T>C (p.Tyr252His)	rs141311765	0.00124
NM_005373.3(MPL):c.1488C>T (p.Thr496=)	rs140091584	0.00056
NM_005373.3(MPL):c.1570C>T (p.Leu524=)	rs146372205	0.00053
NM_005373.3(MPL):c.1336G>A (p.Gly446Arg)	rs561818288	0.00046
NM_005373.3(MPL):c.1102G>T (p.Val368Leu)	rs149810307	0.00039
NM_005373.3(MPL):c.1197G>A (p.Arg399=)	rs148945299	0.00039
NM_005373.3(MPL):c.305G>C (p.Arg102Pro)	rs28928907	0.00035
NM_005373.3(MPL):c.1536G>A (p.Leu512=)	rs137990502	0.00027
NM_005373.3(MPL):c.963G>T (p.Arg321=)	rs138636505	0.00024
NM_005373.3(MPL):c.549G>A (p.Thr183=)	rs147130173	0.00023
NM_005373.3(MPL):c.209C>T (p.Pro70Leu)	rs61754776	0.00021
NM_005373.3(MPL):c.1063A>G (p.Lys355Glu)	rs546510242	0.00017
NM_005373.3(MPL):c.655C>G (p.Gln219Glu)	rs142737453	0.00017
NM_005373.3(MPL):c.769C>T (p.Arg257Cys)	rs121913611	0.00011
NM_005373.3(MPL):c.1467C>T (p.Thr489=)	rs759161511	0.00009
NM_005373.3(MPL):c.1650C>T (p.Ser550=)	rs377715574	0.00007
NM_005373.3(MPL):c.318G>A (p.Pro106=)	rs370001905	0.00007
NM_005373.3(MPL):c.1446G>A (p.Arg482=)	rs1046680606	0.00006
NM_005373.3(MPL):c.304C>T (p.Arg102Cys)	rs763568293	0.00006
NM_005373.3(MPL):c.622C>A (p.Gln208Lys)	rs111460954	0.00006
NM_005373.3(MPL):c.1002C>T (p.Cys334=)	rs141526418	0.00005
NM_005373.3(MPL):c.1051C>T (p.Arg351Cys)	rs201998783	0.00005
NM_005373.3(MPL):c.173C>T (p.Ala58Val)	rs6087	0.00005
NM_005373.3(MPL):c.235_236del (p.Leu79fs)	rs587778514	0.00005
NM_005373.3(MPL):c.127C>T (p.Arg43Ter)	rs148434485	0.00004
NM_005373.3(MPL):c.1629T>C (p.Leu543=)	rs150816330	0.00004
NM_005373.3(MPL):c.212G>A (p.Arg71Gln)	rs368753117	0.00003
NM_005373.3(MPL):c.548C>T (p.Thr183Met)	rs137952228	0.00003
NM_005373.3(MPL):c.932C>T (p.Ser311Phe)	rs776753502	0.00003
NM_005373.3(MPL):c.1645C>G (p.Leu549Val)	rs746440317	0.00002
NM_005373.3(MPL):c.1119T>C (p.Gly373=)	rs748581599	0.00001
NM_005373.3(MPL):c.1134C>T (p.Tyr378=)	rs749571171	0.00001
NM_005373.3(MPL):c.1178C>T (p.Thr393Ile)	rs779132175	0.00001
NM_005373.3(MPL):c.1309-1G>T	rs1243113655	0.00001
NM_005373.3(MPL):c.1463A>G (p.Glu488Gly)	rs1328988667	0.00001
NM_005373.3(MPL):c.237G>C (p.Leu79=)	rs769101640	0.00001
NM_005373.3(MPL):c.273C>T (p.Tyr91=)	rs759361904	0.00001
NM_005373.3(MPL):c.464A>T (p.Glu155Val)	rs780341646	0.00001
NM_005373.3(MPL):c.981-1G>C	rs769297582	0.00001
NM_005373.3(MPL):c.1437C>T (p.Asp479=)	rs865799838
NM_005373.3(MPL):c.1904C>T (p.Pro635Leu)	rs121913612
NM_005373.3(MPL):c.268C>T (p.Arg90Ter)	rs763144679
NM_005373.3(MPL):c.378del (p.Phe126fs)	rs587778515
NM_005373.3(MPL):c.408C>G (p.Pro136=)	rs146579984
NM_005373.3(MPL):c.844G>A (p.Gly282Arg)	rs878854770
NM_005373.3(MPL):c.988A>T (p.Ile330Phe)	rs1647056598

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