ClinVar Miner

List of variants in gene MSH2 reported as uncertain significance for Lynch syndrome

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Total variants: 159
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HGVS dbSNP
NC_000002.11:g.(?_47698104)_(47710367_?)dup
NC_000002.12:g.(?_47482779)_(47482949_?)del
NM_000251.2(MSH2):c.-125_1076+?dup1201
NM_000251.2(MSH2):c.-12G>A rs1558450937
NM_000251.2(MSH2):c.-181G>A rs786201698
NM_000251.2(MSH2):c.1006C>A (p.Pro336Thr) rs63751062
NM_000251.2(MSH2):c.1012G>A (p.Gly338Arg) rs63751004
NM_000251.2(MSH2):c.1013G>C (p.Gly338Ala) rs587779065
NM_000251.2(MSH2):c.1029C>A (p.Asn343Lys) rs1060501995
NM_000251.2(MSH2):c.1033T>G (p.Trp345Gly) rs1558466616
NM_000251.2(MSH2):c.103C>T (p.Arg35Cys) rs1060502034
NM_000251.2(MSH2):c.104G>A (p.Arg35His) rs1060502012
NM_000251.2(MSH2):c.1071G>A (p.Glu357=) rs587781617
NM_000251.2(MSH2):c.1111G>C (p.Glu371Gln) rs1060501994
NM_000251.2(MSH2):c.1118G>A (p.Arg373Lys) rs864622254
NM_000251.2(MSH2):c.112G>T (p.Asp38Tyr) rs730881761
NM_000251.2(MSH2):c.115_123del (p.Arg39_Asp41del) rs863224831
NM_000251.2(MSH2):c.1172C>T (p.Ala391Val) rs864622674
NM_000251.2(MSH2):c.1191A>T (p.Gln397His) rs768694189
NM_000251.2(MSH2):c.1225C>G (p.Gln409Glu) rs151244108
NM_000251.2(MSH2):c.1264G>A (p.Glu422Lys) rs63751712
NM_000251.2(MSH2):c.1277-14C>G rs267607951
NM_000251.2(MSH2):c.1347G>C (p.Lys449Asn) rs587781331
NM_000251.2(MSH2):c.1357A>C (p.Met453Leu) rs1558493602
NM_000251.2(MSH2):c.1429A>C (p.Asn477His) rs587781346
NM_000251.2(MSH2):c.1461C>G (p.Asp487Glu) rs35107951
NM_000251.2(MSH2):c.1469A>G (p.Lys490Arg) rs1060502008
NM_000251.2(MSH2):c.14C>A (p.Pro5Gln) rs56170584
NM_000251.2(MSH2):c.1510+6_1510+7del rs1060502013
NM_000251.2(MSH2):c.1550C>T (p.Ala517Val) rs1060501997
NM_000251.2(MSH2):c.1600C>T (p.Arg534Cys) rs63750029
NM_000251.2(MSH2):c.1638G>C (p.Lys546Asn) rs372350768
NM_000251.2(MSH2):c.1659C>T (p.Asn553=) rs869312796
NM_000251.2(MSH2):c.1662-18T>C rs376235435
NM_000251.2(MSH2):c.167A>T (p.Glu56Val) rs587782004
NM_000251.2(MSH2):c.1699A>G (p.Lys567Glu) rs63751149
NM_000251.2(MSH2):c.1726G>C (p.Ala576Pro) rs587779107
NM_000251.2(MSH2):c.1748A>G (p.Asn583Ser) rs201118107
NM_000251.2(MSH2):c.1759+3A>T rs863224630
NM_000251.2(MSH2):c.1796T>C (p.Leu599Ser) rs747504492
NM_000251.2(MSH2):c.1803G>C (p.Gln601His) rs1553368556
NM_000251.2(MSH2):c.1805T>C (p.Leu602Pro) rs1553368561
NM_000251.2(MSH2):c.1807G>A (p.Asp603Asn) rs63750657
NM_000251.2(MSH2):c.1813G>C (p.Val605Leu) rs730881777
NM_000251.2(MSH2):c.1818_1877del (p.Ser607_Glu626del) rs1553368576
NM_000251.2(MSH2):c.181C>G (p.Gln61Glu) rs63750951
NM_000251.2(MSH2):c.1862G>A (p.Arg621Gln) rs759263820
NM_000251.2(MSH2):c.1937A>G (p.Asp646Gly) rs41295290
NM_000251.2(MSH2):c.1963G>A (p.Val655Ile) rs549467183
NM_000251.2(MSH2):c.1980T>A (p.Asp660Glu) rs1060501988
NM_000251.2(MSH2):c.1A>C (p.Met1Leu) rs267607911
NM_000251.2(MSH2):c.1A>T (p.Met1Leu) rs267607911
NM_000251.2(MSH2):c.2005+6A>C rs1060502018
NM_000251.2(MSH2):c.2006-1G>T rs267607988
NM_000251.2(MSH2):c.2006G>A (p.Gly669Asp) rs63751640
NM_000251.2(MSH2):c.2017G>A (p.Gly673Arg) rs1558519543
NM_000251.2(MSH2):c.2032T>C (p.Tyr678His) rs876659093
NM_000251.2(MSH2):c.2073T>G (p.Ile691Met) rs779101144
NM_000251.2(MSH2):c.2075G>A (p.Gly692Glu) rs63751432
NM_000251.2(MSH2):c.2077T>C (p.Cys693Arg) rs1558519728
NM_000251.2(MSH2):c.2086C>G (p.Pro696Ala) rs546201898
NM_000251.2(MSH2):c.209C>A (p.Ala70Glu) rs587782481
NM_000251.2(MSH2):c.212-3A>T rs879255341
NM_000251.2(MSH2):c.2125T>G (p.Leu709Val) rs1060502030
NM_000251.2(MSH2):c.2132G>A (p.Arg711Gln) rs138465383
NM_000251.2(MSH2):c.2178G>A (p.Met726Ile) rs587782396
NM_000251.2(MSH2):c.2178G>C (p.Met726Ile) rs587782396
NM_000251.2(MSH2):c.2205C>T (p.Ile735=) rs533553381
NM_000251.2(MSH2):c.2242G>C (p.Asp748His) rs267608007
NM_000251.2(MSH2):c.2282G>C (p.Gly761Ala) rs876659937
NM_000251.2(MSH2):c.2285T>C (p.Leu762Ser) rs1558521698
NM_000251.2(MSH2):c.228G>T (p.Gln76His) rs587782857
NM_000251.2(MSH2):c.2294C>T (p.Ala765Val) rs1261458082
NM_000251.2(MSH2):c.2308A>G (p.Ile770Val) rs63750684
NM_000251.2(MSH2):c.2321T>G (p.Ile774Ser) rs878853811
NM_000251.2(MSH2):c.2360T>G (p.Leu787Arg) rs1558521929
NM_000251.2(MSH2):c.2366C>T (p.Ala789Val) rs876660292
NM_000251.2(MSH2):c.2410G>A (p.Ala804Thr) rs1060502005
NM_000251.2(MSH2):c.2458+3A>C rs761709497
NM_000251.2(MSH2):c.2479G>C (p.Gly827Arg) rs63750478
NM_000251.2(MSH2):c.2516A>G (p.His839Arg) rs63750027
NM_000251.2(MSH2):c.2591A>C (p.Asp864Ala) rs863224642
NM_000251.2(MSH2):c.2620T>G (p.Tyr874Asp) rs879254152
NM_000251.2(MSH2):c.2634G>C (p.Glu878Asp) rs63751624
NM_000251.2(MSH2):c.2699C>G (p.Ser900Ter) rs878853814
NM_000251.2(MSH2):c.2718A>G (p.Ile906Met) rs876659835
NM_000251.2(MSH2):c.2734A>C (p.Lys912Gln) rs1060501998
NM_000251.2(MSH2):c.2740G>T (p.Glu914Ter) rs267608024
NM_000251.2(MSH2):c.2754G>T (p.Lys918Asn) rs1553370893
NM_000251.2(MSH2):c.2782T>C (p.Ser928Pro) rs587781852
NM_000251.2(MSH2):c.2797dup (p.Thr933fs) rs587779156
NM_000251.2(MSH2):c.361T>A (p.Tyr121Asn) rs878853816
NM_000251.2(MSH2):c.365A>T (p.Lys122Met) rs863224643
NM_000251.2(MSH2):c.421A>G (p.Met141Val) rs193922374
NM_000251.2(MSH2):c.427G>A (p.Ala143Thr) rs878853817
NM_000251.2(MSH2):c.431C>G (p.Ser144Cys) rs878853818
NM_000251.2(MSH2):c.432C>T (p.Ser144=) rs1558459072
NM_000251.2(MSH2):c.480G>T (p.Gln160His) rs1558459273
NM_000251.2(MSH2):c.518T>C (p.Leu173Pro) rs63750070
NM_000251.2(MSH2):c.53G>A (p.Gly18Asp) rs1200418561
NM_000251.2(MSH2):c.587C>A (p.Pro196Gln) rs754478179
NM_000251.2(MSH2):c.605C>G (p.Pro202Arg) rs1060502002
NM_000251.2(MSH2):c.712T>G (p.Tyr238Asp) rs1060501987
NM_000251.2(MSH2):c.735G>C (p.Leu245Phe) rs864622271
NM_000251.2(MSH2):c.744A>C (p.Lys248Asn) rs1060502022
NM_000251.2(MSH2):c.781A>G (p.Met261Val) rs786201941
NM_000251.2(MSH2):c.792+6T>A rs553480072
NM_000251.2(MSH2):c.803C>T (p.Ser268Leu) rs563410947
NM_000251.2(MSH2):c.925G>C (p.Ala309Pro) rs781257094
NM_000251.2(MSH2):c.92C>G (p.Thr31Ser) rs746635262
NM_000251.2(MSH2):c.942+28_942+29del rs11309117
NM_000251.2(MSH2):c.94A>C (p.Thr32Pro) rs1060502033
NM_000251.2(MSH2):c.955G>T (p.Asp319Tyr) rs876660605
NM_000251.2(MSH2):c.95C>A (p.Thr32Asn) rs552361923
NM_000251.2(MSH2):c.982G>A (p.Ala328Thr) rs753237286
NM_000251.3(MSH2):c.1045C>G (p.Pro349Ala) rs267607939
NM_000251.3(MSH2):c.1130A>G (p.Gln377Arg) rs776174711
NM_000251.3(MSH2):c.1286A>C (p.Gln429Pro) rs1558493372
NM_000251.3(MSH2):c.128A>G (p.Tyr43Cys) rs17217723
NM_000251.3(MSH2):c.138C>G (p.His46Gln) rs33946261
NM_000251.3(MSH2):c.1547G>A (p.Ser516Asn) rs373564353
NM_000251.3(MSH2):c.1563T>C (p.Tyr521=) rs63750330
NM_000251.3(MSH2):c.1571G>A (p.Arg524His) rs63751207
NM_000251.3(MSH2):c.157G>T (p.Ala53Ser) rs755931648
NM_000251.3(MSH2):c.1595T>C (p.Val532Ala) rs754778750
NM_000251.3(MSH2):c.1724A>G (p.Asp575Gly) rs370330868
NM_000251.3(MSH2):c.1730T>C (p.Ile577Thr) rs63749910
NM_000251.3(MSH2):c.1787A>G (p.Asn596Ser) rs41295288
NM_000251.3(MSH2):c.1790A>C (p.Asp597Ala) rs548407418
NM_000251.3(MSH2):c.1813G>A (p.Val605Ile) rs730881777
NM_000251.3(MSH2):c.1847C>G (p.Pro616Arg) rs587779965
NM_000251.3(MSH2):c.1967A>G (p.Tyr656Cys) rs185356145
NM_000251.3(MSH2):c.1A>G (p.Met1Val) rs267607911
NM_000251.3(MSH2):c.2008C>T (p.Pro670Ser) rs1558519495
NM_000251.3(MSH2):c.2009C>A (p.Pro670His) rs41294982
NM_000251.3(MSH2):c.2012A>G (p.Asn671Ser) rs1558519505
NM_000251.3(MSH2):c.2039G>A (p.Arg680Gln) rs1203462814
NM_000251.3(MSH2):c.2111T>C (p.Ile704Thr) rs564657106
NM_000251.3(MSH2):c.212-2del rs1060502007
NM_000251.3(MSH2):c.2243A>T (p.Asp748Val) rs1558521518
NM_000251.3(MSH2):c.2417C>T (p.Thr806Ile) rs758889557
NM_000251.3(MSH2):c.2459-12A>G rs267608012
NM_000251.3(MSH2):c.2459G>A (p.Gly820Asp) rs794729229
NM_000251.3(MSH2):c.2533A>G (p.Lys845Glu) rs63750571
NM_000251.3(MSH2):c.2606C>A (p.Ala869Glu) rs730881772
NM_000251.3(MSH2):c.2766T>G (p.Phe922Leu) rs55859129
NM_000251.3(MSH2):c.2785C>T (p.Arg929Ter) rs551060742
NM_000251.3(MSH2):c.382C>G (p.Leu128Val) rs145649774
NM_000251.3(MSH2):c.435T>G (p.Ile145Met) rs63750124
NM_000251.3(MSH2):c.55T>C (p.Phe19Leu) rs141711342
NM_000251.3(MSH2):c.64T>A (p.Phe22Ile) rs1189127007
NM_000251.3(MSH2):c.716A>G (p.Gln239Arg) rs199676483
NM_000251.3(MSH2):c.80C>T (p.Pro27Leu) rs750746034
NM_000251.3(MSH2):c.815C>T (p.Ala272Val) rs34136999
NM_000251.3(MSH2):c.913G>A (p.Ala305Thr) rs63751454
NM_000251.3(MSH2):c.942+26_942+29del rs11309117
NM_000251.3(MSH2):c.97A>G (p.Thr33Ala) rs63751107
NM_000251.3(MSH2):c.992A>G (p.Asn331Ser) rs779673318
NM_001258281.1(MSH2):c.2356_2358GAG[1] (p.Glu787del) rs766906365

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